Day 1 Flashcards
(5 cards)
How do we use evidence based evidence to recommend therapies for a patient?
What is the PICO method?
How are clinical guidelines created?
1.convert the information needed into a clearly defined,answerable clinical question. 2. conduct a search of the best available evidence. 3: critically evaluating the validity,impact, and applicability of the evidence. 4: incorporating the evaluation with clinical expertise and patient individual factors.
Patient/problem, Intervention evaluated, Comparison intervention evaluated, outcome considered.
Select a topic of interest–> form a panel of experts–>define clinical evidence—> search evidence–> draft guideline–> conduct peer review–> implement guidelines–> plan follow up and updating of guidelines.
How do you evaluate primary literature?
What are the boolean operators?
What is the preferred form of technical writing?
consider impact of the journal, study designs, outcome/assessments, analysis, interpretation, extrapolation, references, drug company influence, peer review.
AND, OR, NOT
3rd person.
Who is the audience with pure technical style? Middle technical style? popular technical style?
What are MeSH terms?
Advantages of meta analysis?
professionals in the same field, professionals in other fields, lay person.
Medical subject headings.
increases sample size, decrease chance 2 error, statistically analyzes pool results
What are the major sections of summarizing a study?
Internal vs External validity?
What is selection bias? Observation bias?
Introduction, Methods, Results, Discussion
Internal is quality of the study, External is ability to apply the results to the population.
inclusion/exclusion criteria that limit generalizability. Subjects observed by different investigators.
Interviewer bias? What are the other bias?
Intention to treat?
patient interviews not conducted uniformly. Lost to follow, recall, publication, adherence, response.
Most closely resembles real world,
