DDS LAB_ QUIZ 1 Flashcards

(78 cards)

1
Q

LIQUID DOSAGE FORMS

A
  1. STERILE SOLUTIONS
  2. NON-STERILE SOLUTIONS
  3. SOLUTIONS
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2
Q

inserted directly to the body

A

STERILE SOLUTIONS

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3
Q

Example of Sterile Solutions

A

irrigation, nasal, optic, parenteral, ophthalmic

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4
Q

Example of non-sterile solutions

A

Mouthwash, Elixirs, Tinctures, Fluid extracts

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5
Q

Usually dissolved in water

A

Solutions

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6
Q

homogeneous solution

A

Solutions

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7
Q

Uniformity of doses

A

Solutions

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8
Q

Advantages of solutions:

A
  • Easier to swallow (children, geriatrics, & unconscious)
  • More quickly effective
  • homogeneous
  • dilute irritant actions
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9
Q

Disadvantages of solutions:

A
  • Bulky for transport
  • difficult to mask taste & odor
  • needs an accurate spoon to administer drug
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10
Q

indicates the maximum concentration to which a solution may be prepared with that solvent

A

SOLVENT

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11
Q

concentrated solution

A

Saturated solution

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12
Q

No more solute can be dissolved

A

Saturated solution

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13
Q

Diluted solution

A

Unsaturated solution

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14
Q

More solute that can be dissolve

A

Unsaturated/Diluted solution

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15
Q

dissolving the solute

A

simple solution

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16
Q

reacting 2 or more solutes

A

solution by chemical reaction

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17
Q

like dissolves like

A

solution by extraction

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18
Q

a number of medicinal agents and provided in a dry powder or granule form

A

dry mixture

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19
Q

for reconstitution with a prescribe amount of water

A

dry mixture

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20
Q

mostly antimicrobials

A

reconstitution

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21
Q

solute is surrounded by solvent particles

A

solvation

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22
Q

very soluble

A

<1

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23
Q

freely soluble

A

1-10

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24
Q

soluble

A

10-30

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25
sparingly soluble
30-100
26
slightly soluble
100-1000
27
very slightly soluble
1000-10000
28
practically insoluble
>10000
29
Normal saline solution
0.9% or 0.9g NaCl in 100ml of water
30
important factor in determining the solubility of a drug and in preparing its solution
temperature
31
heating can facilitate solubility
Temperature
32
weak acids or weak bases
pH of the solvent
33
ex: alkaloids
weak bases
34
ex: barbiturate drugs
weak acids
35
weak base + strong acid
salt (soluble)
36
weak acids + strong base
soluble salts
37
4th major factors affecting solubility
various chemicals and other properties of both solute and solvent
38
5th major factor affecting solubility
pressure
39
6th major factors affecting solubility
particle size
40
7th major factor affecting solubility
physical agitation
41
2nd major factor affecting solubility
temperature
42
1st major factor affecting solubility
solvent
43
3rd major factor affecting solubility
pH of the solvent
44
factors to consider in making solutions
- solution pH - buffers - isotonicity - viscosity - preservatives
45
Preservatives
1. Effective against a spectrum of wide organisms. 2. Stable 3. Non-toxic; non-sensitizing 4. Compatible w/ other ingredients 5. Free of taste and odor
46
Types of preservatives
1. Acidic 2. Neutral 3. Mercurials 4. Quarternary Ammonium Compounds
47
Benzoic acid What type of preservative?
Acidic
48
used to inhibit oxidation
Antioxidants
49
EDTA
ethylenediamine tetraacetic acid
50
1. sucrose 2. polyhydric alcohols
Sweetening agents
51
natural and parenteral resources
flavors & perfumes
52
Oral solutions
Internal Solutions
53
Parenteral Solutions
Internal Solutions
54
Vaginal, Rectal, Oral, Nasal, Topical
External Solutions
55
Solutions by simple solution
1. Calcium Hydroxide Solution USP
56
Calcium Hydroxide Solution USP
Lime hydrate/ caustic lime/ limewater
57
protects against extraneous solids
Well-closed container
58
protects from extraneous solids, liquids, or vapors
Tight container
59
impervious to air or any gases
Hermetic container
60
protects the contents from photochemical deterioration
Light resistant containers
61
Astringent
Toner
62
External
- Astringent - Topical Protective
63
Internal
- Antacid - Calcium Supplement
64
Strong Iodine Solution
Lungol's Solution
65
Thyroid crisis (storm)
Thyrotoxis
66
a condition in which thyroid gland makes too much thyroid hormone
Hyperthyroidism
67
Freezer
not exceeding 8 *c
68
refrigerator
not exceeding 8*c
69
cool
8*c - 15*c
70
room temperature
20*c - 25*c
71
controlled room temperature
0*c - 15*c
72
warm
30*c - 40*c
73
excessive heat
40*c and above
74
Mild ticture/ weal solution of iodine
Iodine Tincture
75
alcoholic or hydroalcoholic solution
Iodine tincture
76
contains active principles of crude drugs
iodine tincture
77
Betadine
Povidone Iodine Solution
78
Anticoagulant Sodium Citrate Solution USP
parental products