Deficiency of pituitary hormones Flashcards
(12 cards)
Hypogonadotropic hypogonadism presents with decreased :
Testosterone/estrogen and decreased LH & FSH
What is the likely diagnosis in a postpartum woman that presents with lactation failure, amenorrhea, fatigue, and hypotension for months after a spontaneous vaginal delivery complicated by severe postpartum hemorrhage?
Sheehan syndrome: hypopituitarism caused by ischemia and necrosis of the pituitary gland.
How can hypothyroidism lead to hyperprolactinemia?
Elevated TRH stimulates prolactin secretion from anterior pituitary
Nephrogenic diabetes insipidus may be caused by ____calcemia or____kalemia
hyper
hypo
What is the likely diagnosis in a patient with polyuria / polydipsia with hypernatremia, high serum osmolality, and low urine osmolality?
Diabetes insipidus
Which type of diabetes insipidus is characterized by a lack of response to the ADH secreted by the posterior pituitary?
Nephrogenic diabetes insipidus
What is the next step in management for an adolescent girl that presents with primary amenorrhea and absent breast development with a uterus present on ultrasound?
Measure serum FSH level
What is the next step in management for an adolescent girl with primary amenorrhea with a uterus present on ultrasound and low FSH levels?
Measure TSH/prolactin
What psychiatric medication is a common cause of drug-induced nephrogenic diabetes insipidus?
Lithium
Etiologies of central diabetes insipidus include:
Pituitary tumor, autoimmune, trauma, surgery, and ischemic encephalopathy
How does secretion of the following hormones change in secondary adrenal insufficiency?
Glucocorticoids:
- Androgens:
- Mineralocorticoids:
- decreased
- decreased
- normal (no change)
Frequent headaches, amenorrhea, and bitemporal hemianopia:
Pituitary apoplexy
