Osteoporosis/Paget's Disease/Rickets

Question 1

What osteoporosis drug has side effects that include acid reflux, esophagitis, and esophageal ulcers?

Answer 1

Bisphosphonates (oral)

Question 2

What is the preferred treatment for symptomatic patients with Paget disease of bone (Osteitis deformans)?

Answer 2

Bisphosphonates

Question 3

How do the serum levels of the following change with vitamin D deficiency?
- Ca2+:
- Phosphate:
- PTH:
- Alkaline phosphatase:

Answer 3

• Decrease
• Decrease
• Increase
• Increase

Question 4

How do the following laboratory values change in patients with Paget disease of bone?
- Serum calcium:
- Serum phosphorus:
- Alkaline phosphatase:
- PTH:

Answer 4

• No change
• No change
• Increase
• No change

Question 5

What is the likely diagnosis in an older patient with headache, bone pain, and hearing loss?

Answer 5

Paget disease of bone (osteitis deformans)

Question 6

How do the following laboratory values change in patients with osteoporosis?
- Serum calcium:
- Serum phosphorus:
- Alkaline phosphatase:
- PTH:

Answer 6

• No change
• No change
• No change
• No change

Question 7

Osteoporosis in a person who has celiac disease is due to malabsorption of :

Answer 7

vitamin D