DEFINITIONS

Question 1

ACETULCHOLINE (Ach)

Answer 1

A CHEMICAL PRODUCED BY THE BODY THAT IS USED IN THE TRANSMISSION OF THE NERVE IMPULSES. IT DESTROYED BY THE ENZYME CHOLINESTERASE

Question 2

ADRENERGIC (ADRENOMIMETIC)

Answer 2

REFERS TO A DRUG STIMULATING A RECEPTOR FOR NOREEPINEPHRINE OR EPINEPHRINE

Question 3

AFFERENT

Answer 3

SIGNALS THAT ARE TRANSMITTED TO THE BRAIN AND SPINAL CORD

Question 4

AGONIST

Answer 4

A CHEMICAL OR DRUG THAT BINDS TO A RECEPTOR AND CREATES AN EFFECT ON THE BODY

Question 5

ANTAGONIST

Answer 5

ACHEMICAL OR A DRUG THAT BINDS TO A RECEPTOR BUT DOES NOT CREATE AN EFFECT ON THE BODY IT ACTUALLY BLOCKS THE RECEPTOR SITE FROM ACEPTNG AN AGONIST.

Question 6

ANTICHOLINERGIC

Answer 6

REFERS TO A DRUG BLOCKING A RECEPTOR FOR ACETYLCHOLINE

Question 7

ANTIADRENERGIC

Answer 7

REFERS TO A DRUG BLOCKING A RECEPTOR FOR EPINEPRHINE OR NOREEPINEPHRINE

Question 8

BIOAVAILABILITY

Answer 8

AMOUNT OF DRUG THAT REACHES THE SYSTEMIC CIRCULATION

Question 9

CNS

Answer 9

A system that includes the brain and spinal cord, controlling voluntary and involuntary acts

Question 10

CHOLINERGIC (CHOLINOMIMETIC)

Answer 10

REFERS TO A DRUG CAUSING STIMULATION OF A RECEPTOR FOR ACETLYCHOLINE

Question 11

DRUG ADMINISRATION

Answer 11

METHOD BY WHICH THE DRUG IS MADE AVAILABLE TO THE BODY

Question 12

ED50

Answer 12

DOSE AT WHICH A DRUG PRODUCES 50% OF MAXIMAL EFFECT

Question 13

EFFERENT

Answer 13

SIGNALS THAT ARE TRANSMITTED FROM THE BRAIN AND SPINAL CORD

Question 14

ENTERAL

Answer 14

USE OF THE INTESTINE

Question 15

FIRST PASS EFFECT

Answer 15

INITIAL METABOLISM IN THE LIVER OF A DRUG TAKEN ORALLY BEFORE THE DRUG REACHES THE SYSTEMIC CIRCULATION

Question 16

GENERIC NAME

Answer 16

The name assigned to a chemical by the United States Adopted Name (USAN) Council when the chemical appears to have therapeutic use and the manufacturer wishes to market the drug

Question 17

HYPERSENSITIVITY

Answer 17

AN ALLERGIC OR IMMUNE MEDIATED REACTION TO A DRUG, WHICH CAN BE SERIOUS, REQUIRING AIRWAY MAMINTANANCE OR VENTILATOR ASSISTANCE

Question 18

IDIOSYNCRATIC EFFECT

Answer 18

AN ABNORMAL OR UNEXPECTED REACTION TO A DRUG OTHER THAN AN ALLERGIC REACTION AS COMPARED WITH THE PREDICTED EFFECT

Question 19

INHALATION

Answer 19

TAKING A SUBSTANCE, TYPICALLY IN THE FORM OF GASES, FUMES, VAPORS, MISTS,AEROSOLS, OR DUSTS, INTO THE BODY BY BREATHING

Question 20

LD50

Answer 20

LETHAL DOSE FOR 50% OF THE POPULATION

Question 21

LOCAL EFFECT

Answer 21

LIMITED TO THE AREA OF TREATMENT

Question 22

LUNG AVAILABILITY/ SYSTEMIC AVAILABILITY

Answer 22

(L/T RATIO )

AMOUNT OF DRUG THAT IS MADE AVAILABLE TO THE LUNG OUT OF THE TOTAL AVAILABLE TO THE BODY

Question 23

MEDICATION RECONSILIATION

Answer 23

The formal process in which healthcare providers work together with patients, families and care providers to ensure accurate and comprehensive medication information is communicated consistently across transitions of care

Question 24

NONPROPRIETARY NAME

Answer 24

THE NAME OF A DRUG OTHER THAN ITS TRADEMARKED NAME

Question 25

NOREPINEPHRINE

Answer 25

A NATURALLY OCCURING CATECHOLAMINE, PRODUCED BY THE ADRENAL GLAND MEDULLA, THAT HAS PROPERTIES SIMILAR TO THOSE OF EPINEPHRINE.

Question 26

PLACEBO

Answer 26

AN INERT SUBSTITUTE, CAUSING NO EFFECT

Question 27

RECEPTOR

Answer 27

A CELL COMPONENT THAT COMBINES WITH A DRUG TO A CHANGE OR ENCHANCE THE FUNCTION OF THE CELL

Question 28

STRUCTURE (SAR)

Answer 28

SAR- STRUCTURE ACTIVITY RELATION | IS THE RELATIONSHIP BRW A DRUG 'S CHEMICAL STRUCTURE AND THE OUTCOME IT HAS ON THE BODY

Question 29

SYMPATHOLYTIC

Answer 29

AN AGENT BLOCKING OR INHIBITING THE EFECT OF THE SYMPATHETIC NERVOUS SYSTEM

Question 30

SYMPATHOMIMETIC

Answer 30

AN AGENT CAUSING STIMULATION OF THE SNS

Question 31

SYNERGISM EFFECT

Answer 31

COMINED DRUGS EFFECTS THAT ARE ARE GREATER THATN IF THE DRUGS WERE GIVEN ALONE

Question 32

SYSTEMIC EFFECT

Answer 32

PERTAINS TO THE WHOLE BODY, DRUG IS NOT LIMITED TO LOCAL SITE, POSSIBLY CAUSING SIDE EFFECTS

Question 33

TACHYPHYLAXIS

Answer 33

A RAPID DECREASE IN RESPONSE TO A DRUG

Question 34

THERAPEUTIC INDEX

Answer 34

Difference between the minimal therapeutic and toxic concentrations of a drug; the smaller the difference the greater chance the drug will be toxic (THE GREATER THE NUMBER THE SAFER THE DRUG)

Question 35

TOLERANCE

Answer 35

DESCRIBES A DRECREASING INTENSITY OF RESPONSE TO A DRUG OVER TIME

Question 36

TOPICAL

Answer 36

USE OF THE SKIN OR MUCUS MEMBRANE (E.G LOTION )

Question 37

TOXICOLOGY

Answer 37

THE STUDY OF TOXIC SUSBTANCES AND THEU PAHRMACOLOGICAL ACTIONS, INCLUDING ANTIDOTES AND POISON CONTROL

Question 38

TRANSDERMAL

Answer 38

USE OF THE SKIN (EG PATCH)

Question 39

alpha 1

Answer 39

alpha1 receptors vasoconstrict located in vasculature peripheries, kidneys, GI tract

Question 40

alpha 2 receptors

Answer 40

causes vasodilation also found in CNS

Question 41

Beta 1

Answer 41

excitatory | locates in the heart muscle

Question 42

beta

Answer 42

exhibitory (relaxation) | bronchodilator