Dementia Flashcards

Define dementia. • Identify common types of dementia and their differential features. • Identify other clinical conditions on the differential diagnosis of dementia. • Identify helpful treatment interventions in dementia.

1
Q

dx of dementia

A

memory impairment + one of the following:

aphasia, apraxia, agnosia, disturbance in executive function

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2
Q

non diagnostic, but common dementia sx

A

visual/spatial deficits, gradual onset and progressive decline, psychosis

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3
Q

cortica; dementias (2)

A

alzheimer’s, frontotemporal

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4
Q

lobes affected by alzheimer’s

A

temporal and parietal

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5
Q

definitive dx of alzheimer’s

A

neurofibrillary plaques and tangles

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6
Q

allele linked to alzheimer’s

A

APOE4

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7
Q

sx of frontotemporal dementia

A

initial presentation of personality changes and disinhibition

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8
Q

dementia with tau inclusions

A

frontotemporal

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9
Q

subcortical dementia types (4)

A

huntington’s, wilson’s progressive supranuclear, limbic encephalopathy

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10
Q

paraneoplastic dementia

A

limbic encephalopathy

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11
Q

dementia sensitive to extrapyramidal sx from antipsychotics

A

lewy body dementia

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12
Q

dementia with parkinsonism and visual hallucinations (particularly little people)

A

lewy body

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13
Q

rapid, stepwise dementia caused by

A

vasculat dementia

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14
Q

imaging findings in vascular dementia

A

old infartcs, lacunae, diffuse white matter changes, subdural hematomas

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15
Q

treatable dementia presenting with gait apraxia and incontinence

A

normal pressure hydrocephalus

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16
Q

reversable ddx of dementia

A

obstructive sleep dementia, depression, malnutrition, toxic/metabolic issues

17
Q

predisposng illness to normal pressure hydrocephalus

A

sudural hematoma, meningitis, tertiary syphilis, collagen vascular dx

18
Q

treatment for normal pressure hydrocephalus

A

shunting

19
Q

sx of b12 deficiency

A

macrocytic anemia, glive stocking sensory loss, dementia

20
Q

acetylcholinesterase inhibitors for dementia

A

donepezil, rivastigmine, galantamine

21
Q

MOA of memantine

A

glutamate blockade, preventing excitotxicity

22
Q

risk in treating elderly with new generation antipsychotics

A

CVA

23
Q

sleep aid for dementia

A

trazadone

24
Q

treatment for agitation in dementia

A

mood stabilizer