Dementia Flashcards
Define dementia?
chronically impaired cognition that imapis multiple domains: memory, attention, language
What is the pathophysiology behind Alzheimers?
Neurofibrillary tagles and Beta Amyloid Plaques
What is the pathophysiology behind vascular dementia ?
Multiple infarcts
What is the pathophysiology behind lewy body dementia?
presence of lewy bodies in the occipito-parietal cortex
What is the pathophysiology behind frontotemporal dementia?
Pick bodies
What are the investigations for dementia?
MRI and cognitive function tests
What are the presentations of Alzheimers?
progressive, cognitive decline
Personality preserved
What is the presentation of frontotemporal dementia?
Disinhibition, personality change, early memory preservation, progressive aphasia
What is the presentation of vascular dementia?
Sudden onset, stepwise decline, patchy deficits
What is the presentation of Lewy Body dementia?
Fluctuating cognitive dysfunction, visual hallucinations, parkonsonism
How is alzheimers and lewy body dementia treated?
Cholinesterase inhibitors
