Dendritic Cell Flashcards
(6 cards)
Central to
- Antigen processing and presentation.
- stimulate adaptive immunity.
Immature dendritic cell migrate to antigen exposure, take up, migrate and mature to lymph node where they present antigen to B and T lymphocyte
This migrate process mediate by _________ and. ________
Adhesion molecule and chemotaxis
All tissue and organ contain dendritic cell but common in tissue cover body such as skin (____________) and in mucus membrane in elementary and respiratory system
langerhans cell
Most dendritic cell enter the lymph node via afferent lymphatic vessels in lymph fluid under influence of _______
Chemokine
Once in lymph node, dendritic cell localize in __________ area in vicinity of high endothelial venules, a site where naïve T lymphocytes enter the node. In this location dendritic cells _____________
Parafollicular
Active naive T lymphocyte
اشوف الصورة صفحة 12 تشابتر ٢
Special type of dendritic cell: function
Tolergenic dendritic cell
- suppress immune response by deletion of self reactive T lymphocyte