Lymphocyte Flashcards
(5 cards)
Lymphocytes are mobilized to the setting of any ______________ (i.e., infections) as well as ___________________ (e.g., due to infarction or tissue trauma).
specific immune stimulus
non-immune-mediated inflammation
Both T and B lymphocytes migrate into inflammatory sites using some of the same ______________ pairs and __________ that recruit other leukocytes.
adhesion molecule
chemokines
Lymphocytes and macrophages interact in a ___________ and these interactions play an important role in chronic inflammation.
Bidirectional way
How macrophage simulate lymphocyte in bidirectional way?
Macrophage display antigen to T cell, express membrane molecule (costimulators) produce cytokines (lL-12) stimulate T cell response
How lymphocyte simulate macrophage in bidirectional way?
Activated T lymphocyte produce cytokines (INF) is a powerful activator of macrophage, promoting antigen presentation and cytokine secretion.