Lymphocyte Flashcards

(5 cards)

1
Q

Lymphocytes are mobilized to the setting of any ______________ (i.e., infections) as well as ___________________ (e.g., due to infarction or tissue trauma).

A

specific immune stimulus
non-immune-mediated inflammation

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2
Q

Both T and B lymphocytes migrate into inflammatory sites using some of the same ______________ pairs and __________ that recruit other leukocytes.

A

adhesion molecule
chemokines

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3
Q

Lymphocytes and macrophages interact in a ___________ and these interactions play an important role in chronic inflammation.

A

Bidirectional way

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4
Q

How macrophage simulate lymphocyte in bidirectional way?

A

Macrophage display antigen to T cell, express membrane molecule (costimulators) produce cytokines (lL-12) stimulate T cell response

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5
Q

How lymphocyte simulate macrophage in bidirectional way?

A

Activated T lymphocyte produce cytokines (INF) is a powerful activator of macrophage, promoting antigen presentation and cytokine secretion.

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