Dental Pulp- Exam II Flashcards

(55 cards)

1
Q

What components can be found in mature dental pulp?

A

dentin
predentin
odontoblast layer
cell rich zone
pulpal core
pulpal dendritic cells

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2
Q

The dental pulp consists of ____ tissue derived from ____ cells.

A

loose connective tissue; neural crest (ectomesynchemal) cells

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3
Q

Mature dental pulp is divided into what two compartments?

A

Odontogenic zone and pulpal core

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4
Q

Odontoblast cell layer
cell-free zone of Weil
Cell-rich zone
Parietal plexus of nerves (Raschkow’s Plexus)
These are all components of:

A

Odontogenic zone of mature dentin

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5
Q

Fibroblasts
Type 1 and 3 collagen
Extracellular matrix
Blood vessels
Nerve tissue
These are all components of:

A

Pulpal core of mature dentin

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6
Q

The functions of the dental pulp include:

A
  1. embryonic induction
  2. Formative
  3. Protective
  4. Reparative
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7
Q

Cell populations in pulpal tissues include: (8)

A
  1. odontoblasts
  2. fibroblasts
  3. undifferentiated mesenchymal cells
  4. macrophages
  5. dendritic cells
  6. blood vessel related cells
  7. neural-related cells
  8. lymphocytes
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8
Q

The extracellular matrix of pulpal tissues incudes what type of collagen?

A

type 1, 3, 4 and 5

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9
Q

Non-collagenous matrix components of dental pulp include: (5)

A
  1. proteoglycans
  2. glycosaminoglycans
  3. phosphoproteins
  4. glycoproteins
  5. gamma-carboxyglutamate- containing proteins
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10
Q

The gamma-carboxyglutamate-contianing proteins include:

A
  1. BMP 2, 4 and 7
  2. fibroblast growth factor
  3. epidermal growth factor
  4. dentin matrix protein
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11
Q

Pulpal innervation includes both _____ and ____ nerve axons.

A

myelinated and unmyelinated

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12
Q

The pulpal innervation (axons) progressively branch, passing through the subodontoblastic layer as the _______.

A

parietal neural plexus

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13
Q

The parietal neural plexus may also be called:

A

Rashchows plexus

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14
Q

The pulpal axons progressively branch, passing through the subodontoblastic layer as teh parietal neural pelxus , on to the _____ cell layer and some fibers enter into ____.

A

odontoblastic cell layer; dentinal tubules

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15
Q

Most nerve endings in pulp are for:

A

pain

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16
Q

The nerve endings in pulp that are for pain are:

A

free nerve endings as sensory afferents from trigeminal nerve

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17
Q

A few nerve endings in the dental pulp are concerned with:

A

vasodilation and vasoconstricton

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18
Q

sensory afferents in the dental pulp come from:

A

trigeminal nerve (CN5)

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19
Q

Sensory afferents from the trigeminal nerve in the dental pulp include:

A
  1. pain
  2. mechanical (pressure)
  3. thermal (heat)
  4. tactile (touch)
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20
Q

____ branches from the superior cervical ganglion are primarily vasomotor fibers to pulpal blood vessels, concerned for the most part, with ____.

A

sympathetic; vasoconstriction

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21
Q

The majority of myelinated pulpal nerve axons in dental pulp are:

A

A-delta

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22
Q

A-delta myelinated pulpal nerve axons are:

A

fast conducting

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23
Q

What is the diameter range of a-delta myelinated pulpal nerve axons?

A

1-6 micrometers

24
Q

1 % of myelinated nerve fibers are classified as:

A

A-beta fibers

25
What is the diameter range of A-beta myelinated pulpal nerve fibers?
6-12 micrometers
26
Non-myelinated fibers are designated as ____ fibers and have small diameters, ranging from 0.4-1.2 micrometers
C fibers
27
Fibers that are associated with SHARP, localized pain:
A-delta fibers
28
Fibers that are associated with dull, diffuse pain
C fibers
29
Calcitonin gene-related peptide (CGRP) is a neuropeptide found in the dental pulp that function in:
vasodilation, and stimulates fibroblast cell division
30
Substance P is a neuropeptide found in the dental pulp that functions in:
vasodilation, and stimulates fibroblast cell division
31
Epinephrine is a neuropeptide found in the dental pulp that functions in:
vasoconstriction of smooth muscle
32
Norepinephrine is a neuropeptide found in the dental pulp that functions in:
sympathetic vasoconstriction
33
Dopamine is a neuropeptide found in the dental pulp that functions in:
Vasoactive or a precursor of epinephrine
34
Endorphin is a neuropeptide found in the dental pulp that functions in:
Silencer of nociceptors (silencer of pain)
35
List the neurotransmitters involved in dental pulp:
1. CGRP 2. Substance P 3. Epinephrine 4. Norepinephrine 5. Dopamine 6. Endorphin
36
Each nerve fiber in dental pulp contributes to to atleast _____ to Raschkow's Plexus
8 branches
37
Each nerve fiber contributes to atleast 8 branches to Raschkow's plexus. Most terminate in the plexus as:
free nonmyelinated nerve endings
38
The terminal capillaries in dental pulp ____ deep to the odontoblastic layer:
anastomose
39
Capillary loops are dense in the ____ and _____ and significantly less dense in the _____
coronal and pulp horns; radicular pulp
40
____ & _____ capillaries and _____ vessels are found in the pulp
continuous and fenestrated capillaries and lymph vessels
41
With aging, blood vessels in the pulp will exhibit changes such as:
cholesterol plaques (atherosclerosis)
42
If progressive and severe, atherosclerotic plaques can result in ______ due to vessel strangulation
pulpal hypoxia
43
______ leak serum that becomes a component of the so-called tissue fluid
fenestrated capillaries
44
Contributes to swelling and edema due to significant leakage of serum in states of inflammation
fenestrated capillaries
45
Occurs with increasing age or persistent low-grade injury (like multiple restorations in a single tooth, chronic bruxism, repeated thermal insult, etc.):
pulpal fibrosis
46
Irregular calcified deposits along collagen fiber bundles or within blood vessels resulting form chronic low-grade inflammation
diffuse calcifcations
47
Pulp stones may also be called:
Denticles
48
True pulp stones contain ____. False pulp stones feature concentric layers of _____ but are void of _____.
dentinal tubules calcified tissue; dentinal tubules
49
Classifications of pulp stones include:
1. free 2. attached 3. embedded
50
Defined as a dense aggregation of neutrophils and macrophages and other inflammatory cells within connective tissue under going liquefactive necrosis
pulpal abscess
51
What type of macrophages are found in pulpal abscesses?
1. vacuolated macrophages 2. syncytial macrophages or giant cells
52
What do the syncytial macrophages or giant cells in a pulpal abscess do?
resorb dentin adjacent to the inflamed pulp
53
Due to the inability of pulpal tissue to swell, the increasing edema and inflammatory cell infiltration will eventually lead to ____, that in turn is expressed clinical by _______ and _____ of the PDL and associated alveolar bone
pulpal necrosis persistant pain; periapical necrosis
54
Seen on dental radiographs as a radiolucent area associated with the apex of the involved tooth:
periapical necrosis
55
Treatment for a periapical abscess would include:
I & D