Odontogenesis- Exam 1 Flashcards
(105 cards)
1
Q
What 4 components make up the tooth?
A
enamel, dentin, cementum, pulp
2
Q
What 4 components make up the periodontium?
A
ginigiva, periodontal ligament, cementum, and alveolar bone proper
3
Q
List the 6 stages of tooth development?
A
- initiation
- bud stage
- cap stage
- bell stage
- apposition
- maturation
4
Q
During the initiation stage of tooth development what occurs?
A
cellular induction
5
Q
During the bud stage of tooth development, what occurs?
A
cellular proliferation
6
Q
During the cap stage of tooth development, what occurs?
A
proliferation, differentiation, and morphogenesis
7
Q
During the bell stage of tooth development, what occurs?
A
proliferation, differentiation and morphogenesis
8
Q
During the apposition stage of tooth development, what occurs?
A
induction and proliferation
9
Q
During the maturation stage of tooth development, what occurs?
A
maturation
10
Q
What plays an instructional role during the pre-tooth bud stage of tooth formation?
A
epithelium (ectoderm)
11
Q
What dictates what type of tooth will be formed?
A
neural crest cells (mesenchyme)
12
Q
The enamel organ is derived from:
A
primitive oral ectoderm
13
Q
What 3 structures are prominent during the induction stage of tooth development?
A
- oral ectoderm
- neural crest cells
- dental lamina
14
Q
When does the induction stage of tooth development occur?
A
6-7th week
15
Q
During the induction stage, when the ectoderm invaginates into the mesenchyme, it can now be referred to as:
A
dental lamina
16
Q
THe dental lamina is separated from the surrounding mesenchyme by a:
A
basement membrane
17
Q
When does the bud stage of tooth development occur?
A
8th week
18
Q
During the bud stage of tooth development, the proliferating oral ectoderm makes the transition into:
A
dental lamina
19
Q
When does the early cap stage of tooth development occur?
A
9-10 weeks
20
Q
During the early cap stage ____ occurs resulting in the creation of buccal vestibule
A
apoptosis
21
Q
What help to hold the shape of the enamel organ during the cap stage
A
stellate epithelium
22
Q
cells that are still undifferentiated but make their way up into the inner enamel epithelium area:
A
dental papilla
23
Q
Some of the dental papilla cells will end up becoming:
A
odontoblast & pulp
24
Q
During the cap stage of of tooth development, what surrounds the enamel organ, inner enamel epithelium and dental papilla?
A
dental follicle
25
The dental follicle may also be called:
dental sac
26
The dental follicle encapsulates the entire enamel organ and will eventually become the:
periodontal ligament, cementum, and alveolar bone
27
At this stage, all layers of the enamel organ can be differentiated:
bell stage
28
During the bell stage, the inside of the enamel organ is comprised of:
inner enamel epithelium
29
During the bell stage, the enamel organ is covered by ____ on the outside
outer enamel epithelium
30
The double layer of flattened cells on top of the inner enamel epithelium during the bell stage:
stratum intermedium
31
During the bell stage, the loosely packed cells on the inside of the stratum intermedium:
stellate reticulium
32
The rounded cells lining the basement during the bell stage:
pre-odontoblasts
33
The outer enamel epithelium is comprised of ___ cells and serves as ____.
cuboidal cells and serves as a protective barrier
34
The inner enamel epithelium is comprised of ____ cells and differentiates into:
cuboidal cells; ameolblasts
35
The stellate reticulum are ____ shaped cells forming the network inside the _____.
star-shaped; enamel organ
36
What serves as the supportive function in enamel production:
stellate reticulum & stratum intermedium
37
The stratum intermedium is a compressed layer of _____ cells
flat cuboidal cells
38
The dental sac consists of ____ fibers around the ____
collagen; enamel organ
39
What will the dental sac eventually differentiate into?
1. cementum
2. PDL
3. alveolar bone
40
The cells nearest to the IEE that have basement membrane separation:
dental papilla
41
The outer cells of the dental papilla differentiate into:
odontblasts
42
The inner cells of the dental papilla differentiate into:
pulp tissue
43
During the bell stage at the bottom where the inner and outer enamel epitheliums meet form the:
cervical loop
44
During root development, the junction of the outer and inner enamel epithelia
cervical loop
45
The cervical loop is the site of _____ in the adult tooth
cemento-enamel junction (CEJ)
46
Fusion of the apical extension of the outer and inner enamel epithelia
Hertwig's epithelial root sheath
47
What determines the outline of the root dentin and the number of roots a tooth will have?
hertwig's epithelial root sheath
48
Hertwig's epithelial root sheath is removed before the _____ is laid down
cementum
49
Enamel formation stops at the termination of the:
enamel organ
50
Enamel formation stops at the termination of the enamel organ but ____ continues and pushes the tooth ____.
dentin formation; occlusally
51
The epithelial diaphragm is the modification of the Hertwigs sheath creating septa that divide into the ____ and create ___.
pulpal tissue; multiple roots
52
Root lenght is not complete until ____ after the tooth is emerged into the oral cavity
1-4 years
53
After the tooth is emerged into the oral cavity, what happens with the roots?
pulp chamber narrows and apical opening constricts
54
What type of growth describes tooth development?
appositional growth
55
During the apposition stage of tooth development, the stratum intermedium produces:
alkaline phosphatase
56
During the apposition stage, the inner enamel epithelium will form _____ which will form ____
ameloblasts; enamel
57
During the apposition stage of tooth development, the peripheral cells of the dental papilla form the ___ which will form the ____
odontoblasts; dentin
58
What is the first formed dentin called?
mantle dentin
59
Mantle dentin contains what types of collagen?
type 1 and type 3
60
In the mantle dentin, the collagen fiber in the matrix are oriented ____ to the DEJ
perpindicular
61
The presence of the mantle dentin stimulates the _____
ameloblasts to secrete the enamel matrix
62
During the apposition stage of tooth development, the ameloblasts migrate ____ while the odontoblasts migrate ____.
ameloblasts- peripherally
odontoblasts- inward (centrally)
63
Describe actively secreting ameoloblasts:
tall columnar cells
64
Describe inactive ameloblasts:
short columnar or elongated cuboidal cells
65
At the final stage of mineralization, the reduced ameloblasts with the remaining cells of the outer enamel epithelium, stellate reticulum, and stratum intermedium form a membrane on the surface of the enamel. This is termed:
primary cuticle
66
The primary cuticle may also be called:
nasmyth's membrane
67
What are the 4 abnormal tooth development categories?
1. anodontia
2. hypodontia
3. oligodontia
4. hyperdontia
68
Refers to the total lack of tooth development
anodontia
69
Refers to the lack of development of one or more teeth
hypodontia
70
Refers to the lack of formation of six or more teeth (a subdivision of hypodontia)
oligodontia
71
Refers to the development of an increased number of teeth (the additional teeth are termed supernumerary)
hyperdontia
72
Defect that originates during the initiation stage that results in development of one or more extra teeth
supernumerary teeth
73
What stage do supernumerary teeth develop in?
initiation stage
74
The most common manifestatio of supernumerary tooth formation
mesodens
75
Results in multiple small fragments of tooth structure consisting of dentin, enamel, cementum or any combination. This occurs during the initiation stage
odontoma
76
What stage does odontoma occur in?
initiation stage
77
Comprised of a conglomerate mass of enamel and dentin that bears no anatomic resemblance to a tooth
complex odontoma
78
Comprised of multiple, small tooth-like structures
compound odontoma
79
An enlargement of the body and pulp chamber of multi-rooted teeth with apical displacement of the bifurcation (for example an exceptionally long root trunk with very short roots)
taurodontism
80
Defined as an abnormal angulation or bend in the root
dilaceration
81
defect that originations during cap stage of development that results in large single-rooted tooth with one pulp cavity and exhibits twinning in crown area
gemination
82
During what stage of tooth development does gemination take place?
cap stage
83
Tooth count is normal when the double tooth is counted as one in this form of abnormal tooth development:
gemination
84
Refers to a double tooth in which the tooth count reveals a missing tooth when the double tooth is counted as one:
fusion
85
Defect occurring during the apposition and maturation stages that results in union of root structure of two or more teeth by cementum
concresence
86
Defect occuring during the cap stage of development that restults in an extra cusp due to effects on enamel organ
tubercle formation
87
During what stage of tooth development does concresence occur?
apposition and maturation stage
88
During what stage of tooth development does tubercle formation occur?
Cap stage
89
Originates by separation of the dental follicle (dental sac) from the crown of an unerupted tooth.
Dentigerous Cyst (a.k.a follicular cyst)
90
A dentigerous cyst is attached at the:
CEJ
91
Comprises 20% of all jaw cysts
dentigerous cyst
92
Arises from the cells rests of the of dental laminal (also called rests of serres)
Keratocystic odontogenic tumor
93
The OKC constitutes _____ of all odontogenic cysts
3- 11%
94
60% of all odontogenic keratocyst cases are diagnosed in patients between the ages of:
10-40 years
95
OKCs are considered _____ cysts
bone expanding
96
OKs located in the posterior mandible often present as:
multilocular lesions
97
What is the treatment of choice for an OKC
surgical removal
98
What occurs 30% of the time after the surgical removal of an OKC?
recurrence
99
In an OKC, wall consisting of a 6-8 cell layer of stratified squamous epithelium with ____ at the luminal surface
parakeratosis
100
The lumen of an odontogenic keratocyst (OKC) if often filled with:
keratin
101
IN and OKC presence of inflammaton will generally cause epithelial ____ & ____ of the basal cell layer
proliferation and pallisading
102
The most common neoplastic lesion arising from odontogenic epithelium.
amelobastoma
103
What type of epithelium does an ameloblastoma arise from?
odontogenic epithelium
104
Considered a slow growing, locally invasive tumor that has a multilocular or "soap bubble" appearance on radiographs.
ameloblastoma
105
Ameloblastomas are _____ when it comes to radiation
radio-resistant
