Depression Flashcards
(22 cards)
What are the 2 core symptoms and for how long do they need to be present for
Low mood
Anhedonia (lack of pressure or interest in activities)
For 2 weeks
What does the mental health act 1983 allow
Compulsory admission for people who need to be admitted for their or safety or the protection not others
Mild depression management
CBT
Mod to server
Antidepressants + CBT
1st line in mod to severe
Non pharamcooogical +
SSRI
• fluoxtine(preferred in children)
• sertraline
• citalapram
2nd line
SNRI
• duloxetine
• venlafaxine
TCA
• amitriptyline
Which drugs should be avoided due to potential risk of toxicity if the person is at risk of suicide
TCA + venlafaxine
How long can it take for drug to work
4 weeks
What symptoms may they experience during these weeks
Agitation
Anxiety
Depression getting worse
Suicidal thoughts
Which in how long should patients be reviewed when starting
1 week
How long after treatment should the drug be continued to prevent replace
6 months
SSRI moa
Block serotonin transporter
Increasing zeros in levels in the synaptic cleft
SNRI moa
Inhibits serotonin and norephrine transporters increasing their levels in the synaptic cleft
TCA mod
nhibits serotonin and norephrine transporters increasing their levels in the synaptic cleft
Drug interactions with NSAIDs
SSRIs or SNRIs - increase gi bleeding risk
Drugs which interact with triptans
SSRIs - seritonin syndrome
TCA can also block which receptor
M1 - muscarininc
H1 - histamine
Alpha 1
Blocking M1 - muscarininc will cause which side effects
Confusion
Dry mouth
Constpation
Urinary incontinence
Blurred vision
Blocking H1 - histamine will cause
Sedation
Weight gain
Blocking alpha 1 will
Orthstatic hypotension
After how long should antidepressant be continues if on due to relapse
2 years
Mirtazpine is a aytipical antidepressant, what are the ADRs
Sedation and weight gain
