Depression and mood disorders Flashcards
(23 cards)
define reactive depression
triggered by a negative experience
define endogenous depression
no apparent negative life event
define unipolar affective disorder
depression
define bipolar affective disorder
depression with periods of mania
mania
energetic, impulsive, positive, very confident
unipolar affective disorder incidence
5-17%
bipolar affective disorder incidence
1% incidence
what is the concordance rate for monoxygotic twins (depression)
39%w
what is the depression concordance rate for dizygotic twins
27% concordance rate
what is the diathesis stress model
risk factor genes + stress -> depression
mono amine oxidase inhibitors
monamines -> catecholaines -> dopamine, epinerphrine, norepinephrine
monamines-> indolamines-> seretonin
N.B epinephrine
adrenaline
norepinephrine
noradrenaline
seretonin
5HT
what is mono amine oxidase inhibitors
an enzyme that breaks down monamine neurotransmitters
what do tricyclic antidepressants do
block reuptake and therefore leaves more transmitter at the synapse
what does prozac do
blocks reputake and therefore leave more transmitter at the synapse
prozac is a
selective seretonin re-uptake inhibitor
what is used to treat bipolar disorder
interferes with second messenger system
monoamine theory of depression
depression is actually caused by a deficit of monoamine neurotransmission
becks cognitive triaf
-negative views about the world
-negative views about onseself
-negative viewsa about the future.
seligman’s attribiutional model - 3 dimensions of negative events
internal vs external
global vs specific
stable vs unstable
rumination
dwelling
