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Flashcards in depressive disorders Deck (18):
1

hx of one of more depressive disorders and no hx of manic or hypomanic episodes

Major Depressive Disorder (MDD)

2

For a diagnosis of MDD, 5 or more of which symptoms need to be present during the same 2 week period?

- depressed mood
- anhedonia
- significant weight loss or gain
- insomnia or hypersomnia
- change in motor activity
- anergia

3

For Dysthymic Disorder (DD), a depressed mood needs to occur over what timeframe for adults and children/adolescence?

-adults: over 2 yrs
- children/adolescences: over 1 yr

4

Presence of two or more of which symptoms needs to occur for a diagnosis of DD?

- change in appetite
- insomnia or hypersomnia
- anergia
- decreased self-esteem
- decreased concentration or indecisiveness
- feelings of hopelessness or despair

5

duration of tx of depressive stages?

1) Acute (6-12 wks)
2) Continuation (4-9 months)
3) Maintenance ( > 1 yrs)

6

1st Line meds for depression?

1) SSRI's (first choice)
2) newer atypical antidepressants
3) Tricyclic Antidepressants

7

2nd Line meds for depression?

- MOAI's
- ECT

8

SSRI's are the 1st line tx for all types of depression except for?

psychotic depression

9

1st line tx for all types of depression except of psychotic depression?

ECT

10

Common A/E's of SSRI's?

- sexual discomfort
- weight gain (rare)
- minimal sedation

11

Potential toxic effects of SSRI's?

- central serotonin syndrome (rare and life threatening)

12

SSRI's should be stopped how long before starting an MOAI?

2-5 weeks

13

TCA that is a good choice for the elderly because of its low side effect profile and its rapid effect on promoting sleep?

Trimipramine (surmontil)

14

Mood elevation with a TCA may take ________ and the full effect occurs _____________?

- 7-28 days
- 6-8 weeks

15

side effects of TCA usually subside after?

first few weeks

16

common A/Es of MOAI?

- orthostatic hypotension
- weight gain
- edema
- change in cardiac rate/rhythm
- constipation
- urinary hesitancy
- vertigo
- sexual impotence
- insomnia, weakness and fatigue

17

tell patients taking MOAI's to report to the ER if they experience?

a severe headache

18

Patients should maintain dietary precautions for how long after stopping MAOI's?

14 days