depressive disorders Flashcards
hx of one of more depressive disorders and no hx of manic or hypomanic episodes
Major Depressive Disorder (MDD)
For a diagnosis of MDD, 5 or more of which symptoms need to be present during the same 2 week period?
- depressed mood
- anhedonia
- significant weight loss or gain
- insomnia or hypersomnia
- change in motor activity
- anergia
For Dysthymic Disorder (DD), a depressed mood needs to occur over what timeframe for adults and children/adolescence?
- adults: over 2 yrs
- children/adolescences: over 1 yr
Presence of two or more of which symptoms needs to occur for a diagnosis of DD?
- change in appetite
- insomnia or hypersomnia
- anergia
- decreased self-esteem
- decreased concentration or indecisiveness
- feelings of hopelessness or despair
duration of tx of depressive stages?
1) Acute (6-12 wks)
2) Continuation (4-9 months)
3) Maintenance ( > 1 yrs)
1st Line meds for depression?
1) SSRI’s (first choice)
2) newer atypical antidepressants
3) Tricyclic Antidepressants
2nd Line meds for depression?
- MOAI’s
- ECT
SSRI’s are the 1st line tx for all types of depression except for?
psychotic depression
1st line tx for all types of depression except of psychotic depression?
ECT
Common A/E’s of SSRI’s?
- sexual discomfort
- weight gain (rare)
- minimal sedation
Potential toxic effects of SSRI’s?
- central serotonin syndrome (rare and life threatening)
SSRI’s should be stopped how long before starting an MOAI?
2-5 weeks
TCA that is a good choice for the elderly because of its low side effect profile and its rapid effect on promoting sleep?
Trimipramine (surmontil)
Mood elevation with a TCA may take ________ and the full effect occurs _____________?
- 7-28 days
- 6-8 weeks
side effects of TCA usually subside after?
first few weeks
