Depressive Disorders, Weiss Flashcards Preview

Year 2 Psych exam I > Depressive Disorders, Weiss > Flashcards

Flashcards in Depressive Disorders, Weiss Deck (32):
1

depressive disorders more common in M or W

W

2

age onset depresstion

40 y.o average

3

cause depression

unknown

4

causative factors for depression

biological
genetic
pyschosocial

5

biological factors for depression

dysregulation with NT
neuroendocrine dysregulation of adrenal or thyroid axis
growth hormones etc

6

genetic factors for depression

pattern unknown
1st degree relatives 2-10 x more likely
50% monozygotic twins

7

psychosocial factors for depression

stressful events
premorbid personality factors
learned helplessness
cognitive theory
psychodynamic theory
early childhood trauma

8

what is dysthymia

peristent depressive disorder that is chronic low grade
does not respond well to antidepressants

9

tyeps of depressive disorders

major, single
major, recurrent
persistent depressive disorder
substance. med induced
premenstrual dysphoric disorder
depressive from another medical condition

10

Dx depression

significant distress with funcitonal impairment
not due to direct physiological effects of a substance

11

major depressive disorder

at least a depressed mood or anhedonia(lack of interest of pleasurable activity)
at least 2 weeks
at least 4 Sx

12

clinical features depression

depressed mood
marked dec interest
dec/inc appetite, weight change
sleep disturbance
psychomotor agitaiton/retardation
loss of E
guilt, worthlessness
poor concentration, indecisiveness
recurrent thoughts of death, suicidal thoughts

13

mental status exam general description

appearance, hygiene
level cooperativeness
eye contact
posture
pyschomotor agitation/retardation

14

mental status exam

speech
perceptual disturbances
thought content
suicidal thoughts
orientation
memory
concentration
attention
judgement, insight, reliability

15

what general medical conditions can lead to depression

infections, endocrine disorders, inflammatory disorders, neuro disorders, vitamine deficiencies
neoplasms

16

course of depression

chronic relapsing

17

poor pronostic indicators for depression

coexisting dythymic disorder, alcohol abuse, anxiety disordesr, multiple episodes, hospitalizaiton, men, poor support, late age initial onset, personality disorder, psychotic component

18

first decision when Tx depressed patient

safety
do need to hospitalization, at risk of self?

19

risk factors for suicide

male
elderly
caucasian
Hx previous attempts
co morbic medical illness
drug/alcohol abuse
comorbid psych illness
social isolation
low job satisfaction, financial stress

20

risk factors for suicide

male
elderly
caucasian
Hx previous attempts
co morbid medical illness
drug/alcohol abuse
comorbid psych illness
social isolation
low job satisfaction, financial stress

21

Tx for depression

hospitalization vs outpatient
complete Diagnostic eval
establish plan
psychosocial therapies

22

pharmacotherapy depression

TCA, SSRI, SNRI, MAOI, bupropion, mirtazapine, atypical antipsychs, augmenting: lithium, thyroid, stimulants and combinations

23

what TCA are used in depression

nortriptyline
amitriptyline
imipramine
desipramine

24

SSRIs for depression

fluoxetine
paroxetine
sertraline
citalopram
escitalopram
fluvoxamine

25

what is first line for depression

SSRI

26

MAOI for depression

phenelzine
selegiline
tranylcypromine
isocaroxazid

27

SNRI used in depression

venlafaxine
duloxetine
desvenlafaxine

28

side effect venlafaxine

HTN

29

Bupropion

dec seizure threshold significantly
no sexual dysfunction with this drug

30

mirtazapine

great for elder woman not eating or sleeping
no sexual dysfunction

31

lithium warning

can overdose easily, low therapeutic index

32

major side effects of antidepressants

GI
sexual
withdrawal flu
weight gain
seizure threshold
HTN
sedation/stimulation