Derm Flashcards
1
Q
Linear crusted leisons a few milimeters in length and intense itching pathognomic of? Usual locations? Rx
A
Scabies
Webbing of fingers / toes and nipples
Permethrin
2
Q
Single very itchy area with serpiginous (wavey) tracks? Caused by? Most common body part?
A
Cutaneous Lava migrans
Hookworm
Foot
3
Q
BCC prognosis post excision?
A
100% -
[Usually takes over 5 years to met]
4
Q
Most common skin Ca? What does it look like
A
BCC
-Ulcer with a rolled edge
-Prominent fine blood vessels around edge
- Pearly / waxy nodule on skin
5
Q
Suspected BCC referral speed?
A
Can be routine rather than usual urgent for Ca
6
Q
What is Imiquimod?
A
Topical Rx option for BCCs
7
Q
What is Vismodegib used for?>
A
Used for Rx of metastatic BCCs
[Targets hedgehog pathway signaling]
8
Q
Surgery for BCC called
A
Mohs - Gets complete margin control
9
Q
Tense itchy blisters in pregnancy? Basic Ix rx
A
Pemphigoid of pregnancy
Skin biopsies + immunofluorescence
Oral pred if bad
10
Q
Urticated and plaques which are very itchy in pregnancy and SPARING umbilicus
A
Polymorphic eruption of pregnancy
11
Q
Bullos pemphigoid description? Antibodies? Usual Ix/Rx? If bad?
A
Tense blisters
IgG Hemidesmomosal [BP180/BP230]
Biopsy + immunofluorescence
Oral pred
[Add Azathioprine / cyclosporin /mycophenolate]
11
Q
Bullos pemphigoid description? Antibodies? Usual Ix/Rx? If bad?
A
Tense blisters
IgG Hemidesmomosal [BP180/BP230]
Biopsy + imunoflourescence [and blood imunoflourescence] will show IgG/C3 deposition
Oral pred [Add Azathioprine / cyclosporin / mycophenolate]
12
Q
Cafe-au-lait patches + armpit freckles ? chromosome? When do these lesions get more pronounced and why?
A
Neurofibromatosis type 1
Chromosome 17 - Dominant inheritance
In pregnancy as usually oestrogen responsive
13
Q
How is NF2 different to NF1? Characteristic finding? Chromosome
A
NF2 usually has CNS Lesions eg. swhanomas / meningiomas
Bilateral acoustic neuromas -> Tinnitus/deafness/vertigo
Chromosome 22 [for NF2]
14
Q
Facial angiofibromas, periungual (toe/finger nail) fibromas and ‘ash leaf spots’?
How to see these best?
A
Tuberous sclerosis
Woods ultraviolet lamp
15
Q
Small brown nodules on iris seen in what? called?
A
NF1
Lisch nodules - seen on slit lamp
16
Q
Excoriated symmetrical papules on extensor surfaces of knees elbows, buttocks and back?
Commonly associated with?
Gene?
Diagnostic tests?
Rx?
A
Dermatitis herpetiformis [nothing to do with herpes]
Coeliac. Both are due to a gliardin [gluten] allergy
HLA DQ2, HLA DQ8
TTG antigen + skin biopsy [will show microabscesses in dermal papillae, granular IgA deposits]
[Can use endomysial antibody if TTG weakly positive]
Gluten free diet
Oral dapsone
17
Q
Dematitis herpetiformis and don’t stick to gluten free diet risk developing?
A
Non Hodgkin lymphoma
18
Q
Most common antibody in SLE? 2 others that are more specific but less sensitive?
A
Anti nuclear antibody
Anti-Ds DNA
Anti Sm
19
Q
Anti-ccp antibody
A
Rheumatoid arthritis
[Present in 50-75%, indicates more agressive disease]
20
Q
An anti-mitochondrial antibody found in?
A
Primary biliary cholangitis (90%)
Also found in SLE, though less frequent
21
Q
Anti-smooth muscle antibody? other thing found in this condition?
A
Autoimmune hepatitis
IgG predominant polyclonal HyperGammaGlobulinaemia [found in 85%]
22
Q
Rx rosacea
A
Topical metronidazole / azeliac acid
[can use oral tetracycline
Resistant cases may need isotrenatoin]
23
Q
Bromonidine gel used for
A
Severe rosacea
24
Anti-ribosomal P antibodies in?
Cerebral SLE
25
cANCA ? common features with this
Granulomatosis with polyangitis
Sinusitis, renal vasculitis, mononeritis
Pulm haemorrhage later in disease
26
Super common DMARD in SLE arthritis
Hydroxychloriquine
27
Recurrent arterial / venous thrombosis + fetal loss
Antiphospholipid syndrome
28
Endocarditis / focal neurological lesions in lupus usually have which antibody
Anti-phospholipid
29
In SLE what does low C3/C4 levels indicate
Lupus nephritis
30
SLE with vital organ involvement Rx ? If refractory disease?
Steroids + immunosupression
[Azathioprine / methotrexate]
Plasma exchange + ritixumab
31
Yellow papules on skin [usually on neck]- looks like a plucked chicken?CV findings? Were else does it affect?
Pseudoxanthoma elasticum
Skin, Eyes, Cardiac
[Does sometimes give GI bleeding too!]
Mitral valve prolapse
Premature CV disease Eg CAD/claudication
32
What might you see in eyes of someone with Pseudoxanthoma elasticum? skin ?
Angiod streaks [dark red streaks by retinal vessles]
-> visual loss
Skin looks yellow and like plucked chicken
33
Symmetrical skin pigmentation on cheeks in women is called and usually seen in?
Melasma
Pregnancy
34
Target lesions (concentric rings) ? most commonly seen in?
Erythema multiform
Infection - Herpes/mycoplasma most common
[Also seen as a drug reaction some times - eg valproate, penicillin]
34
Target lesions (concentric rings) ? most commonly seen in?
Erythema multiform
Infection - Herpes/mycoplasma most common
[Also seen as a drug reaction some times - eg valproate, penicillin]
35
Pathogen causing a red, tender skin leison with induration and a sharply defined, rapidly progressing border
Strep pyogenes
Group A Beta haemolytic strep
36
ANIMALS in history -> Bald patch on scalp increasing in size caused by?
If no animals in history?
Rx of tinea capits?
Microsporum canis
Trichophyton tonsurans
[Both fungal infections causing tinea capitis]
Systemic antifungals
37
Microsporum canis characteristic finding on woods lamp?
Bright green fluroescence
38
What is Onychomycosis
fungal infection of nail
39
Key Ix if people have recurrent fungal infections
GTT
- as often the presentation of diabetes
40
pulmonary infiltrates + Halo sign on CT
Aspergillous
41
Cryptococcal meningitis. Staining on CSF?
India staining
42
Annular erythematous lesion with overlying scaling seen in?
Tinea Corporis
43
Recurrent skin infections usually mean s. aureus is producing what?
PVL
44
Staph aureus produces what in rapid bad food poisoning?
Enterotoxin
45
Toxic shock syndrome means s. aureus is producing what?
TSST-1
46
S Aureus producing these things usually leads to what?
1- PVL
2- Enterotoxin
3- TSST-1
1- PVL - recurrent skin infections
2- Enterotoxin - food poisoning
3- TSST-1 - toxic shock
47
Sandfly bite -> which infection? Usually presents as? Rx?
Leishmaniasis
Solitary ulcer
Sodium Stibogluconate
48
visceral leishmaniasis always has what?
Hepatosplenomegaly
49
Itchy flat topped papular rash on wrists and ankles. White 'lacy' or lined pattern of rash [often in mouth] is called what?. What is koebner phenonomen?
Lichen plannus
Whickam's striae
Where rash colonises site of trauma a few days later
50
Vesicular eczema which affects soles, palms and fingers
pompholyx
51
Management of lichen planus
Topical steroids / tacrolimus
Oral steroids if bad
->UVB phototherapy / dmards
52
Plum coloured skin lesions [usually in haem onc]
Sweet's syndrome
[sweet plums]
53
What is bowens disease
Slow growing scaly erythematous patches related to long term sun exposure
[may progress to SCC]
54
What are actinic keratosis
rough patches often itchy related to sun exposure
55
What is 5-flurorouracil cream used for
actinic keratosis or bowens
[Usually just cut them out if needed / cryotherapy]
56
Melanoma found on sole of the foot / pam ?
Acral lentiginous melanoma
[ACRA i just stood on something]
57
Most common melanoma
superficial spreading
58
Dark pigmented melanoma? found where ?
Nodular
Usually agressive and fast growing
Usually on legs/ trunk
59
Slowly expanding irregularly pigmented macule usually found in older people
Lentigo maligna melanoma
60
How does melanoma metastasise
through lymph
61
What determines prognosis of melanoma
breslow thickess
62
Lesions which usually found on legs start as papules/pustules which then breakdown into painful necrotic ulcers
Pyoderma gangrenosum
63
Bar legs where is a common place to get pyoderma gangrenosum
By stoma sites in pts with IBD
64
Differentiate PBC and PSC
Both have obstructive LFTs
PBC - anti-mitochondrial antibodies
PSC - link to IBD
65
PBC, how to confirm diagnosiss? initial therapy?
Liver biopsy (+anti-mitochondrial antibody)
ursodeoxychoic acid
[can add obeticholic acid if not working]
May need liver transplant in long run
66
clustered pearly papules with a central umbilicus. Often found in kids and immunocompromised? caused by? Usual Rx
Molluscum contagosum
pox virus
No treatment in immunocompetent
67
Photosensitive dermatitis, diarrhoea and dementia=? Cause?
What is the common cause of the cause?
Rx?
Pellagra
Due to niacin (vit D3) deficiency [DDD due to D3 deficiency]
Carconoid syndrome
[Serotonin production -> negative feedback on D3 production]
Niacin replacement
Rx of carcinoid eg somatostatin analogue Eg ocretide
68
Dermatitis lesions which appear overnight. Especially if Hx of self harm or psychiatric
Dermatitis artefacta
69
Viral infection -> large scaly oval patch -> similar smaller patches
Pityriasis rosea
70
Purpuric rash on buttocks and lower legs. Abdominal pain and vomiting (+/- GI bleed)? Usual age? Any other features? Management?
Henoch-schonlein-purpura
Usally 15-19 years old
Usually get renal involvement (nephritis / nephrotic syndrome)
Usually triggered by a respiratory infection
Usually supportive but may need pred
71
What is deposited in affected organs and raised in HSP?
IgA
72
Purpuric rash in HSP - what are the platelets saying?
Normal. Purpuric rash is not due to thrombocytopenia
73
Drug for dermatitis herpetiforms
Dapsone
74
3 classes of drug that exacerbate psoriasis
B blockers
Antimalarials
Lithium
75
Streptococcal infection leads to which classical rash
Guttate psoriasis
76
What does pustular psoriasis look like? Key association with pustuar psoriasis on palms / soles?
Sheets of small yellow pustules on a red background
Smoking
77
What does guttate psoriasis look like? Key association?
Acute eruption of drop like leisons
Streptococca infection
78
What happens to psoriasis during preg and post partum?
Gets better in pregnancy
Worse post partum
79
Name a few topical options for psoriasis
Coal tar - useful for thick plaque psoriasis
Dithranol
Vit D analogues
Taraztoene - Retinoid (think TARAtogenic)
Steroids
80
Vid D analogue name
Calcipotriol
81
What is second line (after topical) for Rx of psoriasis?
When is it recommended first line?
Phototherapy
If >10% BSA, Nail bed psoriasis, or general high stress Eg question mentions someone going wild as they've got psoriasis face
82
First line DMARD for psoriasis? What do you have to monitor 3 monthly?
DMARD if for short term or need rapid control?
Methotrexate (Blocks DNA synthesis)
P3NP - Used to monitor liver fibrosis
[Psoriasis3NonthlyPlease]
Ciclosporin (inhibits t-lymphocyte transcription of IL-2)
83
Key side effects of ciclosporin
Renal toxicity
Hypertension
84
Odd thing to monitor with retanoids Eg acitretin? Another common side effect
Triglyceride levels
Mucocutaneous side effects
85
Biologics are 3rd line psoriasis. name a -mab that is given as an infusion? Sub cut? how to they work?
INFliximab - INFusion
Adalibumab - Sub cut
TNFa inhibitors
86
How does etanercept work?
Human protein fusion of the TNF receptor
Binds to TNFa and blocks it
[given sub-cut]
87
Name a couple key associations with psoriasis longer term....
CV - Eg MI / Stroke / Venous thromboembolism
Athropathy
Gout
Lymphoma
Skin Ca (not melanoma)
Malabsorbtion - UC / Crohns
88
Nails have a green discolouration means what infection?
Pseudomonas
89
What is Onycholysis? Key associations?
Nail separates from nail bed
Psoriasis
Fungal
90
Nail Onycholysis, pustual, hyperkeratosis =
psoriasis
91
Nail onycholysis, discolouration, thickening =
Fungal
92
Nail thinning, longitudinal depressions
Lichen planus
93
Nail pitting, thickening and ridging (sandpaper nail)
Alopecia areata
94
Nail onycholysis, coarse pits, cross-ridging
Dermatitis
95
Name 3 things that cause koebner phenomenon
Psoriasis
Lichen planus
vitiligo
warts
Molluscum contagiosum
95
Name 3 things that cause koebner phenomenon. what is it?
Psoriasis
Lichen planus
vitiligo
warts
Molluscum contagiosum
These things develop over areas of trauma
96
What is erythroderma
Severe skin inflammation covering most of body
97
Itchy small blisters. Biopsy shows IgA immunoflourescene =
Dermatitis herpetiformis
98
Monitoring with dapsone ?Used for
Can cause polyneuropathy, haemolysis + liver issues
Monitor bloods + LFTs
Dermatitis herpetiformis
99
General pathology of inflam plaque in psoriasis
Activated T-Lymphocytes into the epidermis
->Activate keratinocytes
-Get upregulation of TNFa, IL-2 and Interferon gamma
100
Which IL key in psoriasis? Gout / Stills?
IL-17 / IL-22- psoriasis
[Don't forget TNFa of course]
IL-1 - gout and stills
101
Key risks for amiodarone>?
Photosensitive
Hepatic / pulm fibrosis
Thyroid disorders
102
3 parts of melanoma that actually change prognosis
Thickness
Ulceration
Lymph node micrometastisis
103
Red / violaceous [violet] periorbital rash
Papules over knuckles
Nail fold inflammation
Proximal myopathy [rarely involuntary muscles Eg swallowing]
=?
Which antibody is diagnostic?
Common association? Drug association?
Dermatomyositis
Anti-Mi-2 [ONLY found in 30%)
Many have an underlying Ca
Penicilliamine
104
Anti-jo-1 found in? Key association?
Polymyositis
Pulmonary fibrosis
105
Rx dermatomyositis
Pred
Aza/ciclo if not repsponding
106
What is cheiroathropathy ?
Arthropathy associated with long-term diabetes and microvascular complications
-> Frozen shoulder / carpal tunnel
->Thickened swollen skin over fingers
107
Questions mentions decades history diabetes and thick skin
cheiroathropathy
108
pencil-in-cup deformity on XR
Psoriatic athropathy
109
2 most common causes of erythroderma ? What is it?
Psoriasis
Eczema
General term for any inflammatory skin condition which affects >90%
[Others include drug eruption / pityriasis rubra pilaris / cutaneous lymphoma]
110
photosensitive blistering rash commonly triggered/ sustained by alcohol? Other triggers? Apart from avoiding sun/ using suncream what is the mainstay of Rx? drug you can sometimes use?
Porphyria cutanea tarda (PCT)
Oestrogen, HepC, HIV
Phlebotomy to avoid Porphyrin deposits in liver- guided by ferritin levels
Hydroxychloroquine
111
Porphyria cutanea tarda (PCT) - how to spot the pathogenesis if in question
deficinecy of uroPORPHYIN decarboxylaze.
Ie the answer is there....
[Investigations also are for serum/urinary PROPHYRINs -these make urine red]
112
first line (if Non topical) management of rosacea?
Oral tetracycline
113
Erythema nodosum sometimes idiopathic... Name a few associations
IBD
Sarcoid
Strep/Tb infections
COCP / some Abx eg tetracycline / penicillin
Pregnancy
Malignancy
114
Area of skin depigmentation, usually in hot countries and associated with areas that get sweaty / covered by clothes? Casued by? Rx?
pityriasis versicolor
Malassezia globosa
Topical antifungal
115
What causes ring worm? rx?
Trichophyton Rubrum
Topical antifungal
116
Herald red patch -> multiple others with no other Sx and normal blood =?
Pityriasis rosea
[treatment conservative and usually just clears by 12 weeks]
[Rosea for red patch ]
117
Smooth circular patches of hair loss - may feel tingly?
Itchy scalp with patches of hair loss + scaling?
Alopecia acreta
Tinea capitis
118
What is male hair loss pattern called
Androgenetic alopecia
119
Drug Rx of alopecia acreta?
Topical steroids / minoxidil
120
What is the term for generalised hair loss over scalp and usually occurs a couple months after high stress / malnutrition / child birth?
Telegen effluvium
121
What white cell is raised in toxic epidermal necrolysis?
Eosinophils
122
Score system for severity of SJS/TEN
SCORETEN
123
Exclamation mark hairs
Alopecia areata
124
Areas of depigmented skin patches often with little patches of hair loss? Assoc with? Important blood test?
Rx?
Vitiligo
Autoimmune conditions
Thyroid function tests
Usually just conservative
-Can use topical steroids / phototherapy however often just persists
125
Lichen planus or lichen sclerosis in koebner phenomenon
P for P
Planus for phenomenon
126
Depigmented itchy skin lesions with increased peripheral nerve growth and raised inflam markers
Mycobacterium leprae
127
Itchy wheals (raised) lesions which keep coming up? Flare Rx? Long term? If that isn't working?
Hives (urticaria)
Antihistamines +/- steroids for flare
Longer-term antihistamines usually at least 2 with an increased dose and then can add in an LRA (montelukast)
->ciclosporin / tacrolimus
->Finanlly omalizumab if all else fails (mab at IgE)
128
Diagnosis of pseudoxanthoma (chicken skin)
Skin biopsy
129
Diagnose Marfan's
Fibrillin 1 gene testing
130
Bar psoriasis and nail fungal infections what systemic disease causes onycholysis
Thyrotoxicosis
131
Acanthosis nigrans is? associated with what ok and what bad thing?
Hyperpigmented velvety skin in skin folds
Insulin resistance
Gastric Ca
132
Area of erythema which then rapidly develops into multiple pus-filled papules? Assoc with?
PLEVA
EBV (this if uni student) with sore throat / atypical lympcytes on blood film
Toxoplasmosis
HIV
CMV
Staph/strep
[AKA there will be a clue in question for which one it is causing it]
133
Cancer + blistering rash = ? Antibodies associated?
Paraneoplastic pemphigus
anti-**plakin
134
First line Rx early syphilis
single IM Ben pen 2.4g
135
Eczema -> massive pustular eruption with yellow crusting (mostly in areas where eczema has prev been) =? Rx?
What if a localised reaction over eczema site?
Eczema herpeticum (herpes simplex / zoster)
Acyclovir
Staph -> fluclox
136
90% fungal nails caused by
Tricophyton rubrum
137
Pale atrophic plaques on vag =?
Rx?
If on penis tends to affect? Usually need?
Risk?
Lichen sclerosis
Topical steroids
Foreskin and glans (gets called balantis xerotica obliterans)
- circumsision
Small risk developing Squamous cell Ca
138
Differentiate lichen planus and sclerosis on a vag?
Both can itch
Slcerosis can be pale and atrophic (like a scar)
Planus - more Painful and coloured (Purple)
PPP
139
Fat - alcohol as trigger and rash in sun areas = ? Other trigger bar alcohol?
porphryia cutanea tarda
Oestrogen
140
Usual Rx in porphryia cutanea tarda
Avoid sun / alcohol.
Stop COCP
Plebotomy if ferrin >600
Can use hydroxychloroquine if less and prefer [mobilised porphyrins from liver -> excreted in urine]
Needs HIV / HepC rx
141
Diabetes, peripheral neuropathy. Large waxy yellow lesion on shin with ulceration
Necrobiosis lipoidica
142
Which lymphoma usually on skin (especially men aged 60)? What are the 2 types?
Cutaenous T-cell lymphoma
Mycosis fungoities and sezary syndrome
143
When are atypical lymphocytes with cerebriform nuclei seen?
Sezary syndrome (sezary cells)
144
Intensley itchy rash on flexural surface eg wrist. Koeberners phenomenom. Violet papules with white streaks ? IxRx?
Lichen planus (purple papules)
Usually no Ix and no Rx and will just get better
145
Red scaling rash in sun-exposed areas. Bald patches on the scalp. Scarring and pigmentation change =? Rx?
Discoid lupus
ANA = WILL BE NEGATIVE
Need sun protection
One of few indications for HIGH strength steroids for face
->Hydroxycloriquine / acretin
146
Diabetes with small erythermatous papules which coalesce into an area of erythema
Granuloma annulare
147
Which conditions are associated with pyoderma gangrenosum?
Necrotic ulcers are GRIMP
Granulomatous with polyangitis
Rhem A
IBD
Myeloproliferative disorders / lymphoma
PBC
148
Differentiate pyoderma gangrenosum and erythema nodosum
Pyoderma - deep ulcerating necrotic ulcers. Demonstrate cribriform pattern of scarring
Erythema - Painful erythematous lumps
-Eg TB, sarcoid, strep, IBD
149
Talk about pemphigus differences to pemphigoid
Pemphigus - oral lesions common,
Blisters may have all been scratched away as superficial and fragile.
Antidesmoglein antibodies
150
First line Ix contact dermatitis? What type of hypersensitivity reaction is contact dermaitits
Patch testing
Type IV
151
Whats most important Ix for Dx of NF1
Slit lamp of eye
Otherwise physical exam and FHx
152
Australian. Painless lesion on penis which then turns into a heaped-up ulcer? The biopsy will show? Rx?
Granuloma inguinale
Donovan bodies
Doxy / co-trimoxazole
153
Sore genital ulcers with ragged edges and painful swollen inguinal lymph nodes? Caused by which bug
Chancroid
Haemophilus ducreyi
154
Which antihypertensive worsens psoriasis? Other drugs?
b blockers
Lithium
Antimalrials
155
Diagnosis of leprosy? Stab at recognising Rx?
Skin biopsy
->Zheil neilson / Fite staining
Dapsone, rifampacin and clofazimine
156
Strong family history. Warty lesions on chest / back / scalp. Nail dystrophy ? Rx if needed?
Dariers disease
acitretin if needed
157
Presents as pemphigus but the mucosa are unaffected and blisters all crusted
Pemphigus foliaceus
158
Bar Vit D3 (niacin) which other deficiency leads to dermatitis but without as predominant depression/dementia symptoms and more effects on nails.
Zinc
159
T1DM. Symmetrical areas of hypopigmentation = ?
What if there was a textural change and asymetrical?
Vitiligo
Morphoea (may be hypo or hyper pigmented)
160
Which drugs are known to trigger pemphigoid
Furosemide
ACEi
NSAIDS
Penicillamine
161
post EBV now have a papular rash covering chest / Abdo. Rx?
Topical tacrolimus
[Ideally don't use steroids over a large area in young people]
162
Pemphigus biopsy
IgG / Complement deposits / antidesmoglein 1 and 3
163
differentiate pemphigus Vulgaris and pemphigus follicularis on antibodies
Vulgaris - desmoglein 1 and 3
Follicularis - Desmoglein 2
164
What is henna tattoo which causes allergic reaction
PPD
165
Necrobiosis lipoidica Rx
Very poorly responsive to treatment - non-proven to work as it is due to small vessel damage and necrosis of dermal collagen
166
What is positive nickolsky sign in SJS
Pressure on skin causes blistering within hours
167
Acne flow chart Rx
Topical eg Benzyl perioxide then topical retinoid
Topical abx
Oral Abx x 2
Oral retiniod
168
Dermatitis, dementia and diarrhoea =? If other extra symptoms eg raised aLT what might have caused it?
Vit B3 - Niacin
[There B3 D's in this condition]
Carcinoid syndrome - tryptophan used to make serotonin and non left for conversion to Vit B3
169
Which rash do 1/3 of people with new Ca present with
Dermatomyositis
170
Lifestyle Rx of rosacea
Stopping drinking
171
Acute intermittent porphyria
Inheritance of what?
Presentation?
Key biochem fidning?
Dominant inheritance of deficiency in porphrobilinogen
Neuropsychiatric / GI disturbance. Dark red urine (porphyrins)
Often SIADH
172
Acute intermittent porphyria
Rx?
Prevention of cyclic attacks?
Dextrose oral / IV
IV haemin
Haem arginate
Can use GnRH analogues eg goserelin in women
173
Acute intermittent porphyria monitoring? risk?
yearly uroporphyrins and LFTs
Liver US when >50 as risk of HCC
174
Mucocutaneous leishmaniasis Rx
Sodium Stibogluconate
175
2 main causes of angioedema in absence of urticaria
ACEi
C1esterase deficiency
176
Rx hand eczema which is resistant to oral steroids and super potent topical steroids
Alitrenitoin
[Or ciclosporin if CI'd]
177
Herald patch -> Christmas tree pattern of salmon pink rash
Pityriasis roseacea
178
Which drug causes onchyolysis?
Tetracyclines Eg doxy
179
eczema with erythema and pustule formation + yellow crusting Rx ? When would you suspect viral?
Topical Abx and continued topical corticosteroids
If herpeticum it would mention vesicles, not pustules
[So long as systemically well]
180
Fat man with erythematous plaque and scaling border on inner thigh Dx?Ix? Rx?
Tinea Cruris
Skin scrapings
Topical antifungals
181
When is the ink test used?
Scabies - ink onto hands then wipped off and it stays in the burrows
182
Paraneoplastic pemphigus usually which Ca?
Non-hodgkins lymphoma
183
Symmetrical maculopapular rash on trunk and limbs which is pale pink and not itchy. Mucosal erosions. Generalised muscle and joint pains/lymphadenopathy? What are the plaques which form in the flexures called?
Secondary syphilis
Condylomata lata
183
Symmetrical maculopapular rash on trunk and limbs which is pale pink and not itchy. Mucosal erosions. Generalised muscle and joint pains/lymphadenopathy? What are the plaques which form in the flexures called?
Secondary syphilis
Condylomata lata
184
Drugs causing photosensitivity
QR STAND
Q- Quinine, Quinolones, Quinidine
R- Retinoids
S- Sulphonamides, Sulfonylureas
T- Tetracyclines, Thiazides
A- Amiodarone
N- NSAID'S-- Ibuprofen, naproxen, celecoxib
D- Dapsone
185
When is a lesion melanoma until proven otherwise
Asymmetry
Border is irregular
Colour varies throughout
Diameter >6mm
Evolving / growing
186
Most effective intervention for molluscum contagiousosum
Cryotherapy
187
tender red nodules on shins in pregnant
eRYTHEMA NODOSUM
188
Peri-stomal pyoderma Rx
Topical tacrolimus
189
Velvity dark patch on lip and in neck folds? Key associations
Acanthosis nigrans
Cushings, acromegally or other insulin resistant
Gastric adenocarcinoma , Endometrial Ca
