derm Flashcards

1
Q

NICE criteria for dx atopic dermatitis

A

Itchy skin + 3/5 of
- visible flexural eczema (eryhtematous, itchy, poorly demarcated rash) face, or scalp - cheeks/ extensors if <18m
- Hx of felxural eczema
- Hx dry skin
- Hx atopy (in dividual/ 1st degree relative if <4yo)
- onset <2yo (dont use in <18m)

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2
Q

3 complicaitions of eczema

A

Eczema herpeticum - emergency, HSV inffection 2o to atopic dermatitis
superficial bacterial infection (stap/strep)
erythroderma (emergency) - widespread erythema >90% skin surface Leads to: heat and fluid loss –> hypothermia and systemic Sx

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3
Q

what type of hypersensitivity is atopic dermatits

A

Typ1 hypersensitivity - IgE mediated

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4
Q

give stepwise topic mx in eczema

A
  1. emmolient (Aveeno, E45, Diprobase)
  2. Steroids -
    - mild: hydrocortisone, Mod: eumovate, Potent betnovate, V. potent: Dermovate
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5
Q

how do the following subtypes of psoriasis present
- plaque psoriasis
- flexural
-guttate
- pustular

A

plaque - most common, well-demarcated red, scaly patches on extensor surfaces, sacrum, scalp

flexural - smooth patches on skin
(affects skinfolds (armpits, under breasts, genital areas - smooth, shiny scaling)

guttate - strep infection triggered rash, multiple red, teardrop leasions

pustular - palms & soles

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6
Q

2 non-skin features of psoriasis

A

nails: pitting, onycholysis (separation of the nail from the nail bed)
subungual hyperkeratosis, loss of the nail

arthritis

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7
Q

molluscum contangiosum advice

A

self-limiting (12-18m)

but contagious, so dont share towels etc

school exclusion not required

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8
Q

what is the difference in presentation between lichen planus and lichen sclerosus

A

Lichen
planus: purple, pruritic, papular, polygonal rash on flexor surfaces. Wickham’s striae over surface. Oral involvement common

sclerosus: itchy white spots typically seen on the vulva of elderly women

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9
Q

Mx options for actinic keratosis ( give 3)

A

prevention of further risk: e.g. sun avoidance, sun cream
fluorouracil cream: typically a 2 to 3 week course. The skin will become red and inflamed - sometimes topical hydrocortisone is given following fluorouracil to help settle the inflammation
topical diclofenac: may be used for mild AKs. Moderate efficacy but much fewer side-effects

remeber actinic keratosis on sun exposed areas of the body

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10
Q

x2 differences in appearance between Plaque psoriasis and eczema

A

found in similar areas but

plaque posriasis:
- well defined borders
- silvery scale

Eczema
- poorly defined borders
- no silvery scale

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11
Q

give 2 main causes of impetigo

A

strep pyogenes & staph aureus** most common

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12
Q

1st line mx in impetigo if

  • systemically well
  • extensive disease (systemically unwell)
A

well: Hydrogen peroxide 1% cream (antiseptic) (Fusidic acid 2% - antibiotic, 2nd line)

unwell: oral fluclox (erythromycin 2nd line)

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13
Q

what bacteria is a golden crust associated with

A

staph aureus

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13
Q

should children be kept off school if they have impetigo?

A

yes - contagious

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14
Q

describe
- mild
-mod
-sev acne

A

mild - open & closed comedones, may have sparse inflammatory lesions

mod - widespread non-inflammatory lesions & neumerous papules & pustules

sev - extensive inflammatory lesions, with nodules/pitting/scarring

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15
Q

give the stepwise max for acne (5)

A

single topical therapy - topical retinoids/benzoyl peroxide)

topical combination therapy ( topical antibiotic, benzoyl peroxide, topical retinoid

  1. oral Abx (tetracyclines - lymecycline, doxycycline erythmomycin in pregnancy ) - max use 3 months
    co-prescribe topical retinoid/benzoyl peroxide
  2. COCP in women (diannette aka co-cyrindiol)
  3. oral isotretinoin ( specialist)
16
Q

x eczema complication

bacterial infection of eczema

eczema herpeticum

A

bacterial - oral Abx (e.fg. fluclox)/ admit if severe

eczema herpeticum - oral aciclovir ( IV if severe)

17
Q

stepwise mx in eczema

maintenance

flares

A

maintenance
- avoid irritation
- emollients (thin creams e.g. E45, Diprobase cream, aveeno cream, cetraben cream) (thick, greasy e.g. hydromol ointment, diprobase ointment, cetraben ointment)

flares
steroid
steroid ladder
Mild - hydrocortisone (0.5-2.5%)
Mod - Eumovate
Potent - Betnovate
V. potent Dermovate

18
Q

features of a BCC (x4)

A

most common type - nodular

  • sun-exposed sites (head and neck)
  • initially a pearly, flesh-coloured papule
  • telangiectasia
  • may later ulcerate - leaving a dcentral ‘crater’
19
Q

what cream can be used in actinic keratosis management which may cause redness and inflammation of skin

A

fluorouracil cream: 2 -3 week course.

topical hydrocortisone is given following fluorouracil to help settle the inflammation

20
Q

define bowens disease

A

precancerous dermatosis - precursor to SCC (5-10% chance of becoming SCC)

21
Q

describe the features of Bowens disease (x4)

A

red, scaly patches
10-15 mm
slow-growing
sun-exposed areas

22
Q

Mx for bowens disease

A

topical 5-fluorouracil cream (BD, 4wks)

causes significant inflammation/erythema - so give Topical steroids (hydrocortisone) - like actinic keratoses Mx, but this is 2-3 wks

23
Q

what are the 4 main types of melanoma

A

superficial spreading (70% - arms, legs, backs, chest , yougn people) - mole w/ diagnostic features

nodular 2nd commonest (sun exposed skin, middle aged - red/black bleeding/oozing lump)

lentigo maligna less common - chronically sun-exposed skin, older people - mole w/ diagnostic features

acral lentiginous - rare
(Nails, palms, soles - in darker skinned people) - subungual pigmentation (Hutchinsons sign) or on palms/feet

24
apart from webs of the hands, where else does scabies present
axillae,, extensor surfaces, upper back, lower trunk, genitals, peri-anal presents - inear burrows on the side of fingers, interdigital webs and flexor aspects of the wrist in infants, the face and scalp may also be affected secondary features are seen due to scratching: excoriation, infection
25
what pt group gets crusted scabies
hyperinfestation in immunocompromised Presents: Extremely thick, hiyerkeratotic, scaly, fissured skin * Inflammation with >1million mites (normally 10-20) * High eosinophil count, IgE and IgG * High risk of 2ᴼ infection and sepsis (partly due to underlying immune suppression)
26
1st & 2nd line Mx in scabies
permethrin 5% is first-line malathion 0.5% is second-line treat whole household at the same time
27
instructions for applying permethrin & malathion
creams for scabies apply to skin allow to dry and leave on the skin for 8-12 hers (permethrin), or for 24hrs (malathion) wash off reapply if insecticide is removed during the treatment period, e.g. If wash hands, change nappy, etc repeat treatment 7 days later ( day 1 and day 8)
28
tx in norwegian scabies
norwegian = crusted oral Ivermectin & isolation
29
what type of hyperwsensitivty reaction causes contact dermatitis
Type VI Type IV hypersensitivity reactions are also known as delayed-type hypersensitivity as the reaction occurs 48-72 hours after exposure to an antigen. They are T-cell mediated and do not involve antibodies
30
what type of Gell and Coombs hypersensitivity raction causes anaphylaxis
Type I - IgE mediated
31
which of the sx of rosacea typically presents initilally
flushing is often first symptom typically affects nose, cheeks and forehead telangiectasia are common later develops into persistent erythema with papules and pustules rhinophyma ocular involvement: blepharitis sunlight may exacerbate symptoms
32
what ophtho condition is associated with rosacea
blepharitis
33