DERM - Benign skin tumors Flashcards Preview

Year 2 Specialty Medicine > DERM - Benign skin tumors > Flashcards

Flashcards in DERM - Benign skin tumors Deck (24):
1

what is leser trelat sign? what does it mean?

- sudden onset of numerous SKs
- may indicate an underlying visceral malignancy

2

what is the morphology of an acrochordon (skin tag)?

fibrovascular core covered by benign squamous epithelium

3

cyst with a punctum?

epidermoid cyst

4

presentation: single subcutaneous nodule at birth on lateral aspect of upper eyelid

dermoid cyst

5

what is the cause of cowdens disease?

AD mutation of PTEN

6

what is the presentation for cowdens disease?

- oral lesions
- acral keratoses
- macrocephaly
- trichilemmoma**** (diagnostic)

7

cowdens disease carries a risk of cancer in what organs?

- breast
- thyroid

8

ghost cells are characteristic of _____________--

pilomatrixoma

9

fibrofolliculomas, trichodiscomas, acrochordons - diagnosis?

birt-hogg-dube syndrome

10

what is important to know about nevus sebaceous?

they are benign, but secondary tumors can arise within

11

yellowish dome shaped papules with central punctum?

sebaceous hyperplasia

12

what skin condition is seen in muir-torre syndrome?

sebaceous adenoma

13

muir torre syndrome is related to what cancer syndrome?

HNPCC

14

what is the inherited defect in muir torre syndrome? what is the inheritance?

- defect in DNA mismatch repair gene
- AD

15

what are the cutaneous findings in muir torre? visceral?

- cutaneous: sebaceous tumors (adenomas, sebaceoma, carcinoma, keratoacanthoma)
- visceral: GI, bladder, endometrium, breast

16

what is a cylindroma?

- pink red nodule on head and neck
- F:M 9:1

bubble gum bubble appearance

17

jigsaw puzzle histology?

cylindroma

18

- yellow / brown / orange papule or nodule
- solitary lesion on head / neck
- associated rarely with CML

xanthogranuloma (juvenile xanthogranuloma)

19

what is the significance of langerhans cell histiocytosis?

can involve internal organs

20

what is the IF for LCH?

CD1a

21

what is the EM finding on LCH?

birbeck granules

22

what is mortons neuroma?

non-palpable lesion that causes severe pain in sole of foot

23

mucosal neuromas stain positive for ______

S-100

24

what is pathognomonic for NF1?

plexiform neurofibroma