Flashcards in derm terms Deck (62)
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1
loss of cohesion b/w keratinocytes caused by the breakdown of intercellular bridges
Acantholysis
2
thickening of the spinous cell layer (stratum spinosum) of the epidermis
Acanthosis
3
distal part of the extremities
Acral
4
hair loss
Alopecia
5
phase of hair cycle in which hair synthesis takes place
Anagen
6
lack of cellular differentiation and organization, a feature of neoplastic cells
Anaplasia
7
vascular reaction involving the deep dermis or subcutis and consisting of edema manifested as giant wheal; caused by dilation and increased permeability of capillaries (deeper version of urticaria)
Angioedema
8
programmed cell death
Apoptosis
9
reduction in size of a cell, tissue, organ, or part
Atrophy
10
marked intracellular fluid accumulation in the cells of the epidermis
Ballooning Degeneration
11
localized collection of fluid usually in or beneath the epidermis
Blister
(vesicle or bulla)
12
large blister (>1.0 cm)
Bulla
13
a malignant neoplasm of epithelial origin that has not invaded thru the basement membrane
carcinoma in situ
14
the stage of the hair cycle where old hairs are shed
Exogen
15
fluid, cells, or debris from blood vessels deposited in or on other tissues
Exudate
16
cleft or groove
Fissure
17
inflammation of a hair follicle
Folliculitis
18
circumscribed, painful, nodule (accumulation of pus) in the dermis secondary to follicular rupture
Furuncle
19
rupture of follicles usually caused by inflammation, distention, and/or trauma leading to entry of follicular contents into the dermis
Furunculosis
20
a genetically determined disorder of the skin
Genodermatosis
21
smooth skin, hairless skin
Glabrous
22
localized, tumor-like malformation of mature cells and tissues that includes normal components of the organ in which the ______ arises but that is disorganized, present in excess, & sometimes larger than normal.
usually, one tissue element predominates.
not a true neoplasm b/c it involves the proliferation of more than one cell type & often includes the development of complex structures such as arteries or follicles
Hamartoma
(Follicular Hamartoma, Vascular Hamartoma)
23
intracellular fluid accumulation in cells of the basal epidermis
Hydropic degeneration
24
histologic term for thickening of stratum corneum
Hyperkeratosis
25
increase in the number of normal cells
Hyperplasia
26
incomplete development
Hypoplasia
27
less hair than normal
Hypotrichosis
28
congenital skin disorder in which the skin is thickened by scales (hyperkeratosis) that can crack into plates resembling fish scales
Ichthyosis
29
bacterial dermatitis characterized by pustules
Impetigo
30
slow growing, a term applied to persistent ulcers on the lips of cats
sometimes incorrectly called "rodent ulcer" a term from the human literature used to refer to ulcerated basal cell carcinoma
Indolent
31
shedding of layers or scales
Exfoliation
32
non-inflammatory lesion of the skin
Dermatosis
33
dandruff
Detritus
34
abnormal, premature, or imperfect keratinization
Dyskeratosis
35
abnormal development; term may be used in association with a congenital or inherited developmental anomaly or in association w/an abnormality in maturation of cells within a tissue
Dysplasia
36
shedding of hair
Effluvium
37
degeneration of dermal connective tissue leading to accumulation of elastic fibers; sometimes seen with solar dermatitis
Elastosis
38
peripheral expanding ring of scale
Epidermal Collarette
39
inflammation of the epidermis
Epidermitis
40
separation of the epidermis from the dermis
Epidermolysis
41
having a predilection to enter the epidermis or other epithelial structures as seen w/cutaneous T cell lymphoma (mycosis fungicides)
Epidermotropic/Epitheliotropic
42
loss of all or part of the thickness of the epidermis
Erosion
43
rapid development of skin lesion associated with redness
Eruption
44
redness of skin caused by congestion of capillaries
Erythema
45
an intense focal folliculitis usually caused by a dermatophyte infection
Kerion
46
intraepidermal dendritic Ag-presenting cells
Langerhans' cells
47
superficial loss of epidermal layers caused by physical trauma (scratching)
Excoriation
48
infection of the stratum corneum of the epidermis, hair, or claws w/fungi of the genera Microsporum, Epidermophyton, or Trichophyton
Dermatophytosis
49
transition phase of the hair cycle b/w growth and resting phases
Catagen
50
an acute bacterial infection of the dermis and subcutis that spreads to surrounding soft tissues and is characterized by erythema, warmth infection is most often a penetrating wound in the area of infection; can also cause fever and enlarged lymph nodes
Cellulitis
51
plug of follicular stratum corneum and dried sebum in a hair follicle that leads to follicular distention
Comedo (pl. Comedones)
52
production of stratum corneum by terminal epidermal differentiation
Cornification
53
material formed by drying of exudate or secretion on the skin surface
Crust
54
naturally pigmented black or brown mycelium or conidium
Dermatiaceous
55
small molecular we. protein molecule (generally <30kD) that are mediators of inflammation and growth
Cytokines
56
inflammation of the skin
Dermatitis
57
hardening of the skin as a result of inflammation or fibrosis
Indurated
58
inflammation arranged in a layer close to and often obscuring the epidermal-dermal junction (interface), and w/vacuolated (hydropic degeneration) and sometimes apoptopic basal cells; the inflammation can be mild (cell poor) or extensive (cell rich)
Interface
59
dermatitis that develops b/c of friction b/w opposing skin surfaces (e.g. adjacent folds)
Intertrigo
60
the epidermal cells that synthesize keratin and comprise more than 90% of epidermal cells
Keratinocytes
61
an uncommon to rare circumscribed papular, plaque-like, or linear focus of proliferative keratinocytes covered by thick stratum corneum; can be caused by sun exposure (solar or actinic) or can be idiopathic (lichenoid, linear, cannon)
Keratosis
(pl. Keratoses)
62
