derm terms

Question 1

loss of cohesion b/w keratinocytes caused by the breakdown of intercellular bridges

Answer 1

Acantholysis

Question 2

thickening of the spinous cell layer (stratum spinosum) of the epidermis

Answer 2

Acanthosis

Question 3

distal part of the extremities

Answer 3

Acral

Question 4

hair loss

Answer 4

Alopecia

Question 5

phase of hair cycle in which hair synthesis takes place

Answer 5

Anagen

Question 6

lack of cellular differentiation and organization, a feature of neoplastic cells

Answer 6

Anaplasia

Question 7

vascular reaction involving the deep dermis or subcutis and consisting of edema manifested as giant wheal; caused by dilation and increased permeability of capillaries (deeper version of urticaria)

Answer 7

Angioedema

Question 8

programmed cell death

Answer 8

Apoptosis

Question 9

reduction in size of a cell, tissue, organ, or part

Answer 9

Atrophy

Question 10

marked intracellular fluid accumulation in the cells of the epidermis

Answer 10

Ballooning Degeneration

Question 11

localized collection of fluid usually in or beneath the epidermis

Answer 11

Blister

vesicle or bulla

Question 12

large blister (>1.0 cm)

Answer 12

Bulla

Question 13

a malignant neoplasm of epithelial origin that has not invaded thru the basement membrane

Answer 13

carcinoma in situ

Question 14

the stage of the hair cycle where old hairs are shed

Answer 14

Exogen

Question 15

fluid, cells, or debris from blood vessels deposited in or on other tissues

Answer 15

Exudate

Question 16

cleft or groove

Answer 16

Fissure

Question 17

inflammation of a hair follicle

Answer 17

Folliculitis

Question 18

circumscribed, painful, nodule (accumulation of pus) in the dermis secondary to follicular rupture

Answer 18

Furuncle

Question 19

rupture of follicles usually caused by inflammation, distention, and/or trauma leading to entry of follicular contents into the dermis

Answer 19

Furunculosis

Question 20

a genetically determined disorder of the skin

Answer 20

Genodermatosis

Question 21

smooth skin, hairless skin

Answer 21

Glabrous

Question 22

localized, tumor-like malformation of mature cells and tissues that includes normal components of the organ in which the ______ arises but that is disorganized, present in excess, & sometimes larger than normal.
usually, one tissue element predominates.
not a true neoplasm b/c it involves the proliferation of more than one cell type & often includes the development of complex structures such as arteries or follicles

Answer 22

Hamartoma

Follicular Hamartoma, Vascular Hamartoma

Question 23

intracellular fluid accumulation in cells of the basal epidermis

Answer 23

Hydropic degeneration

Question 24

histologic term for thickening of stratum corneum

Answer 24

Hyperkeratosis

Question 25

increase in the number of normal cells

Answer 25

Hyperplasia

Question 26

incomplete development

Answer 26

Hypoplasia

Question 27

less hair than normal

Answer 27

Hypotrichosis

Question 28

congenital skin disorder in which the skin is thickened by scales (hyperkeratosis) that can crack into plates resembling fish scales

Answer 28

Ichthyosis

Question 29

bacterial dermatitis characterized by pustules

Answer 29

Impetigo

Question 30

slow growing, a term applied to persistent ulcers on the lips of cats sometimes incorrectly called "rodent ulcer" a term from the human literature used to refer to ulcerated basal cell carcinoma

Answer 30

Indolent

Question 31

shedding of layers or scales

Answer 31

Exfoliation

Question 32

non-inflammatory lesion of the skin

Answer 32

Dermatosis

Question 33

dandruff

Answer 33

Detritus

Question 34

abnormal, premature, or imperfect keratinization

Answer 34

Dyskeratosis

Question 35

abnormal development; term may be used in association with a congenital or inherited developmental anomaly or in association w/an abnormality in maturation of cells within a tissue

Answer 35

Dysplasia

Question 36

shedding of hair

Answer 36

Effluvium

Question 37

degeneration of dermal connective tissue leading to accumulation of elastic fibers; sometimes seen with solar dermatitis

Answer 37

Elastosis

Question 38

peripheral expanding ring of scale

Answer 38

Epidermal Collarette

Question 39

inflammation of the epidermis

Answer 39

Epidermitis

Question 40

separation of the epidermis from the dermis

Answer 40

Epidermolysis

Question 41

having a predilection to enter the epidermis or other epithelial structures as seen w/cutaneous T cell lymphoma (mycosis fungicides)

Answer 41

Epidermotropic/Epitheliotropic

Question 42

loss of all or part of the thickness of the epidermis

Answer 42

Erosion

Question 43

rapid development of skin lesion associated with redness

Answer 43

Eruption

Question 44

redness of skin caused by congestion of capillaries

Answer 44

Erythema

Question 45

an intense focal folliculitis usually caused by a dermatophyte infection

Answer 45

Kerion

Question 46

intraepidermal dendritic Ag-presenting cells

Answer 46

Langerhans' cells

Question 47

superficial loss of epidermal layers caused by physical trauma (scratching)

Answer 47

Excoriation

Question 48

infection of the stratum corneum of the epidermis, hair, or claws w/fungi of the genera Microsporum, Epidermophyton, or Trichophyton

Answer 48

Dermatophytosis

Question 49

transition phase of the hair cycle b/w growth and resting phases

Answer 49

Catagen

Question 50

an acute bacterial infection of the dermis and subcutis that spreads to surrounding soft tissues and is characterized by erythema, warmth infection is most often a penetrating wound in the area of infection; can also cause fever and enlarged lymph nodes

Answer 50

Cellulitis

Question 51

plug of follicular stratum corneum and dried sebum in a hair follicle that leads to follicular distention

Answer 51

Comedo (pl. Comedones)

Question 52

production of stratum corneum by terminal epidermal differentiation

Answer 52

Cornification

Question 53

material formed by drying of exudate or secretion on the skin surface

Answer 53

Crust

Question 54

naturally pigmented black or brown mycelium or conidium

Answer 54

Dermatiaceous

Question 55

small molecular we. protein molecule (generally <30kD) that are mediators of inflammation and growth

Answer 55

Cytokines

Question 56

inflammation of the skin

Answer 56

Dermatitis

Question 57

hardening of the skin as a result of inflammation or fibrosis

Answer 57

Indurated

Question 58

inflammation arranged in a layer close to and often obscuring the epidermal-dermal junction (interface), and w/vacuolated (hydropic degeneration) and sometimes apoptopic basal cells; the inflammation can be mild (cell poor) or extensive (cell rich)

Answer 58

Interface

Question 59

dermatitis that develops b/c of friction b/w opposing skin surfaces (e.g. adjacent folds)

Answer 59

Intertrigo

Question 60

the epidermal cells that synthesize keratin and comprise more than 90% of epidermal cells

Answer 60

Keratinocytes

Question 61

an uncommon to rare circumscribed papular, plaque-like, or linear focus of proliferative keratinocytes covered by thick stratum corneum; can be caused by sun exposure (solar or actinic) or can be idiopathic (lichenoid, linear, cannon)

Answer 61

Keratosis | pl. Keratoses

Question 62

thickening of the skin w/accentuation of skin creases marked by marked acanthosis

Answer 62

Lichenification