Dermatology

Question 1

Which bacteria causes nail infections?

Answer 1

Pseudomonas

Question 2

Yellow nail syndrome triad

Answer 2

Nail changes, lymphoedema, resp (pleural eff, bronchitis)

Question 3

Yellow nail syndrome associations

Answer 3

RA, malignancy, immunodeficiency

Question 4

Yellow nail syndrome Rx

Answer 4

Vit E, zinc, itraconazole

Question 5

Granuloma annulare associations

Answer 5

T2DM, thyroid disease, lymphoma, HIV

Question 6

Granuloma annulare mechanism

Answer 6

Delayed hypersensitivity for components of dermis, driven by TNFalpha

Question 7

Proportion of sarcoidosis that get skin involvement

Answer 7

1/3

Question 8

Derm manifestations of sarcoidosis

Answer 8

Plaque, mac-pap eruptions, erythema nodosum, erythema multiforme

Question 9

Local Rx sarcoid skin disease

Answer 9

Topical steroids

If severe - MTX

Question 10

Most common presentation of cutaneous T-cell lymphoma

Answer 10

Mycosis fungoides

Question 11

Management options cutaneous T-cell lymphoma

Answer 11

Avoid antigen, UVB, MTX, extracorporeal photopheresis

Question 12

3 causes of Sweet’s

Answer 12

AML, pregnancy, RA, IBD, drugs

Question 13

Rx of Sweet’s

Answer 13

Withdraw cause, steroids

Question 14

Where does pyoderma occur

Answer 14

At site of minor trauma

Question 15

Key complication of pyoderma

Answer 15

Deep fungal infection e.g. scedosporidium

Question 16

Vitiligo - when repigmentation occurs, where does it occur?

Answer 16

Follicles

Question 17

What is Koebner’s phenomenon?

Answer 17

Vitiligo worse at sites of scars

Question 18

Rx vitiligo

Answer 18

Steroids, CNIs, UVB

Question 19

Erythema multiforme description

Answer 19

Bilateral fixed papules +/- target lesions

Question 20

Triggers for erythema multiforme

Answer 20

Mycoplasma, EBV, CMV, HSV, HIV, hepatitis

Question 21

DIfference between major and minor erythema multiforme

Answer 21

Mucosal involvement

Question 22

Cut-off SJS vs TEN

Answer 22

TEN >10% epidermal detachment, SJS <10%

Question 23

Nikolsky sign SJS/TEN

Answer 23

Epidermal detachment with gentle pressure

Question 24

Main part of body affected SJS/TEN

Answer 24

Trunk

Question 25

Key specific Rx SJS/TEN beyond supportive

Answer 25

IVIg 1g/kg/d for 3/7

Question 26

What UV are we mostly exposed to?

Answer 26

UVA 95%

Question 27

Which UV penetrates deeply

Answer 27

UVA

Question 28

Which UV is sunscreen based upon

Answer 28

UVB

Question 29

Actinic keratoses are precursors to:

Answer 29

SCC

Question 30

Which haem malignancy gets very aggressive SCC

Answer 30

CLL

Question 31

Describe dermatitis herpetiformis

Answer 31

Itchy vesicular lesions found on extensor surfaces, back, scalp

Question 32

Dermatitis herpetiformis assocxiation

Answer 32

Coeliac

Question 33

Porphyria cutanea tarda is due to deficiency in:

Answer 33

UROD

Question 34

Porphyria cutanea tarda associations

Answer 34

Alcohol excess Hep B/C Iron overload

Question 35

Diagnosis of porphyria cutanea tarda

Answer 35

Elevated urine or plasma porphyrins

Question 36

Erythema nodosum causes

Answer 36

Sarcoid, IBD, OCP, pregnancy, cancer, infection

Question 37

Which infection is EN associated with?

Answer 37

Strep pharyngitis

Question 38

Treatment of erythema nodosum

Answer 38

NSAIDs

Question 39

Bullous pemphigoid description

Answer 39

Tense subepidermal blisters