Development and Organisation of the Alimentary System, Liver & Pancreas Flashcards

(49 cards)

1
Q

Accessory Organs of the gut

A
  • salivary glands
  • liver & gall bladders
  • pancreas
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2
Q

Where do mouth parts develop from?

A

branchial arches

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3
Q

Where (other than the mouth) forms from the branchial arches?

A
  • ear
  • hand
  • neck
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4
Q

Describe mesoderm

A
  • middle developmental layer between the ectoderm and endoderm
  • gives rise to the skeleton, muscle, heart and bones
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5
Q

What are indents in the branchial arches known as?

A

pharyngeal clefts or grooves

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6
Q

What are supplied by a cranial nerve in branchial arches?

A

cartilage and muscular components

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7
Q

How many pharyngeal arches are there in branchial arches?

A

6

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8
Q

How many clefts are there in branchial arches?

A

4

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9
Q

What develops from the first branchial arch?

A
  1. skin of jaw
  2. salivary glands
  3. tooth enamel
  4. buccal cavity
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10
Q

What develops from the 1st cleft of branchial arches?

A
  • external components of middle ear
  • tympanum
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11
Q

What develops from the 1st pouch of branchial arches?

A

auditory tube

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12
Q

What develops from the 2nd, 3rd and 4th branchial arches?

A

skin of the ear & neck

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13
Q

What develops from the 2nd pouch of branchial arches?

A

tonsils & lymphatics

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14
Q

What develops from the 3rd pouch of branchial arches?

A

thymus & thyroid

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15
Q

What develops from the 4th pouch of branchial arches?

A

thyroid

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16
Q

What 3 “parts” are in each branchial arches?

A
  1. nerves
  2. arteries
  3. cartilage
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17
Q

What does the gut develop as?

A

an endodermal tube

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18
Q

What surrounds the endoderm?

A

Splanchnic mesoderm

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19
Q

What forms muscle & connective tissue?

A

Splanchnic mesoderm

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20
Q

What provides nutrients to the embryo as the placental plate develops?

21
Q

At what week of embryo development do accessory organs appear?

22
Q

What are the 4 layers of the gut wall?

A
  1. mucosa
  2. submucosa
  3. muscularis externa
  4. serosa
23
Q

Describe mucosa

A
  • lines the gut lumen
  • has 3 layers
  • has a thin ring of longitudinal smooth muscle
  • contains mucus and electrolyte-secreting glands
    -surface normally highly folded to increase digestive surface area
24
Q

Describe submucosa

A
  • thick layer of connective tissue
  • provides structural support and elasticity
  • contains submucosal nerve network
25
Describe muscularis externa
- has inner ring of circular smooth muscle - has outer ring of longitudinal muscle - contracts tube diameter - constricts gut length
26
Describe serosa
- outer connective tissue layer - secretes fluid to lubricate organs of the coelom - attached to mesenteric membranes
27
What is the primary region of nutrient absorption?
the small intestine
28
What increases the absorptive area in the small intestine?
circular folds, villi, and microvilli
29
What are villus lined with?
epithelial cells and mucus-secreting cells
30
What is contained within villus?
- an arterial and venous circulation - a lymphatic vessel
31
What is the lymphatic system prominent in?
lipid absorption
32
Describe the crypt of lieberkuhn
- site of enterocyte - a site of water and mucus secretion
33
What is the primary function of the large intestine
water re-absorption and drying of feces
34
Where does the liver develop from?
ventral hepatic bud from foregut endoderm
35
What is the liver organized into?
units called lobules
36
What is each lobule in the liver fed by a branch of?
the hepatic artery and the portal vein
37
Where is bile stored?
the gall bladder
38
What is a sinusoid?
blood from the hepatic artery and portal vein that flows into the same capillary vasculature
39
Where does the alimentary tube develop from?
the cephalic and caudal parts of the embryo
40
Where does the pancreas develop from?
dorsal & ventral pancreatic buds
41
What is the pancreas organized into?
exocrine and endocrine structures
42
How is the exocrine pancreas organized?
as a series of glands along the pancreatic duct which drains into the duodenum
43
Describe duct cells in the exocrine pancreas
- exist at the base of each gland - secrete bicarbonate - the bicarbonate neutralizes digestive juices from the stomach
44
Describe acinar cells in the exocrine pancreas
- at the head of each gland - secrete digestive enzymes into the duct
45
Where does the exocrine pancreas develop from?
the ventral pancreatic bud
46
Where does the endocrine pancreas develop from?
the dorsal pancreatic bud
47
What are islets of Langerhans in the endocrine pancreas?
a series of secretory islets perfused by a capillary network
48
What do islet cells do?
secrete metabolic hormones (insulin, glucagon and somatostatin)
49