Diagnostics: introduction and chemical pathology lab Flashcards Preview

MCD Y2: Laboratory diagnostic methods > Diagnostics: introduction and chemical pathology lab > Flashcards

Flashcards in Diagnostics: introduction and chemical pathology lab Deck (20):
1

Recall 4 cardiac enzymes that may be measured in the lab to assess cardiac damage

Troponins
Creatine kinase
Aspartate aminotransferase
Lactate dehydrogenase

2

Why are cardiac enzymes a good measure of cardiac damage?

They are released when heart tissue is damaged

3

What colour top is on the U&Es blood test bottle?

Red/ yellow

4

What is measured in a U&E test?

Na+
K+
Urea
Creatinine

5

Why are U&Es useful for assessing kidney function?

Urea = breakdown product of protein
Creatinine = constantly produced by muscles
Both excreted by kidneys

6

What is urea a good marker of, in addition to kidney function?

Extent of dehydration

7

Why is urea a good marker of dehydration?

dehydration --> renal water resorption --> urea coincidentally reabsorbed

8

What happens to urea and creatinine levels in renal disease?

Both rise

9

Describe the movement of creatinine in the kidney

Filtered out but NEVER reabsorbed

10

What colour is the top of the glucose blood test tube?

Grey

11

What is inside the glucose blood test tubes and what is its purpose?

Fluoride oxalate
Causes erythrocyte death to prevent glucose consumption

12

What is the erythrocyte sedimentation rate?

o The rate at which RBCs settle out of suspension in blood plasma, measured under standard conditions

13

What things are commonly measured in LFTs?

Albumin
Bilirubin
ALP
ALT

14

Recall 3 enzymes commonly measured when assessing liver function

Alanine aminotransferase (ALT)
Aspartate transaminase (AST)
Alkaline phosphatase (ALP)

15

What must be taken into account when measuring liver enzymes?

ALP is both a bone and a liver enzyme and so you must only measure the liver version

16

What is inside the yellow blood test tube?

Gel that promotes clotting

17

What is within the purple-top blood test tube?

Potassium EDTA

18

What is potassium EDTA used for in blood tests?

Allows 6 hours of cell survival

19

Recall one thing that can be measued using the purple-top blood tube

HbA1c

20

Which blood tube is used to assess levels of clotting factors and what is contained within it?

Blue
Citrate