Differential Diagnosis: White Lesions Flashcards Preview

Oral Pathology Exam 4 > Differential Diagnosis: White Lesions > Flashcards

Flashcards in Differential Diagnosis: White Lesions Deck (25):
1

What white lesions are due to Hyperorthokeratosis?

  • Frictional Keratosis
    • An etiologic trauma factor 
  • Snuff DIpper's Keratosis
    • Microscopically - thick layer of parakeratin 

2

What white lesions are due to Acanthosis?

Leukoedema

  • Disappears as you stretch the tissue out because it becomes thinner

3

What white lesions are due to Fibrin?

Apthous ulcers

4

What white lesions are due to coagulated epithelium?

Aspirin Burn 

  • Cauterizes or denatures the epithelial layer 
  • The protein has now coagulated and become white in color

5

What white lesions are due to an overgrowth surface of organisms? 

Candida 

  • White colonies of fungi that you can see on a PAS stain

6

What white lesions are due to Fibrosis?

Scars

  • Healed, depressed scars have less number of blood vessels and this causes them to be white

7

What is the Differential Diagnosis of White Lesions on the Buccal Mucosa? (8)

  • Cheek Biting
  • Linea Alba
  • Leukoedema
  • Hereditary Benign Intraepithelial Dyskeratosis (HBID)
  • Pachyonychia Congenita
  • Pseudomembranous Candidiasis
  • Reticular Lichen Planus 
  • White Sponge Nevus 

8

What is the basis for whiteness in Linea Alba?

Hyperkeratosis and Fibrosis

9

What is the basis for whiteness in Cheek Biting?

Hyperparakeratosis 

10

What is the basis for whiteness in Reticular Lichen Planus?

Hyperorthokeratosis

11

What is associated with Whickam Striae?

Reticular Lichen Planus

12

What is the basis for whiteness in White Sponge Nevus, HBID, and Pachyonychia Congenita?

Hyperparakeratosis and Acanthosis

Cheek biting is also due to hyperparakeratosis

  • Ask the pt is anyone in the family has it (hereditary)

13

What white lesion of the buccal mucosa can be rubbed off?

Pseudomembranous Candidiasis (Trush)

14

What is the Differential Diagnosis for a white lesion in the vestibule? (2)

  • Snuff Dipper's Keratosis
  • Chemical Cautery/Denatruation - Aspirin Burn

15

What is the Differential Diagnosis for a White Lesion on the Palate?

Nicotine Stomatitis

  • Heat of pipe smoking
  • Salivary ducts become inflamed - metaplasia 
  • "Cantelope rind"
  • Hyperkeratosis and Acanthosis

16

What is the Differential Diagnosis for a white, bald, atrophic tongue? (3)

  • Lichen Planus of dorsal tongue
  • Chronic Hyperplastic Candidiasis
  • Syphilitic Glossitis
    • Rare
    • Will turn into SCC

17

What is the Differential Diagnosis for a white patch on the lateral tongue? (4)

  • Lichen Planus
  • Hyperkeratosis
  • Dysplasia
  • Oral Hairy Leukoplakia

18

If a pt presents with a white patch on the lateral tongue and the biopsy shows Koilocytes, what do we expect it to be?

Oral Hairy Leukoplakia

  • HIV assoc 
  • Caused by EBV (herpes group)
  • Probs with lots of Candida

19

What is the Differential Diagnosis for a White Patch in the Vestibule? (5)

  • Snuff Dipper's Keratosis
  • Sanguinaria Lesion
  • Proliferative Verrucous Leukoplakia
  • Verrucous Carcinoma
  • Aspirin Burns/Chemical Cautery

20

Which white patch of the vestibule will disappear if the pt stops the habit, and which one will not go away? 

Snuff Dipper's Keratosis - within 2 weeks

Sanguinaria Lesions - does not go away