Diffuse Lung disease Flashcards
what are clinically present in interstitial lung disease
restrictive lung disease and hypoxemia on pulmonary function tests
Scaffolding of the lung, providing support for the airways, gas-exchanging units and vascular structures
Pulmonary interstititum
The central interstitial compartment extending from the mediastinum peripherally and enveloping the bronchovascular bundles is termed the
Axial interstitium
Axial interstitium is contiguous with the interstitium surrounding the small centrilobular arterieand bronchiole within the secondary pulmonary lobule, where it is called
Centrilobular intersititium
The most peripheral component of the interstitium is the
Subpleural or peripheral interstitium
Invaginations of the subpleural interstitium into the lung parenchyma from the borders of the secondary pulmonary lobules and represent the
Interlobular septa
fine network of connective tissue fibers that support the alveolar spaces
intralobular, parenchymal or alveolar interstitium
defined as that subsegment of lung supplied by three to five terminal bronchioles and separated from adjacent secondary lobules by intervening connective tissue (interlobular septa)
secondary pulmonary lobule
each terminal bronchiole subdivide into
respiratory bronchioles, alveolar ducts, alveolar sacs and alveoli
unit of lung subtended from a single terminal bronchiole is called a
pulmonary acinus
located in the center of secondary lobule
centrilobular artery, preterminal bronchiole
present at the margins of lobules within the interlobular septa, found within the contiguous subpleural interstitium
lymphatic and connective tissue
secondary pulmonary lobule is typically of what shape
polyhedral
normally 0.1 mm thick and can be seen in lung periphery, particularly along the superior and inferior pleural surfaces
interlobular septa
are V- or Y- shaped structures on thin-section CT seen within 5 to 10 mm of pleural surface
centrilobular arteries
normal airways are visible only to within ___cm of the pleura
3cm
has a diameter of 1mm and a wall thickness of 0.15 mm, not normally visible on thin-section CT
centrilobular brochiole
occassionally seen as linear or dot-like structures within 1-2 cm of the pleura and when visible, may indicate the locations of interlobular septa
pulmonary veins
normally not visible on thin section CT
peribronchovascular, centrilobular, and intralobular interstitial compartments
interlobular lines on thin-section CT are equivalent of _____ lines seen in the inferolateral portions of the lungs on frontal radiographs
Kerley B
within the central regions of the lung, long (2-6 cm) linear opacities representing obliquely oriented connective tissue septa are the equivalent of ______ lines
Kerley A
thickened intralobular lines are usually from
fibrosis, UIP, IPF
seen within the central portion of pulmonary lobule radiating outward the thickened lobular borders to produce a “spoke-and-wheel” or “spider web” appearance
intralobular septa
nodular fissural thickening are usually seen in
sarcoidosis and lympangitic carcinomatosis