digestion and absorption Flashcards

1
Q

what is starch digested by

A

amylase

membrane-bound disaccharides

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2
Q

describe how starch is digested by amylase and membrane-bound disaccharides

A
  • amylose hydrolyses starch to maltose
  • membrane-bound maltase hydrolyses maltose to glucose
  • glycosidic bond is hydrolysed
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3
Q

where is amylase produced and what is it released into

A
  • salivary glands, into mouth

- pancreas, into small intestine

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4
Q

starch to maltose

maltose to glucose

A

polysaccharide to disaccharide

disaccharide to monosaccharide

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5
Q

describe how disaccharides are digested

A

membrane-bound disaccharides hydrolyse disaccharide into 2 monosaccharides
hydrolysis of glycosidic bond

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6
Q

what is galactose hydrolysed to

A

glucose

lactose

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7
Q

what is sucrose hydrolysed to

A

glucose

fructose

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8
Q

what is maltose hydrolysed to

A

glucose

glucose

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9
Q

describe how lipids are digested

A
  • bile salts produced in liver
  • bile salts emulsify lipid to smaller lipid droplets
  • lipase, made in pancreas, released to small intestine
  • lipase hydrolysis lipids into monoglycerides + fatty acids
  • breaking ester bond
  • monoglycerides + fatty acids + biles salts stick together to form micelles
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10
Q

why do bile salts emulsify lipids into smaller lipid droplets

A

to increase surface area of lipids

to speed up action of lipases

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11
Q

where is lipase made and where is it released to

A

pancreas, into small intestine

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12
Q

what 3 enzymes digest proteins

A

endopeptidases
exopeptidases
dipeptidases

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13
Q

how do endopeptidases digest proteins

A

hydrolyse peptide bonds within protein

breaking protein into 2 or more smaller peptides

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14
Q

how do exopeptidases digest proteins

A

hydrolyse peptide bonds at end of protein

removing a single amino acid

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15
Q

how do dipeptidases digest proteins

A

often membrane-bound in ileum

hydrolyses peptide bond between dipeptide= 2 amino acids

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16
Q

Describe the mechanism for absorption of monosaccharides and amino acids by the cells lining the ileum.

A
  • Sodium ions actively transported out of epithelial cells lining the ileum, into the blood, by the sodium-potassium pump. Creating a concentration gradient of sodium (higher conc. of sodium in lumen than epithelial cell)
  • Sodium ions and glucose move by facilitated diffusion into the epithelial cell from the lumen, via a co-transporter protein
  • Creating a concentration gradient of glucose – higher conc. of glucose in epithelial cell than blood
  • Glucose moves out
17
Q

Describe the mechanism for absorption of lipids by the cells lining the ileum.

A

-Monoglycerides and fatty acids diffuse out of micelles (in lumen) into epithelial cell
Because lipid soluble

  • Monoglycerides and triglycerides recombine to triglycerides which aggregate into globules
  • Globules coated with proteins to form chylomicrons
  • Leave via exocytosis and enter lymphatic vessels
  • Return to blood circulation