Digestion and Absorption Flashcards

1
Q

What is the primary function of the digestive system?

A

To break down food molecules and absorb water.

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2
Q

What do digestive juices contain that facilitate digestion?

A

Hydrolytic enzymes and other molecules.

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3
Q

What is the process by which large insoluble food molecules are converted into smaller soluble molecules?

A

Hydrolysis.

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4
Q

What enzymes hydrolyse polypeptides and proteins into amino acids?

A

Proteases.

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5
Q

What enzymes are responsible for hydrolysing carbohydrates into simple sugars?

A

Carbohydrases.

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6
Q

Which enzymes hydrolyse fats into glycerol, fatty acids, and monoglycerides?

A

Lipases.

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7
Q

What enzyme do salivary glands secrete?

A

Salivary Amylase.

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8
Q

What is the role of gastric juice in the stomach?

A

It is acidic, kills microorganisms, and contains endopeptidases and exopeptidases.

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9
Q

Where does the majority of nutrient absorption occur?

A

In the small intestine (ileum).

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10
Q

What enzyme hydrolyses maltose to glucose in the small intestine?

A

Maltase.

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11
Q

Complete the sentence: In mammals, cellulose is NOT hydrolysed because _______.

A

the enzyme cellulase is not produced.

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12
Q

What are the products of starch digestion?

A

Maltose and glucose.

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13
Q

Which two types of enzymes are involved in protein digestion?

A

Endopeptidases and exopeptidases.

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14
Q

What is the function of dipeptidases?

A

To hydrolyse dipeptides into amino acids.

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15
Q

What type of transport do monosaccharides use to cross the epithelial cell membrane?

A

Facilitated diffusion and co-transport.

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16
Q

True or False: Glucose absorption requires ATP directly.

A

False.

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17
Q

What is the role of bile in lipid digestion?

A

To emulsify fat droplets and increase the surface area for lipase action.

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18
Q

What are micelles and their function in lipid absorption?

A

Micelles make fatty acids soluble in water and transport them to the epithelial cell surface.

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19
Q

How are chylomicrons formed?

A

Triglycerides are modified and packaged with proteins at the Golgi apparatus.

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20
Q

What is the outcome of lipid digestion in the small intestine?

A

Lipids are hydrolysed into glycerol, fatty acids, and monoglycerides.

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21
Q

How are amino acids absorbed from the ileum into the blood?

A

By facilitated diffusion and co-transport using specific carrier proteins.

22
Q

Fill in the blank: Proteins are hydrolysed by _______.

A

Proteases.

23
Q

What happens to sodium ions if they are not actively transported out of the epithelial cell?

A

The concentration of sodium ions will rise in the cell.

24
Q

What is the order of the digestive system (process)?

A

Ingestion
Digestion
Absorption
Egestion

25
What enzyme do salivary glands secrete and what does this hydrolyse?
Salivary glands –secretes salivary amylase which hydrolyses starch to maltose.
26
What does the pancreas secrete?
Pancreatic juice containing: amylase endopeptidase exopeptidase lipase
27
What has the small intestine been adapted for?
It has many ileum to provide a large surface area for the absorption of the products of digestion Maltase enzymes are embedded in the epithelial cell membrane of the small intestine to hydrolyse maltose to glucose, so it is available for rapid absorption
28
Why is having maltase enzyemes embedded in the epithelial cell membrane of the small intestine a benefit?
To hydrolyse maltose to glucose so that it is available for rapid absorption
29
Define digestion
A process in which large molecules are hydrolysed by enzymes into small molecules, which can be absorbed into the blood and then assimilated into biological molecules
30
Describe the digestion of starch
1. Food enters the mouth and is mechanically digested 2. Salivary amylase hydrolyses glycosidic bonds in the starch to produce maltose 3. In the small intestine, pancreatic amylase hydrolyses more starch into maltose 4. Maltose is hydrolysed into glucose by maltase
31
Where is maltase located?
The epithelial cell membrane of the ileum
32
How are monosaccharides absorbed?
By facilitated diffusion and co-transport
33
How are amino acids absorbed?
By facilitated diffusion and co-transport
34
Describe how glucose is absorbed from the ilium into the blood
1. Sodium ions are actively transported out of epithelial cell into the blood by sodium potassium pump; 2. This creates a concentration gradient of Na+ 3. Na+ and glucose enter by facilitated diffusion using co-transport 4. Na+ diffuse into the cell down its concentration gradient. 5. Glucose moves into the cell against its concentration gradient 6. Glucose moves into the blood by facilitated diffusion
35
Describe how amino acids are absorbed from the ilium into the blood
1. Sodium ions are actively transported out of epithelial cell into the blood by sodium potassium pump; 2. This creates a concentration gradient of Na+ 3. Na+ and amino acids enter by facilitated diffusion using co-transport 4. Na+ diffuse into the cell down its concentration gradient. 5. Amino acids move into the cell against its concentration gradient 6. Amino acids moves into the blood by facilitated diffusion
36
What do epithelial cells contain a lot of, for more active transport?
Many mitochondria to produce a large amount of ATP
37
Why can't some people hydrolyse lactose?
They do not produce lactase
38
How does lactose and disaccharides lower water potential?
They are soluble
39
Lactose and disaccharides are soluble, what does this mean?
They lower water potential
40
Describe protein digestion
1. Proteins are hydrolysed by protease. 2. Endopeptidases hydrolyse the peptide bonds within the polypeptide chain. 3. This produces many smaller polypeptide chains and increases the surface area for the next enzyme. This makes digestion faster and more efficient. 4. Exopeptidases hydrolyse the peptide bonds at the terminal ends of the protein, removing one amino acid at a time. Amino acids and dipeptides are produced. 6. Then dipeptidases hydrolyse dipeptides into amino acids which can now be absorbed by facilitated diffusion, active transport and cotransport.
41
What are exopeptidases?
Specific: one group are complementary to the N terminal end and another group are complementary to the C terminal end.
42
Where are dipeptidases located?
embedded in the cell surface membrane of the epithelial cells
43
Where are lipids digested?
ONLY within the lumen of the ileum
44
Where is bile produced?
Liver
45
Where is bile stored?
The gall bladder
46
What does bile contain?
Bile salts, which emulsify fat droplets
47
Why is it good that bile salts emulsify fat droplets?
It increases the surface area of the lipids for the action of lipases
48
What do lipases hydrolyse lipids into?
Glycerol Fatty acids Monoglycerides
49
Describe lipid digestion
1. Lipid droplets are mixed with bile salts to form smaller droplets; 2. Smaller droplets increase surface area for faster hydrolysis by lipase; 3. Triglycerides hydrolysed into glycerol, fatty acids and monoglycerides; 4. BILE SALTS, Glycerol and fatty acids form micelles;
50
Describe lipid absorption
5. Micelles make Fatty acids soluble in water and bring Fatty acids to the surface of the epithelial cell membrane. 6. Fatty acids enter the epithelial cell by simple diffusion. 7. At the Smooth.E.R→Fatty acids, glycerol are recombined to form triglycerides. 8. At the golgi apparatus →Triglycerides are modified, proteins are added to form lipoproteins and packaged into vesicles. 9. Lipoproteins are transported into a lymph vessel by exocytosis. They then enter the blood.