Digestive Part II - slides 1 - 68 Flashcards Preview

AP II B5 Digestive > Digestive Part II - slides 1 - 68 > Flashcards

Flashcards in Digestive Part II - slides 1 - 68 Deck (125)
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1

Heaviest gland of the body?

Liver (3lbs)

2

Largest INTERNAL organ of the body?

Liver

3

Located inferior to the diaphragm, the Liver occupies most of the ___ _____ and part of epigastric region

Right Hypochondriac region

4

The Liver, almost completely covered by visceral peritoneum

Divided into two principal lobes by the ___ ____

Falciform Ligament

5

Which lobe of the Liver is smallest?

Right lobe Largest

Left lobe smallest

6

The Liver receives blood from two sources:

Hepatic artery (25%) – oxygenated blood

Portal vein (75%) – deoxygenated blood + nutrients

7

These compose the ___ ___:
-Bile ducts inside the liver
-Common hepatic duct (outside of the liver)
-The gallbladder and its cystic duct
-Common bile duct
-Ducts of the pancreas

Biliary Tree

8

Functions of the Biliary Tree: (3)

1. Make, store, and secrete bile
2. Rids liver (and body) of some waste products
3. Aids in digestion of foods in small intestine

9

Major functional unit of the Liver:

Hepatic Lobules

10

Hexagonal in shape

Comprise rows of hepatocytes

Perform a wide array of metabolic, secretory, and endocrine functions

Hepatic Lobules

11

Found in the corners of the Hepatic Lobules:

Portal Triads

12

These all comprise ___ ____:
-A bile duct (flows away from central vein)
-Branch of hepatic artery (flows toward central vein)
-Branch of portal vein (flows toward central vein)

(see slide 7)

Portal Triads

13

Specialized epithelial cells interspersed throughout the liver
Make up ~80% of the mass of the liver

Hepatocytes

14

Forms a crucially important cell layer that separates sinusoidal blood from the canalicular bile

Hepatocytes

15

Location of synthesis of:
-Many transport proteins like albumin, and fibrinogen
-Lipoproteins, fatty acids, triglycerides
-Cholesterol
-Bile

Hepatocytes

16

Highly permeable blood capillaries between rows of hepatocytes

Hepatic Sinusoids

17

Hepatic Sinusoids:

Receives oxygenated blood from branches of ___ ___

Receives nutrient rich deoxygenated blood from the ___ ___

Hepatic Artery

Portal Vein

18

Fixed phagocytes found within sinusoids that help “clean” blood

Destroy worn-out red and white bloods cells, bacteria, and other foreign matter

Stellate reticuloendothelial (Kupffer) cells**

19

Functions of the Liver:
-Carbohydrate (starch) metabolism
-Lipid Metabolism
-Protein Synthesis
-Processes Drugs and -Hormones
-Excretion of Bilirubin
-Storage
-Phagocytosis
-Bile Synthesis

...further explained in other cards

20

Carb Metablolism:
Plasma glucose is low:

Glycogenolysis

21

Carb Metabolism:
Plasma glucose is high:

Glyconegesis

22

What function of the Liver involves:
Synthesizes and stores some triglycerides
Synthesizes certain lipoproteins
Synthesizes some cholesterol
-Adds some cholesterol to bile to aid in lipid metabolism

Lipid Metabolism

23

Bilirubin is reabsorbed from broken down RBC’s and excreted in the ___ produced within the liver

Bile

24

Most of the bilirubin in bile is metabolized in the __ ___ by bacteria and eliminated in feces

Small Intestine

25

In addition to glycogen, liver is prime site for storage of certain vitamins such as __, __, __, __ , __,

Also stores certain minerals such as ___ and ___.

These are all released when needed by the body

A, B12, D, E, K

Iron and Copper

26

The stellate reticuloendothelial (Kupffer) cells phagocytize aged RBC’s, WBC’s and some bacteria

Liver function: Phagocytosis

27

Bile synthesis involves the mixture of bile salts, ____ and ____

Bile Pigments and Cholesterol

28

Each day about how much bile is synthesized and secreted by hepatocytes:

600 - 1000mL

29

Bile is stored and concentrated in the:

Gallbladder

30

Bile is a yellow, brownish, or olive-green liquid

pH of ___-___

Plays important role in fat digestion and absorption

Serves as a means for excretion of waste products from blood (i.e. ____)

pH 7.6 - 8.6

i.e. blilirubin