Digestive System: Glandular portion Flashcards
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describe the organization of the exocrine pancreas?
stroma, parenchyma, duct pattern (intercalated ducts>intralobar ducts>interlobular ducts)
what part of the exocrine pancreas is there a high rate of protein synthesis? so with this, is it basophilic or eosinophilic? describe the gland
parenchyma
compound tubuloacinar gland made of serous cells
where are the bulk of digestive enzymes located? be specific; name these enzymes; what do all enzymes here secrete
parenchyma of the exocrine pancreas
trypsinogen and chymotrypsinogen, proteases in zymogen form
ribonuclease
pancreatic lipase
pancreatic amylase
alkaline sodium bicarbonate solution
what is the endocrine portion of the pancreas also known as? how are they arranged?
islets of langerhans
clumps with AUTONOMIC fibers
what cell types are found in the endocrine pancreas?
alpha, beta, and delta (enough released for a localized effect, modulate release of insulin and glucagon)
important metabolic functions of the liver?
lipid, protein and carbohydrate digestion, drug detox, formation of blood albumins and clotting factors, vitamins and mineral storage, removal of senescent RBC and bile production
what is the hepatocyte in contact with?
a sinusoid and a bile canaliculus
sinusoids of the hepatic lobule produce these cells?
Kuppfer cells and stellate cells
these cells are fixed macrophages found lining the sinusoids and responsible for RBC recycling?
kuppfer cells
not visible with normal staining technique and store vitamin A
stellate cell
describe the blood flow into the central canal? what about for bile production
mixing of blood from the portal vein and hepatic artery into the hepatic sinusoids than into the central canal flowing out of the liver
hepatocytes secrete directly into the bile canal dumping into the bile duct
describe the hepatic lobule?
central vein surrounded by sinusoids, where it has discontinuous epithelium and basal lamina which allows everything but blood to leave the sinusoids and enter the space of Disse
this is allows for more access to material via spaces from the blood?
space of Disse
this is an elongated tapering organ suspended from eh inferior surface of the liver and stores bile within the small intestine?
gallbladder
what layers comprise the gallbladder?
mucosa and muscularis externae