Diseases of Larynx and Pharynx Flashcards

(78 cards)

1
Q

Sore throat

common causes

A

MC = viral
Group A strep (strep pharyngitis 15%)
EBV/Monoucleosis

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2
Q

Pharyngitis and Tonsillitis

A

50% of outpatient antibiotic use - inappropriate usually bc VIRAL cause

augmentin/ Amox MC used

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3
Q

Failure to recognize and treat Group A strep infection risk of

A

rheumatic fever and glomerulonephritis

May progress into a Peritonsillar abscess

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4
Q

Viral Pharyngitis

A

MC cause sore throat

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5
Q

Viral Pharyngitis - s/s

A

Odynophagia (painful swallowing)
F/muscle aches
tender/swollen lymph nodes
+/- exudates

cough!
nasal congestion/coryza/sneezing

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6
Q

Viral Pharyngitis - Dx

A

rapid strep test
throat culture

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7
Q

Viral Pharyngitis - Tx

A

conservative tx

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8
Q

Strep Pharyngitis (centor criteria)

A
  • Fever >38
  • tender ant. cervical adenopathy
  • lack of cough
  • pharyngo- tonsillar exudate

+/- 1 point for age

all 4 = strongly suggest GABHS
3/4 = sensitivity of rapid tests >90%
1/4 = GABHS unlikely

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9
Q

Strep Pharyngitis (CDC suggestions)

A

0-1 : no culture or test; no abx
2-3 : throat culture OR rapid test; + = abx
4 : high risk GABHS; tx w/o test

if hoarsness, cough or coryza present = NOT likely strep

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10
Q

Strep Pharyngitis - Dx

A

rapid strep test
culture

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11
Q

Strep Pharyngitis - Tx

A

Benzathine IM (painful)
Pen V

AMOX BID 10 days

erythro, azithro, cephalosporin if PCN allergy

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12
Q

Strep Pharyngitis - Complications

A

scarlet fever
glomerulonephritis,
abscess,
rheumatic fever

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13
Q

Strep Pharyngitis - s/s

A

Sudden onset sore throat
Fever
Tonsillopharyngeal &/or uvular edema
Anterior cervical adenitis
Scarlatiniform skin rash (scarlet fever)

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14
Q

Infectious Mononucleosis

A

EBV (HHV4) - blood test IgM, IgG
MC 12-19 y/o (but any age)

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15
Q

Infectious Mononucleosis - transmission

A

saliva
“kissing dz”

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16
Q

Infectious Mononucleosis - s/s

A

F
severe sore throat
POSTERIOR CERVICAL ADENOPATHY
tonsillar exudate
malaise
SPLENOMEGALY (about 50% cases)
photophobia

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17
Q

After effects of mono

A

Painful Cervical Adenopathy x weeks

large, firm cervical adenopathy – history is important!

unresolved after weeks - LN biopsy (FNA or excision is best) to rule out things like lymphoma

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18
Q

Infectious Mononucleosis - Dx

A

clinical!

Monospot

EBV test (IgM - acute; IgG - 4 weeks after)

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19
Q

Infectious Mononucleosis - Tx

A

95% improve w/o specific tx

NSAIDS, acetaminophen

salt water rinses/gargles

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20
Q

Infectious Mononucleosis - education

A

No contact sports until splenomegaly is resolved!
Reduce the risk of splenic rupture

Fever and sore throat resolve in 7-10 days

Lymphadenopathy and splenomegaly may persist >4 weeks

Significant fatigue for 2-3 months

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21
Q

Infectious Mononucleosis - complications

A

hepatitis
myocarditis,
encephalitis

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22
Q

Corynebacterium Diphtheriae

A

Diphtheria (Gram+, club shaped rod)

Transmitted via respiratory secretions

MC attacks resp tract

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23
Q

Corynebacterium Diphtheriae s/s

A

Nasal infxn = nasal discharge

Laryngeal infxn - upper airway and bronchial obstruction

Pharyngeal infxn - MC = tenacious gray membrane covering the tonsils/pharynx

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24
Q

Corynebacterium Diphtheriae - complications

A

Myocarditis
Neuropathy

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25
Corynebacterium Diphtheriae - Dx
clinical culture to confirm
26
Corynebacterium Diphtheriae - Tx
horse serum antitoxin must be given in all cases of diphtheria (CDC) ENT (laryngoscopy) - remove membrane if airway obstruction oral abx - PCN or erythro Isolate until 3 - pharyngeal cultures vaccine to prevent
27
Pharyngitis- Other Causes
N. Gonorrhea (STD of pharynx, direct contact) HSV (very painful, "whitish" ulcerations post. oropharynx; gums gray and slough) Coxsackie virus (Hand, Foot, Mouth) -
28
Abnormal Voice Sounds Dysphonia
impairment in the ability to produce sound with the vocal organs
29
Any abnormal voice sounds = A GOOD H&P!
tobacco use? laryngeal CA? lung CA w/ paralysis recurrent laryngeal n? weight loss? onset >2 weeks = ENT w/ laryngoscopy
30
Hoarseness
Abnormal vibration/flow of air past the vocal folds/cords
31
Hoarseness types
Breathy Harsh Rough, low-pitched
32
Hoarseness causes
Acute Laryngitis Chronic Laryngitis Overuse Benign vocal fold lesions - nodules, polyps Laryngeal cancer Neurologic dysfunction
33
Hoarseness Referral recommendations
Persistent symptoms > 2 weeks OR if any concern for serious underlying cause OR with any associated symptoms such as: Hemoptysis Dysphagia Odynophagia Otalgia airway compromise
34
Stridor
high-pitched breath sounds produced by a narrowed or obstructed airway timing and rapiditiy of onset KEY ALL CASES NEED EVAL must rule out foreign body
35
Inspiratory stridor
narrowing AT or ABOVE the vocal cords
36
Expiratory or mixed (biphasic) stridor
BELOW the vocal cords
37
Acute Laryngitis
Any inflammatory process that affects the larynx
38
Acute Laryngitis MC cause of
hoarseness (hallmark symptom)
39
Acute Laryngitis S/S
Hoarseness, Aphonia Reduced vocal pitch Associated URI symptoms- cough
40
Acute Laryngitis - Tx
Supportive therapy Bacterial- oral antibiotics Oral/IM steroids?
41
Laryngopharyngeal Reflux (LPRD)
Chronic laryngitis GERD into larynx
42
Laryngopharyngeal Reflux (LPRD) S/S
throat clearing, throat discomfort, chronic cough, postnasal drip, esophageal spasm <50% heartburn excess mucus in throat increased rhinorrhea
43
Laryngopharyngeal Reflux (LPRD) DX
ENT referral laryngoscopy critical to exclude other causes hoarsness (tumors/ nodules) + response to empiric PROTON PUMP INHIB Therapy decrease spicy foods, tomato based foods
44
Peritonsillar Abscess (Quinsy) Dx
Imaging CT Confirmed aspiration of pus = ENT
45
Peritonsillar Abscess (Quinsy)
Penetration of infection through the tonsillar capsule and into adjacent tissue
46
Peritonsillar Abscess (Quinsy) S/S
severe sore throat Trismus (limited ability to open mouth, due to spasm) Muffled "hot potato" voice deviation of soft palate and uvula (normal side)
47
Peritonsillar Abscess (Quinsy) Tx
Abx tolerate PO = oral abx unable tolerate PO + more severe s/s = Admit + IV abx Tonsillectomy if more than 2x - indicated for recurrence Needle aspiration I&D
48
Epiglottitis (supraglottitis)
Acute, rapidly progressive cellulitis of the epiglottis and surrounding tissue that can lead to airway compromise MC in DM and kids (2-5 y/o)
49
Epiglottitis (supraglottitis) cause
viral or bacterial
50
Epiglottitis (supraglottitis) S/S
4 D's - Drooling - Dysphagia - Dyspnea - Dysphonia (hot potato voice) Tripod position f/c
51
Epiglottitis (supraglottitis) Dx
THUMB PRINT SIGN - lateral x-rays soft tissue Laryngoscopy - ENT + anesthesia = spasm and airway compromise
52
Epiglottitis (supraglottitis) Tx
Keep the patient comfortable! DO NOT use a tongue depressor respiratory distress, = intubate and secure the airway! ADMIT IV abx - cephalosporins IV steroids - dexamethasone Close airway obsevation Continuous pulse ox prep intubate
53
Vocal Cord Nodules
Smooth, PAIRED lesions at the junction of the anterior 1/3 and posterior 2/3 due to vocal abuse/ overuse common cause of hoarsness
54
Vocal Cord Nodules - TX
Modification of voice habits (most resolve) Referral to speech therapy Do not resolve = surgery ?
55
Vocal Fold Polyps
UNILATERAL masses within the superficial lamina propria Typically larger than nodules due to vocal trauma (resolution of cord hemorrhage)
56
Vocal Fold Polyps - TX
Vocal rest, steroids for small polyps Excision- larger polyps
57
Vocal Fold Cysts
Traumatic lesions from mucus-secreting glands on the inferior aspect of vocal folds vary in size and degree of symptoms
58
Vocal Fold Cysts - tx
rarely resolve completely - often scar (permenant dysphonia) Surgical intervention to prevent scarring by preserving the mucosal layer
59
Recurrent Respiratory Papillomatosis
benign, rare malign symptomatic and causes hoarness MC in kids
60
Recurrent Respiratory Papillomatosis cause
HPV type 6 & 11
61
Recurrent Respiratory Papillomatosis Tx
Failure to tx= distal spread and airway compromise Tx: repeated laser vaporizations or resections Severe cases = airway compromise in adults and may require treatment every 6 weeks
62
Polypoid Corditis loss of ...
elastin fibers and loosening of intracellular junctions within the lamina propria = swelling of superficial lamina (REINKE EDEMA)
63
Polypoid Corditis strong assoc. w/
SMOKING vocal abuse, chemicals, hypothyroid
64
Polypoid Corditis Tx
Surgical resection if stridor or airway obstruction
65
Vocal Cord Paralysis
lesion or damage to either the vagus or recurrent laryngeal nerve (RLN) breathy dysphonia or effortful voicing
66
Vocal Cord Paralysis - diff types
Unilateral recurrent laryngeal nerve injury Unilateral Vagus damage/lesions BILATERAL fold paralysis = Medical Emergency!
67
Vocal Cord Paralysis Dx
CT/MRI with contrast of brain and brainstem Direct visualization with laryngoscope
68
Vocal Cord Paralysis Tx
create safe airway with normal vocal ability Vocal cord injections with ProLaryn (dermal filler) Vocal cord prosthesis - Thyroplasty (Montgomery Implant)
69
Laryngeal Leukoplakia
Commonly associated with hoarseness in smokers Histology = mild, moderate or severe dysplasia 35-60% with severe dysplasia = squamous cell carcinoma
70
Laryngeal Leukoplakia - tx
Proton Pump Inhibitors, regular surveillance, resection and/or radiation Smoking cessation (mild/mod)
71
Squamous Cell Carcinoma of the Larynx
MC malign of larynx Occurs almost exclusively in smokers MEN, 50-70 y/o Associated with HPV 16 and 18
72
Squamous Cell Carcinoma of the Larynx S/S
Change in voice quality (new/persist hoarsness >2 weeks in smoker) neck mass throat/ear pain
73
Squamous Cell Carcinoma of the Larynx Dx
Laryngoscopy with BIOPSY Lung function and exercise tolerance should be evaluated prior to surgery due to risk of aspiration following procedure for resection
74
Squamous Cell Carcinoma of the Larynx Staging
TNM - tumor, node, metastasis
75
Squamous Cell Carcinoma of the Larynx Tx goals
Cure Preserve swallowing and voice Avoid permanent Tracheostoma
76
Squamous Cell Carcinoma of the Larynx Modalities
Radiation Chemo Surgical resectino Long term f/u
77
Laryngectomy
Removal of the larynx (voice box)
78
Laryngectomy - after
patients can eat by mouth Permanent stoma – safest airway Speech? Tracheoesophageal Puncture + Prosthesis Electrolarynx (robot voice from smokers commercial)