Diseases of the Mouth and Salivary Gland Flashcards

(143 cards)

1
Q

Aphthous Ulcers

A

AKA Canker sore

? associated with human herpes virus 6
STRESS is a major predisposing factor!

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2
Q

Aphthous Ulcers Common location

A

Typically found on buccal and labial mucosa
Spares gingival and palatal mucosa

Common & easy to identify

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3
Q

Aphthous Ulcers S/S

A

Single or multiple
Often recurring
Painful
Small, round ulcerations with yellow-gray
centers surrounded by red halos

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4
Q

Aphthous Ulcers Tx

A

Minor (<1cm)—generally heal, 10 -14 days
Major (>1cm)—can be disabling due to pain

  • If large or not improving, consider biopsy

Symptom care
Salt water or medicated rinses (swish and spit)
Cimetidine (Tagamet) has been helpful in patients with recurrent ulcers

!! Topical steroids (triamcinolone, in adhesive base (Orobase))

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5
Q

Aphthous Ulcers

Large or persistent areas may be caused by

A

erythema multiforme, drug allergies, HSV, bullous or pemphigus diseases, Behcet disease or inflammatory bowel disease

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6
Q

Necrotizing Ulcerative Gingivitis

A

AKA “Trench Mouth” and Vincent Angina”

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7
Q

Necrotizing Ulcerative Gingivitis - cause

A

infection of the gums with spirochetes & fusiform bacteria

sudden onset

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8
Q

Necrotizing Ulcerative Gingivitis - common in

A

young adults in times of stress

underlying systemic disease

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9
Q

Necrotizing Ulcerative Gingivitis - S/S

A

Gums - tender and inflamed

Affected gingiva between teeth ulcerates and may be covered with a gray exudate which can be removed with gentle pressure

F/tender, bleeding gums, halitosis and cervical lymphadenopathy

bad smelling breath

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10
Q

Necrotizing Ulcerative Gingivitis - Tx

A

Warm half-strength peroxide rinses or other antibacterial rinses

Oral antibiotics- Penicillin and Metronidazole

Debridement ?

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11
Q

Herpes Stomatitis - type and cause

A

HSV Type 1

Prodrome: burning/tinging

Then, small vesicles form that rupture and form scabs

Problematic in the HIV population- more frequent and potentially severe

stress can bring this on

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12
Q

Herpes stomatitis - lesion location

A

attached gingiva and mucocutaneous junction of lip, tongue, buccal mucosa and soft palate

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13
Q

Herpes stomatitis -

Primary infxn symptoms

A

malaise, fever, headache and cervical lymphadenopathy

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14
Q

Herpes stomatitis -

Recurrences

A

usually occur on the LIPS

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15
Q

Herpes stomatitis - Tx

A

Adults : common, mild and short-lived; typically requires no intervention - symptomatic care

oral acyclovir, valacyclovir (or topical)

(Usually only effective if started within 24-48 hours of onset of symptoms)

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16
Q

Primary syphilis

A

Chancre

Single, indurated painless ulcer on the mucosa

Resolves spontaneously, 4 - 6 weeks

bx can help with dx

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17
Q

Secondary Syphilis

A

a well-defined white plaque on the labial or palatal mucosa =

(CONDYLOMA LATA)

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18
Q

Oral Candidiasis cause

A

overgrowth of candida species

MC in either systemic or local immunosuppression!

(steriods, chemo/rad, abx use, HIV, DM, dentures)

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19
Q

Oral Candidiasis - common in

A

the elderly and very young

individual who use powder inhalers (Recommend rinsing, swishing and spitting after use)

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20
Q

Oral candidiasis - tongue blade use

A

DOES scrape off and reveals eryth. base

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21
Q

Oral candidiasis - S/S

A

Throat or mouth pain

Erythema of the oral cavity, Creamy, white patches/plaques

May have associated burning, may be worse with certain foods/drink

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22
Q

Oral candidiasis - Dx

A

Clinical

wet prep/bx if needed

Consider HIV testing

HIV + pts, oral exam every visit & dental visits every 6 mos.

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23
Q

Oral candidiasis - Tx

A

Antifungal therapy

Topical: Clotrimazole troches or Nystatin solution (1st line usually)

Oral: Fluconazole, Ketoconazole (not common)

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24
Q

Oral candidiasis can spread

A

down esophagus and throat/pharynx

same tx - swish and swallow

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25
Mucoceles
Cystic lesions found in the mouth, usually lower lip (oral mucousa!) Common, benign develop following trauma (self-biting) or obstruction of a minor salivary gland
26
Mucoceles - S/S
Variable in size, contains gelatinous fluid Nodule, with a thick roof Chronic lesions = firm, inflamed, poorly circumscribed nodules; bluish, translucent; fluctuant
27
Mucoceles - Dx
clinical, biopsy if needed
28
Mucoceles - Tx
Avoid any further trauma = resolution Excision if not improving, bothersome or progressing
29
Ranula
found under tongue! May be small and well circumscribed or “plunging” similar to mucocele
30
Ranula - tx
can be excised but need to go down to base to avoid recurrence resolve on their own if small usually
31
Glossitis
Inflammatory disorder of the tongue loss of filiform papillae rarely painful
32
Glossitis - Appearance
smooth, glossy appearance with red or pink background
33
Glossitis - causes
Nutritional deficiencies (B12, Niacin, Riboflavin, Iron, Vit E) Drug reactions Dehydration Malnutrition- protein/calorie deficit Certain irritating foods and liquids Autoimmune disorders- Sjogren’s, Celiac
34
Glossitis - Tx
underlying cause / improve nutritional diet
35
Glossodynia
AKA “Burning Mouth Syndrome" or burning tongue Burning and pain of the tongue +/- glossitis MC in post-menopausal women
36
Glossodynia - associated with
Diabetes Mellitus Drugs (diuretics) Tobacco Xerostomia (dry mouth) Candidiasis
37
Glossodynia - Tx
underlying causes, change long-term meds, smoking cessation Meds (if needed): clonazepam Behavioral therapy may be helpful If occurring on only one side of tongue, neurologic lesions need to be ruled out
38
Fissured tongue
Deep grooves located on the midline or evenly distributed on the tongue surface Can be a normal tongue variant seen in adults
39
Fissured tongue - Tx
generally asymp. although if irritation from entrapped debris occurs, brushing the tongue may be helpful
40
Fissured tongue - associated w/
malnutrition, Down Syndrome, Vitamin B deficiency predisposing factor for halitosis
41
Black tongue
Hyperpigmentation of the tongue and oral mucosa commonly seen in dark-skinned individuals
42
Black Tongue - less common causes
drugs (tetracyclines, bismuth subsalicylate) proton pump inhibitors Addison disease pellagra (niacin deficiency)
43
Black Hairy Tongue
harmless, temporary cond. - tongue discoloration Buildup of dead cells on the papillae papillae easily trap bacteria, yeast, tobacco, food or other substances
44
Black Hairy Tongue - tx
Resolves by eliminating cause & by practicing good oral hygiene
45
Angular Chelitis
Acute or chronic inflammation of the labial mucosa at the lateral commissures
46
Angular Chelitis - Causes
Excessive moisture from saliva - (secondary infxn = candidiasis or S. aureus) More common in older age, denture wearers, poor oral hygiene Nutritional deficiencies, in younger patients- lip licking, thumb sucking, drooling
47
Angular Chelitis - S/S
Erythema, maceration, scaling, fissuring painful, usually bilateral ulceration, crusting, cracking
48
Angular Chelitis - Dx
clinical culture? KOH prep?
49
Angular Chelitis - Tx
improve denture fit/hygiene, optical oral hygiene, barrier creams/ointment, topicals
50
Geographic tongue
AKA benign migratory glossitis Recurrent inflammatory disorder - unknown etiology - affects the dorsum of the tongue areas of atrophy lesions change location, pattern, size, and migrate
51
Geographic tongue - s/s
usually asymp. sometimes sensitive or painful w/ certain foods/ drinks may be associated w/ atopy, psoriasis, or reactive arthritis
52
Geographic tongue - Dx
clinical bx for DDX
53
Geographic tongue - Tx
none necessary
54
Hairy Leukoplakia
NOT premalignant common early finding of HIV also seen in organ transplant pts
55
Hairy Leukoplakia - cause
EBV
56
Hairy Leukoplakia - appearance and location
Slightly raised leukoplakic areas with a “hairy” surface commonly lateral border of tongue
57
Hairy Leukoplakia - Tx
nonspecific improves w/ antiretroviral meds to treat HIV
58
Gingival hyperplasia
develop as a result of inflammation in response to long-standing gingivitis in children OR due to certain medications
59
Gingival hyperplasia - medication causes
phenytoin, cyclosporine, calcium channel blockers
60
Gingival hyperplasia - tx
if isolated - consider bx
61
Gingivitis
MC form of periodontal gum dz (precursor to periodontitis)
62
Gingivitis - S/s
Inflammatory (red/ swelling) bleeding may occur w/ brushing/flossing
63
Gingivitis - Tx
Good, regular, oral hygiene Regular dental check-ups and removal of tartar/plaque
64
Periodontitis
Gingival inflammation accompanied by loss of supportive connective tissue chronic form MC in adults - lead to destructino of periodontium and tooth loss
65
Dental Caries - cause
microbs that make acids on tooth surface from di/monosaccharides demineralization of enamel tooth decay
66
Dental Caries - S/S
initially asymp. pain temp. sensitivity
67
Dental Caries - Tx
filings
68
Dental Caries - prevention
regular dental care (fluoride toothpaste) dietary changes
69
Dental Abscess
Infxn, pocket of pus, around tooth - untreated cavity, an injury or from prior dental work
70
Dental Abscess - periapical
tip of root
71
Dental Abscess - periodeontal
in the gums at the side of the tooth root
72
Dental Abscess - s/s
toothache temp. sensitivity swelling face/cheek swollen/tender lymph nodes
73
Dental Abscess - Dx
X-rays, CT for extent of infxn (can lead to airway compromise if untxed)
74
Dental Abscess - Tx
oral abx abx rinses I&D, root canal, dental extraction page Dentistry not ENT
75
Ludwig's Angina
Suppurative odontogenic infection which extends to the facial spaces BILATERAL submandibular spaces!!
76
Ludwig's Angina - s/s
Usually secondary to infected 2nd or 3rd mandibular molar Aggressive, rapidly spreading cellulitis WITHOUT lymphadenopathy WITH potential for airway obstruction
77
Ludwig's Angina - Dx
clinical CT imaging of choice palpate floor of mouth!! which should be elevated
78
Ludwig's Angina - Tx
1st- MANAGE AIRWAY IV abx if abscess - drain
79
Leukoplakia
white lesion, patch or plaque of the oral mucosa CANNOT be removed by rubbing the mucosal surface benign, 6% dysplastic or early SCC
80
Leukoplakia - causes and location
to chronic irritation (dentures, smokeless tobacco, lichen planus) lateral mouth, inside lip, lateral tongue
81
Leukoplakia - Dx
Bx to rule out cancer (esp. if enlarging, indurated or ulcerative and extending deeper than submucosa)
82
Leukoplakia - DDx
thrush, lichen planus
83
Leukoplakia - Tx
nothing specific
84
Erythroplakia
Red, mucosal plaques definite erythematous component (unlike leukoplakia - similar tho)
85
Erythroplakia - common in and locations
older men lateral tongue, floor of mouth, soft palate, alveolar ridge
86
Erythroplakia - Dx
Bx - 90% malignant (look for erythroplakia in leukoplakia!)
87
Erythroplakia - Tx
nothing specific
88
Oral lichen planus
Chronic inflammatory autoimmune disease
89
Oral lichen planus - appearance
Lacy/Reticular leukoplakia , may be erosive can vary significantly May mimic other diseases (candidiasis, hyperkeratosis, SCC)
90
Oral lichen planus - DX
bx required to prove dx and rule out other dz
91
Oral lichen planus - TX
manage pain and discomfort topical CS
92
Oral and Oropharyngeal Cancer
Any cancer arising within the oral or oropharyngeal cavity
93
Oral cancers: 90%
90% Squamous Cell Carcinoma
94
Oropharyngeal: significant association with
HPV
95
Oral and Oropharyngeal Cancer Major risk factors
Increased age (esp >45) Tobacco use (chewing and smoking) Alcohol use
96
Oral and Oropharyngeal Cancer - who needs bx
Any area of erythroplakia Any enlarging area of leukoplakia Any lesion that has submucosal depth on palpation Ulcerative lesions
97
Oral and Oropharyngeal Cancer - locations
Lateral tongue Floor of the mouth Gingiva Buccal area Palate Tonsillar fossa + palpation of the neck for enlarged lymph nodes
98
Oral cancer Early lesions appear as... More advanced lesions -
as leukoplakia or erythroplakia - larger, with invasion into the tongue (may be palpable or ulceration)
99
Oral cancer - s/s and location
early - painless and subtle physical changes majority - ant 2/3 of tongue and floor of mouth
100
Oral cancer - tx
early detection key! <4mm = less likely metatasize <2cm = local resection Larger lesions = combo resection, neck dissection, and external beam radiation
101
Oral cancer - prognosis
dependent on stage at dx stage 1 about 90%, higher stages about 60%
102
Oropharyngeal Cancer arising in the ...
soft palate, tonsils, base of tongue, pharyngeal wall and vallecular
103
Oropharyngeal Cancer - MC
SCC and presents later than oral cavity CA
104
Oropharyngeal Cancer - risk factors
similar to oral CA
105
Oropharyngeal Cancer - signficant assoc. w/
HPV infxn (70%) - respond well to RADIATION
106
Oropharyngeal Cancer - S/s
unilateral throat masses (1 large tonsil = abnormal) painful swallowing weight loss ipsilateral cervical lymphadenopathy persist. sore throat, diffi. swallowing, voice changes, cough, lump in throat/neck
107
Oropharyngeal Cancer - dx
bx eval for metastases
108
Oropharyngeal Cancer - Tx
surgical resection tumors + external beam rad +/- chemo
109
Sialadenitis
Acute infection of the salivary gland MC parotid or submandibular Retrograde bacterial contamination from the oral cavity
110
Sialadenitis - process
Ductal obstruction -> mucous plug -> salivary stasis -> secondary infection
111
Sialadenitis - MC bacterial cause
S. aureus
112
Sialadenitis - other causes
strep species, H. influ
113
Sialadenitis - s/s
Acute swelling of the gland Bad taste Fever Dry mouth Increased pain and swelling with meals due to duct obstruction Tenderness and erythema of the duct opening
114
Sialadenitis - Tx
IV/oral abx Hydration warm compresses Sialagogues (lemon drops, sour candy or Pilocarpine) Gland massage imaging and refer if no improvement I&D?
115
Sialadenitis - complications
Abscess Stricture Stone Tumor Suppurative sialadenitis
116
Parotitis
Acute infection of the parotid gland
117
Parotitis - s/s and dx
neck swelling - parotid tail rides low look inside mouth and press - purulence draining from parotid duct rule out mumps in kids w/ parotid/facial swelling
118
Parotitis - tx
typically non-surgical
119
Acute Suppurative Sialadenitis
Typically one major salivary gland is affected Usually the parotid
120
Acute Suppurative Sialadenitis - s/s
Pain and swelling of the affected gland Induration Tenderness Massage of the gland may express pus from intraoral orifice
121
Acute Suppurative Sialadenitis - Tx
warm compresses sialogagues oral hygiene oral abx (augmentin)
122
Sialolithiasis
Formation of a stone in the salivary ductal system Most common: Wharton duct- submandibular gland
123
Sialolithiasis - s/s
Large, radiopaque Less common- Stensen duct- parotid gland Smaller, radiolucent post-prandial pain and local swelling may have recent history of sialadenitis
124
Sialolithiasis - dx
NCCT if stone not palpable (imaging of choice)
125
Sialolithiasis - Tx
Hydration Warm compresses Sialogogues Analgesics Refer to ENT for removal or if severe symptoms and not responding
126
Chronic Salivary Disorders
Inflammatory or infiltrative Unilateral or bilateral parotid gland enlargement Lymphoephithelial/granulomatous diseases: - Sjogren’s - Sarcoidosis
127
Chronic Salivary Disorders Metabolic disorders
Alcoholism DM Vitamin def.
128
Chronic Salivary Disorders Certain drugs
Thioureas, iodine, cholinergics Any medication that stimulates salivary flow and causes more viscous saliva
129
Salivary Gland Tumors
MC site : parotid gland (80%) benign 80% - MC tumor = pleomorphic adenoma (but potential to become malign.) tumors of submandibular 40-50% malig
130
Salivary Gland Tumors MC malignant tumors
Mucoepidermoid carcinoma Adenoid cystic carcinoma
131
Salivary Gland Tumors S/S
slow growing painless masses facial n. involve strongly corresponds to malign
132
Salivary Gland Tumors - Dx
fine needle aspiration (FNA) vs. excision FNA is old or too unhealthy for surgery
133
Salivary Gland Tumors - Tx
refer ENT
134
Salivary Gland Tumors - prog
5 yr survival rate about 72% varies on stage and type
135
Xerostomia
AKA "dry mouth" Salivary glands do not make enough saliva to lubricate the mouth
136
Xerostomia - causes
Med SE: Antihistamines, antidepressants, antipsychotics, parkinson’s disease medications, diuretics, neuroleptics, anti-cholinergic medications untreated depression Radiation of head or neck
137
Xerostomia - tx
Sialogogues Freq. sips water Ice chips, Saliva substitutes- sprays (biotene) Change/adj meds oral pilocarpine cavity prevention - overnight fluoride trays
138
Xerostomia - complications
dental caries parotid gland enlargement fissuring lips oral candidiasis halitosis ulcers/inflamm of tongue
139
Torus Palatinus
Bony overgrowth (exostosis) -midline of the hard palate very common - develops during childhood and enlarges over time slowly
140
Torus Palatinus - appearance
a bony, hard, nodular, lobular, or spindle-shaped mass covered with normal mucosa
141
Torus Palatinus - s/s and dx
gen. asymp. rapid change/growing, not on midline, or atypical appearance = refer for imaging/bx
142
Torus Palatinus - tx
surgical removal (symptomatic or protruding fit of dental devices)
143
Torus mandibularis (mandibular exostoses)
lingual, More common than torus palatinus