Diseases Of The Aorta / Cardiac Patho Test 2/2 Flashcards

(70 cards)

0
Q

The descending aorta becomes fixed to the thorax by the intercostal arteries, LSCA, and _____?

A

Ligamentum arteriosum

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1
Q

The ascending aorta and arch are:

A

Mobile

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2
Q

At what point does the descending aorta become fixed to the thorax?

A

Aortic Isthmus

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3
Q

Recite the regions of the aorta starting from the valve?

A

Ascending Aorta
Transverse Arch
Descending Aorta
Abdominal Aorta

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4
Q

Weakening of an artery involving all three layers of the vessel is called what?

A

Localized Dilation

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5
Q

Aortic aneurysm that represents 3/4 of atherosclerotic aneurysms?

Where or what level do they occur?

A

Abdominal

Between the renal arteries and the bifurcation.

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6
Q

Thoracic dilation can occur anywhere along the thoracic aorta, what is the most common site ?

A

Arch and descending aorta

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7
Q

Perianeurysmal fibrosis (10%) May cause what?

A

Urethral obstruction

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8
Q

90% of abdominal aortic aneurysms are ?

A

Infrarenal

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9
Q

Abdominal aortic aneurysm statistics?

A

Focal widening >3 cm
> 60 yrs
M:F = 5:1

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10
Q

What is one major Abdominal aortic aneurysm complication?

A

25% rupture into the left retroperitoneum, GI tract, IVC.

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11
Q

What are 3 other Abdominal aortic aneurysm complications?

A

Peripheral embolization
Infection
Spontaneous occlusion of the Aorta

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12
Q

What is the normal size of a thoracic aortic aneurysm and wt what point does it tend to rupture?

A

Normal size = 4-5 cm

Rupture at = 10 cm

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13
Q

Statistics of thoracic aortic aneurysms?

A

Mean age = 65 yrs

M:F = 3:1

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14
Q

thoracic aortic aneurysm are associated with ?

A

HTN
CAD
AAA

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15
Q

Symptoms of a thoracic aortic aneurysm ?

A
Subsepternal, back, and shoulder pain experienced by 25%. 
SVC syndrome 
Dysphagia 
Stridor 
Dyspnea 
Hoarseness
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16
Q

What is the gold standard for evaluation of aneurysm?

A

Angiography

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17
Q

Etiology of descending aortic aneurysms?

A

80% atherosclerotic

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18
Q

Percentage of descending aortic aneurysms do to post traumatic circumstances ?

A

15%

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19
Q

CHDs that can lead to descending aortic aneurysms?

A

2% post coarctation, & ductus diverticulum

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20
Q

Syphilis can lead to what type of aneurysms?

A

Ascending aortic aneurysms
And
Arch aneurysms

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21
Q

3 conditions that can lead to arteritis?

A

Takayasu
Giant cell
Relapsing polychondritis

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22
Q

3 conditions that can lead to cystic medial necrosis ?

A

Marfan
Ehlers-Dantos
Annuloaortic ectasia

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23
Q

Aneurysms arise in areas of dense ?

A

Atherosclerosis

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24
Atherosclerosis erodes into the aortic wall and destroys ?
Medial elements
25
During atherosclerotic aortic aneurysms the aorta widens and then what happens?
Tension increases, which accelerates the process.
26
Blunt trauma to the chest AKA
De-acceleration injury
27
Rupture of the Aorta occurs in ____ of all fatal auto accidents?
1/6
28
What is the most common site of aortic rupture during fatal car accidents ?
Ligamentum Arteriosum
29
What does syphilitic heart disease primarily effect?
Media of the Thoracic Aorta. AI is common
30
Etiology of Mycotic Aneurysm of the Aorta?
IV drug use Bacterial endocarditis 12% Immunocompromise S/P AV surgery, CABG
31
Organisms that cause Mycotic Aneurysm of the Aorta?
S. Aureus (53%) Salmonella (33-50%) Streptococcus
32
Sites of Mycotic Aneurysm of the Aorta?
Ascending aorta > Visceral artery > intracranial Artery > upper/lower extremity arteries
33
Inflation of the aorta ?
Takayasu Arteritis AKA Giant cell Arteritis Aortic arch syndrome Pulseless disease
34
thickening of wall of aortic arch + thoracic aorta. chronic obliterative arteritis of + carotid arteries subclavian. diminished pulses in upper extremities may ==>
rib notching
35
Cystic Medial Necrosis of the Aorta Seen in
elastic arteries
36
Cystic Medial Necrosis of the Aorta Characterized histologically by
deposits of amorphous basophilic accumulations “Microcysts” | within the media
37
“Microcysts” can coalesce and interrupt the elastic fibers causing
weakening.
38
Marfan’s Syndrome
Connective-tissue disorder: autosomal dominant, | 15% sporadic
39
Marfan’s Syndrome
* aortic aneurysm (mostly ascending) * dilatation of aortic sinuses * aortic dissection * coarctation * tall stature, long limbs * arachnodactyly * lax joints * scoliosis (60%) / kyphosis / pectus * dural ectasia * lens subluxation
40
Aortic dissection Caused by
sudden tear in intima allowing for a column of blood to enter the Ao wall
41
What is a prerequisite for Aortic dissection?
Degeneration of media
42
Aortic dissection can be described as ?
Cystic medial necrosis-deterioration of collagen and elastic tissues
43
Aortic dissection is common in what medical syndrome?
Marfan's syndrome
44
DeBakey Type I Aortic dissection
ascending Ao and beyond
45
DeBakey Type II Aortic dissection
confined to ascending Ao
46
DeBakey Type IIIa Aortic dissection
descending, confined to thorax
47
DeBakey Type IIIb Aortic dissection
descending, extends beyond diaphram
48
Shumway/Stanford Type A
origin in ascending
49
Shumway/Stanford Type B
origin in descending
50
what are the three main surgical options for descending aortic lesions?
Clamp & run Shunt Left heart bypass
51
Explain the shunt surgical option for descending aortic lesions?
a Gott Shunt is placed from above the aneursym and connected beyond the distal clamp. Simple but one can not easily control flow through shunt
52
Type III Descending Aortic Lesion requires Clamping the aorta to correct the lesion, which then results in hypoxia and ischemia to the lower body. What are three complication s that we can face?
Paraplegia Renal failure Ischemia-reperfusion injury
53
What is Left Heart Bypass?
Taking blood from the LA and returning it through the femoral artery. Bypasses the LV.
54
Is an oxygenator required for Left Heart Bypass ?
No, blood in LA is fully oxygenated
55
When would we need to use left heart bypass?
Type III Aortic Aneurysms To assist/support a failing ventricle LVAD, RVAD, BiVAD
56
Perfusion Parameters for left heart bypass?
Pump Flows can be 1/2 what you would flow with full CPB. Be careful to balance the upper body and lower body perfusion! Don’t sacrifice good cerebral perfusion!
57
Cardiac index for lowerbody perfusion?
1.0
58
Treatment for an Aortic disses ton Type A ?
Ascending dissection requires surgery
59
Treatment for an Aortic disses ton Type B ?
Descending dissection can be medically managed by controlling BP and preventing extension.
60
What are the 2 components of the surgical adhesive?
Bovine Serum Albumin | Glutaraldehyde
61
Bioglue curing time?
Starts 20-30seconds | Finished in 3 minutes
62
Aortic dissection outcomes with medical treatment ?
80% 1 year survival | 50% 3-5 year survival
63
Operational mortality for ascending ?
5 -10%
64
Operational mortality for descending ?
10%
65
Operational mortality for arch ?
10 -25%
66
Operational 10yr survival for aortic dissection?
46%
67
Percentage risk for a | re-dissection?
10%
68
Remember: you are dealing with 2 circuits that share 1 source:
The upper body is perfused by the LV ejections. | The lower body is being perfused by the pump.
69
If you are measuring arterial pressures in the upper body then you have
a inverse relationship between pressure and pump flow