Diseases with STAGES Flashcards Preview

RENAL Pathology > Diseases with STAGES > Flashcards

Flashcards in Diseases with STAGES Deck (35):
1

↑GFR due to constriction of the EFFERENT arteriole

Stage 1: Hyperfunction/hypertrophy (diabetic)

2

thickening of BM and expansion of mesangium; normal GFR

Stage 2: Silent stage (diabetic)

3

MICROalbuminuria;
GFR dec.

Stage 3: Incipient stage (diabetic)

4

MACROalbuminuria, decreased GFR and hypertension

Stage 4: Overt diabetic nephropathy (diabetic)

5

ESRD
GFR

Stage 5: Uremic (diabetic)

6

subepithelial dense deposits w/o adjacent projections of GBM material.

Stage 1 membranous

7

projections of GBM material around these dense deposits

Stage 2 membranous

8

enclosure of the dense deposits within the GBM material

Stage 3 membranous

9

rarefaction of the deposits within a thickened GBM.

Stage 4 membranous

10

Immediate rise in BP is due to hyperreninemeia

STAGE 1:Renovascular HTN:

11

Stenotic kidney --> ↑renin and retains sodium and water
Contralateral non-stenotic kidney --> ↓ renin production

STAGE 2:Renovascular HTN:

12

HTN leads to renal hypoperfusion of BOTH KIDNEYS

STAGE 3:Renovascular HTN:

13

Glomerular hyperfiltration

Stage 1 diabetic

14

Thickened BM; Expanded mesagium

Stage 2: Silent Stage; diabetic

15

Type 1 diabetes INC. BP; Type II normal

Stage 3 Insipient Stage

16

Type I and Type II normal BP

Stage 1 and 2

17

Type i and II HTN

Stage 4 and 5

18

Stage 1 through 4 GFR in diabetic Nephropathy

Stage I INC.
II--> NORMAL
III--> GFR begins to fall
IV--> GFR DEC more
V--> 0-10 (esrd)

19

Alport vs benign familial hematuria EM

Alport--> irregular thickening of basement membrane; foci of rarefaction;
Bfh--> diffuse thinning of BM

20

AKI
Slight oliguria with INC. in BUN

Initiation phase AKI

21

AKI
Inc. Oliguria; rising BUN;
HYPERkalemia
Metabolic acidosis

Maintenance phase

22

AKI
Polyuria
HYPOkalemia

Recovery phase AKI

23

Chronic renal:
GFR 50%; normal BUN:Cr; asymptomatic

Stage I: Dim. Renal reserve

24

Chronic Renal:
GFR 20-50%
Polyuria and nocturia

Stage II: Renal insuff

25

Chronic renal:
GFR

Stage III: Chronic Renal failure

26

Chronic renal:
GFR

Stage 4: ESRD

27

renal osteodystrophy

Chronic renal faiulre

28

MAD HUNGER

Metabolic Acidosis
Dyslipidemia
HYPERkalemia
Uremia
Na+/H2O retention--> edema
Growth retardation
Erythropoietin failure (anemia)
Renal osteodystrophy (hypocalcemia)

29

HYPERkalemia

Chronic renal failure
AKI

30

Metabolic acidosis

AKI
Chronic Renal failure

31

S/s of uremia

Pericarditis;
Frost on SKIN
Coagulopathy
Asterixis

32

Frost on SKIN

uremia; chronic kidney injury

33

Pericarditis;

uremia; Stage IV chronic renal failure

34

See uremia in what stage of chronic renal failure:

Last stage; stage IV--> ESRD

35

Sheets of undifferentiated cells with hemorrhage and necrosis

Embryonal carcinoma