Diuretics Flashcards
What is the Loop Diuretic Conversion?
Furosemide 20 IV = Furosemide 40 PO = Toresmide 20 IV/PO = Bumetanide 1 IV/PO
What are the indications for Diuretics?
HTN and Edema
What drugs are effective for HTN and Edema?
HTN: Thiazides/Aldosterone
Edema: Loop
Chlorthalidone has the longest half life but in return has what?
Most electrolyte wasting
When is HCTZ less effective?
CrCl <30
Which Aldosterone Antagonist is more selective for mineralocorticoid receptors?
Eplereone = less gynecomastia
What are the Loop Diuretics?
Furosemide, Torsemide, and Bumetanide
What are the Thiazides/Like Diuretics?
HCTZ, Indapamide, Metolazone, and Chlorthalidone
What are the Potassium-Sparing Diuretics?
Triamterene, Spironolactone, and Eplerenone
When should you check serum potassium for Potassium-Sparing Diuretics?
Within 3 days of starting then 1 weeks, and then monthly for 3 months
What is the indication of Lasix?
Edema, HTN, and Ascites
hat is the indication of Bumex?
Edema
What is Dyazide?
Hydrochlorothiazide 25 mg/triamterene 37.5 mg: CAPSULES
What is Maxzide?
Hydrochlorothiazide 50 mg/triamterene 75 mg: TABLET
What is the indication of Demadex?
Edema and HTN
What is the indication of HCTZ?
Edema and HTN
What is the indication for Indapamide?
Edema and HTN
What is the indication of Chlorthalidone and its half life?
Edema and HTN
40-60 hrs
What is the indication of Metolazaone?
Edema
When Metolazone is combined with Loops what is the precaution?
Enhanced diuresis, close monitoring needed
What is the indication of Aldactone?
HTN, HFrEF, Primary Aldosteronism, Cirrhosis
What DDIs are there with Aldactone?
ACE, Potassium Sparing Meds, and Potassium Supplements
What are the CIs of Aldactone?
Anuria/Renal Insufficiency, and Hyperkalemia
What is the indication of Inspra?
HF post MI and HTN
