DM Foot problems Flashcards

(47 cards)

1
Q

What are the three major complications that arise from DM?

A
  • Peripheral neuropathy
  • Autonomic Neuropathy
  • PVD
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2
Q

What are the arteries that are classically associated with PVD?

A

Tibial

Peroneal (fibular)

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3
Q

What are the three major contributing factors of PVD in DM?

A
  • Smoking
  • HTN
  • Hyperlipidema
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4
Q

What happens to bone with autonomic dysfunction of the foot?

A

Dilation of vessels, causing increased bone resorption

charcot foot

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5
Q

What happens to the skin of the foot with autonomic dysfunction of the foot?

A

Dry, cracked skin

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6
Q

What are the immune consequences of PVD?

A

Impaired wound healing

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7
Q

What are the components of metabolic syndrome?

A
  1. Hyperinsulinemia
  2. Hypertriglyceridemia
  3. HTN
  4. Central obesity
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8
Q

What are the ssx of PVD?

A
  • Atrophic skin
  • Rest pain
  • Claudication
  • Pallor on elevation
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9
Q

What happens to the aorta and medium sized vessels with PVD?

A

Accelerated atherosclerosis

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10
Q

What are the major PE findings of PVD?

A
  • Diminished pulses
  • Cap refill time
  • Skin atrophy
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11
Q

What is the inexpensive test that can be used to evaluate for PVD?

A

Ankle brachial index

Greater than 0.50

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12
Q

What is the minimum value of the ABI and transcutaneous oxygen that is needed for healing in the foot?

A

More than 0.5

More than 30 mmHg

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13
Q

What is a normal ankle brachial index? Moderate obstruction?

A

Above 0.9

Moderate = 0.5-0.8

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14
Q

At what level of obstruction does loss of the arterial rebound with occur? What about loss of the reversal of blood flow

A

Mild obstruction

Moderate obstruction

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15
Q

What can cause an inaccurate ABI? Why?

A

Calcified vessels will lower the ratio, since they will not compress as readily

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16
Q

What happen to the waveform of the doppler US as you progress from normal to severe obstruction?

A
Normal = triphasic
Mild = biphasic
Moderate = monophasic
Severe = loss of peaks
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17
Q

What is transcutaneous oxygen pressure measurement?

A

O2 levels in the arteries through the skin

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18
Q

Why may someone with a poor ABI have a normal transcutaneous oxygen pressure?

A

Collateral circulation

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19
Q

What are the invasive vascular exam that may be performed to assess for arterial oxygen? (3)

A

Arteriography
MRA
DSA

20
Q

What are the causes of the increased ulceration risk with peripheral neuropathy, beside the loss of sensation and increased blood flow?

A

More pressure on the toes and bony prominences

21
Q

What is “neuro-traumatic” theory of Charcot foot osteoarthropathy?

A

Exaggerated overuse injury coupled with loss of protective sensation

Allows for continued tissue destruction in

22
Q

What is “neurovascular” theory of Charcot foot osteoarthropathy?

A

AV shunting leads to excessive bone resorption, contributing to fractures

23
Q

What is stage 1 Charcot neuropathy?

A

The acute destructive phase, characterized by inflammation, joint effusion, and degradation of bone

24
Q

What is stage 2 Charcot neuropathy?

A

Coalescence phase:

-Further bone/cartilage destruction, but initiation of sclerosis where cartilage has degraded, and fusion of bone fragments

25
What is stage 3 Charcot neuropathy?
Reconstruction phase: - Remodeling of joint surfaces - Sclerosis
26
What is the treatment for the acute stage of Charcot foot?
- Reduce weight bearing - Cast immobilization - Drugs to inhibit bone resorption - Manage ulcers
27
What is the major issue with immobilization of one foot for charcot?
Will favor the other foot, causing Charcot on the other
28
How do you follow Charcot?
Weekly foot x-rays
29
When is surgery for Charcot indicated?
If causing pressure ulcers d/t bone remodeling
30
What happens to the bones with Charcot foot?
"Rocker-bottom" foot d/t loss of midfoot
31
What are the four major types of ulcerations?
Arterial Venous Neuropathic Pressure
32
What are the molecular stages of chronic wound healing?
Constant inflammatory cytokines increases proteases and MMPs, and a loss of GFs and TIMPs
33
What is grade 0 Wagner's foot?
No evidence of ulcer or infx
34
What is grade 1 Wagner's foot?
Superficial ulcers
35
What is grade 2 Wagner's foot?
Ulcers that have not yet penetrated to the bone or fascial plane
36
What is grade 3 Wagner's foot?
Ulcers extend to bone, or have invaded fascial plane
37
What is grade 4 Wagner's foot?
Feet have gangrene of the *forefoot*
38
What is grade 5 Wagner's foot?
Gangrene of the entire foot that will likely require amputation
39
What are the general principles of ulcer wound management (3)
- Increase vascular supply - Debride/wound management - Offload
40
What are the most common infections seen in DM Pts?
Bacterial and fungal skin infx
41
How do you collect a good culture of the foot?
Deep swab and collect purulence
42
What is the definitive diagnostic modality for osteomyelitis?
Bone biopsy
43
What are Tc-99m scans used for?
Collects on osteoapatite very sensitive, but not specific
44
What can indium scans detect?
WBCs with: Acute osteomyelitis Acute cellulitis
45
What can ceretec scans detect?
WBCs with: | Acute osteomyelitis
46
What can Tc-99 scan detect? (4)
- Acute/inactive osteomyelitis - Acute cellulitis - Charcot joint
47
Why is it that the indium scan no detect inactive chronic osteomyelitis?
No WBCs present