DNA Flashcards

(49 cards)

1
Q

DNA

A

Long chains of nucleotides
Made of phosphates,sugar,bases
Two chains run antiparallel in opposite directions
5’ sugar has a phosphate

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2
Q

Double helix, t pairs with a c pairs with g

A

DNA

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3
Q

DNA replication

A

Makes more dna
Occurs in nucleus
Occurs during a phase of interphase before mitosis and meiosis

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4
Q

DNA replication is semi conservative

A

One old stand one new strand

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5
Q

many enzymes work together to copy dna

A

DNA replication

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6
Q

Helicase

A

Unwinds dna(separates) by breaking hydrogen bonds

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6
Q

Topoisomerase

A

(Person standing on black lines)
Holds dna so it doesn’t retwist

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7
Q

Primase

A

Adds rna primer to start replication ,shows dna polymerase where to attach

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8
Q

DNA polymerase

A

Removes primer and adds can nucleotides in 5 to 3 direction also proofreads to catch errors and mutations

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9
Q

Leading strand

A

Made continuously, dna polymerase moves toward helicase as strands are separating

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10
Q

Lagging strand

A

Made in pieces( Okazaki fragments) bc dna polymerase can only add nucleoTides to growing 3’ end

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11
Q

Ligase

A

Seals together fragments on lagging strand

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12
Q

Uses dna to make mRNA so that the instructions in dna can be brought to the Protien building machinery outside the nucleus, occurs in nucleus of eukaryotic cells

A

Transcription

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13
Q

RNA

A

Single stranded, contains U uracil can be inside or outside nucleus

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14
Q

Helicase

A

Separates 2 strands of dna by breaking hydrogen bonds , uses in transcription

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15
Q

RNA polymerase

A

Build s mRNA using dna template used in transcription

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16
Q

Gene

A

Piece of dna that is use to make mRNA in a protiem

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17
Q

Promoter

A

Start of gene tells rna polymerase where to start

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18
Q

Terminator

A

End of a gene, tells rna polymerase where to stop

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19
Q

mRNA editing

A

Modifications to mRNA after transcription, occurs in nucleus, before the mRNA enters cytoplasm

20
Q

Spliceosome

A

Cuts out non coding pieces of mRNA called introns

21
Q

Introns

A

Non coding pieces of mRNA

22
Q

Exons

A

Coding pieces of mRNA

23
Q

Alternate splicing

A

Different mRNA pieces are considered introns, so multiple different protiems can be made using same gene

24
Two types of mRNA editing
Poly tail A: lots of A added, tells cell this is useful mRNA, not to destroy 5’ cap: modified guanine tells cell the mRNA is ready to leave the nucleus to make a Protien
25
Translation
Uses mRNA to make a Protien
26
Protiens
Chains of amino acids
27
Amino acids
Pieces of a Protien
28
Codon
A set of 3 mRNA bases that codes for an amino acid
29
Ribosome
translation occurs
30
tRNA
Transfer amino acid to ribosome
31
Point mutation
single base incorrect ( substitution)
32
Frameshift mutation
Bases added or deleted
33
How does rna polymerase differ from dna polymersse
Rna polymerase can begin adding mRNA nucleotides but dna polymerase requires primate to begin dna synthesis
34
Each stand of the original double stranded dna molecule serves as a template for newly constructed completary strand
Characteristic of dna replication
35
When dna is produced from a dna template strand
Transcription
36
What would happen if ribosome was disrupted
The cell would not be able to make Protiens
37
Messing up dna sequence would result in
Change in codons a Causing different amino acids to be placed in the Protien
38
What happens when a tRNA molecule delivers an amino acid to the ribosome
The amino acid is bonded to another amino acid to create a growing polypeptide
39
30 nucleotides results in how many amino acids in a protien
10
40
RNA contains
Uracil
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