Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

OBGYN pharmacology > DOC/ indications > Flashcards

DOC/ indications Flashcards

(63 cards)

Start Studying
1
Q

mag sulfate

A

delay labor- relax uterus

preeclampsia

eclampsia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

clomiphene

A

(anti-estrogen)

DOC for infertility in women

(stimulates LH and FSH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

ergonovine maleate

methylergonovine maleate

A

(ergots)

prevent hemorrhage after delivery or suction abortion

(by causing contractions)

not first line (OT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

leuprolide

goserelin

A

(long acting GnRH agonists)

precocious puberty

prostate CA

endometriosis

(can also be used in ART to suppress LH and FSH

but GnRH antagonists preferred)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

“gliptins”

A

(DPP-4 inhibitors)

medium A1C decrease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

raloxifene

A

(anti-estrogen)

post menopausal osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PTH effects

A

increases serum calcium

by getting osteoblasts to release RANK-L (osteoclastic)

increases renal reabsorption

increases GI absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

acarbose

miglitol

A

T1DM and T2DM

moderate A1C decrease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

colesevelam

A

small decrease in A1C

decreases LDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HMG (FSH analog)

HCG (LH analog)

A

infertility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

tamoxifen

A

(anti-estrogen)

DOC for estrogen dependent breast CA

pre and post menopause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

indomethacin

A

(NSAID)

delay labor- relax uterus

by reducing prostaglandins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

nitroglycerin

A

in emergency to delay labor- relax uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

calcitonin effects

A

decreases serum calcium

stimulated by estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

“dronates”

A

(bisphosphonates)

DOC for osteoporosis

in men and postmenopausal women

pagets disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

metformin benefits

A

1st line- big decrease in A1C

reduces glucose to euglycemic state

good for heart- decreases MIs

does not increase weight

decreases mortality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

pramlintide

A

(amylin like peptide)

used in T1DM and T2DM

small decrease in A1C

weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

testosterone

methyltestosterone

A

M- testicular deficiency

F- female hypopituitaryism (treated w/ both estrogens and androgens)

everyone- debilitated people (burns, preemies, post op pts)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

vit D effects

A

increases blood calcium

by getting osteoblasts to release RANK-L (osteoclastic)

increases renal reabsorption

increases GI absorption

  • works in conjunction w/ PTH*
  • stimulates collagen synthesis in osteoblasts*
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

tolbutamide, chlorpropamide, tolazamide

glyburide, glimepride, glipizide

A

(sulfonylurea)

big A1C decrease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

drospirenone/ethinyl estradiol

A

combo oral contraceptive that

reduces water retention

reduces PMDD sxs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

nifedipine

A

(CCB)

delay labor- relax uterus

starting to be 1st line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

calcium

A

alone will not prevent or tx osteoporosis

needed for other tx to work though

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

cetrorelix

ganirelix

A

(GnRH antagonists)

ART (suppresses LH and FSH)

endometriosis

prostate CA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
carboprost tromethamine
(prostaglandin) abortion- 2nd trimester
26
calcitonin
prevents vertebral compression fractures
27
propylthiouracil
(thioamide derivative) **for pregnant women with hyperthyroidism, Graves, toxic nodular goiter** (tachycardia, wide pulse pressure, sensitivity to heat, tremor, fatigue, weight loss, diarrhea, increased sensitivity to adrenergic stimulation)
28
radioactive iodine 131
**DOC for toxic nodular goiter** LD for hyperthyroid diagnosis HD for thryoid destruction (ablation) hyperthyroid pts with heart dz that cannot tolerate sx
29
danazol
(weak progestin + androgen) endometriosis
30
repaglinide nateglinide
(meglitinide) if you want to give a sulfonylurea but can't because of sulfa allergy
31
liothyronine sodium
(T3) **myxedema coma or severe hypotension** (poorly responsive pt w/ thyroidectomy scar)
32
iodide
**used prior to thyroidectomy** (it decreases gland vascularity) to prevent uptake of radioactive iodine hyperthyroidism- short term effect (tachycardia, wide pulse pressure, sensitivity to heat, tremor, fatigue, weight loss, diarrhea, increased sensitivity to adrenergic stimulation)
33
**exemestane** anastrozole letrozole
(aromatase inhibitor) **DOC- POST menopausal refractory breast CA**
34
mifepristone
(anti-progestin, also antagonizes glucocorticoid receptors) abortion often used in combo w/ PG (RU-486)
35
what do you give to girls who don't go through puberty
HRT estrogens + progesterone (combo to reduce ovarian hyperplasia) use LD
36
"gliflozins"
(SGLT-2 inhibitors) medium A1C effect good for heart- decreases MI weight loss
37
what do you give for: vasomotor problems: HA, hot flashes GU: dryness, painful sex osteoporosis heart disease
HRT **estrogens** + progesterone (combo to reduce ovarian hyperplasia) use LD **ONLY BENEFICIAL FOR 1ST 5-10 YEARS OF MENOPAUSE** raloxifene
38
male infertility issues due to pituitary prob or hypothalamic hypogonadism (ART)
**1st HCG- LH- given for up to a year** (stimulates testosterone) **2nd HMG- FSH- added for months** (stimulates spermatogenesis)
39
teriparatide abaloparatide rhPTH
(recombinant PTH) **osteoporosis** not DOC but the **only anabolic menopausal tx**
40
what do you give to a pt who wants a "bioidentical birth control"
natazia
41
pioglitazone rosiglitazone
(thiazolidinones) big decrease in A1C SPECIFICALLY TARGETS INSULIN RESISTANCE
42
levothyroxine sodium
(T4) **hypothyroidism** (slow metabolic rate, hypothermia, sensitive to cold, fatigue, bradycardia, thick skin, low BP)
43
vit D
prophylaxis of osteomalacia
44
estrogen dependent breast CA
tamoxifen
45
bromocriptine mesylate
(dopamine agonist) small decrease in A1C reduces FA and TG levels good for the heart
46
propanolol
decrease hyperthyroidism sxs (tachycardia, wide pulse pressure, sensitivity to heat, tremor, fatigue, weight loss, diarrhea, increased sensitivity to adrenergic stimulation)
47
"glutides" and exenatide benefits
(GLP-1 agonists) big decrease in A1C good for heart- decreases MI weight loss
48
finasteride dutasteride
(5 alpha reductase inhibitors) benign prostatic hyperplasia male pattern baldness
49
female infertility issues | (ART)
in sequence: **1st- HMG- for 9-12 days** (develops ovarian follicles) **2nd- HCG- 1 dose** (helps to synthesize progesterone in corpus luteum)
50
tranexamic acid
(anti-fibrinolytic) reduced postpartum hemorrhage death
51
flutamide bicalutamide nilutamide
(androgen receptor antagonist) prostate CA also when you initiate long acting GnRH agonists to suppress the initial surge of androgens
52
estradiol estrogens
oral contracetives hormone replacement therapy primary hypogonadism (to stimulate puberty) prostate CA
53
19-nortesterone progesterone, medroxyprogesterone, megestrol acetate
contraception +/- estrogen decrease endometrial hyperplasia in HRT prophylactically to maintain pregnancy (and delay early contractions in at risk pregnancy)
54
methimazole
(thioamide derivatives) **DOC for hyperthyroidism and Graves** also for toxic nodular goiter (tachycardia, wide pulse pressure, sensitivity to heat, tremor, fatigue, weight loss, diarrhea, increased sensitivity to adrenergic stimulation)
55
denosumab
osteoporosis in postmenopausal women and men at high risk of fractures in review she said it was also good for osteoporosis prevention in CA pts
56
dinoprostone
(prostaglandin) abortion cervical ripening (gel form)
57
spironolactactone
hirsutism precocious puberty VERY HIGH DOSE
58
oxytocin
**DOC to induce labor** (after massage has been tried) prevent hemorrhage after delivery stimulate milk let down
59
breast CA: 1st, 2nd, 3rd line
DOC- tamoxifen 2- exemastane, anastrozole, letrozole (but not in premenopause) 3- fulvestrant
60
DM agents' A1C... high to low effect
high metformin, GLP-1, sulfonylureas, thiazolidinones med DPP-4, SGLT-2 low acarbose, miglitol, bromocriptine, repaglinide, nateglinide, pramlintide
61
order of drugs for postpartum hemorrhage
1- massage 2- OT 3- ergots 4- tranexamic acid (anti-fibrinolytic)
62
drugs for abortion
dinoprostone carboprost tromethamine mifepristone
63
drug for placenta delivery
ergots

OBGYN pharmacology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions