Donor Requirements And Intervals

Question 1

Age

Answer 1

16 years old

Or applicable state law

Question 2

Blood pressure

Answer 2

Systolic: 90-180
Diastolic: 50-100

Question 3

Weight

Answer 3

110 lbs

Question 4

Temperature

Answer 4

< 37.5 C (99.5 F)

Question 5

Pulse

Answer 5

50-100

Question 6

Skin examination

Answer 6

Free of infection, inflammation, and evidence is drug use

Mild skin issues only a problem if they interfere with decontamination process

Question 7

Female Hgb/Hct

Answer 7

12.5 g/dL

>38%

Question 8

Male Hgb/Hct

Answer 8

13.0 g/dL

>39%

Question 9

Hgb/Hct determination method

Answer 9

Anything but earlobe capillary collection

Except for double RBC donation- must be quantitative measurement (no copper sulfate method)

Question 10

Autologous donation criteria

Answer 10

Hgb > 11.0 g/dL
Collection > 72 hrs before surgery/use
Physician order for collection

Question 11

Donation interval:

While blood

Answer 11

8 weeks

Question 12

Donation interval:

2 unit RBC

Answer 12

16 weeks

Question 13

Donation interval:

Infrequent plasmapheresis

Answer 13

4 weeks

Question 14

Donation interval:

Frequent plasmapheresis

Answer 14

2 days (not >2 in 7 days)

Question 15

Donation interval:

Plateletpheresis

Answer 15

2 days for single

7 days for double/triple

Question 16

Donation interval:

Cytapheresis (granulocytes)

Answer 16

2 days (no more than 2 times in 7 days)
Not > 24 in rolling 12 months

Question 17

Volume of blood permitted to be collected

Answer 17

10.5 mL/kg of donor weight

Question 18

Post donation donor care

Answer 18

Local pressure applied to phlebotomy site while arm is elevated until hemostasis is achieved

Donor given post donation instructions and observed for signs of adverse reactions

Question 19

Needle related donor injuries (in order of frequency)

Answer 19

Bruise/hematoma
Local nerve injury
Arterial puncture

Question 20

Systemic donation adverse reactions

Answer 20

Vasovagal
Citrate toxicity
Allergic

Question 21

Minimum platelet count for platelet pheresis donation

Answer 21

150,000

Question 22

Deferral for apheresis platelet donation after whole blood donation

Answer 22

8 weeks

Unless extracorporeal volume of instrument is <100 ml

Question 23

Whole blood units unsuitable for platelet or plasma use (2)

Answer 23

Collection time >15-20 min

Low volume unit

Question 24

Frequent plasma donation donor considerations

Answer 24

No deferral for malaria risk

Serum protein 6-9 g/dL

Electrophoresis every 4 months with normal protein fractionation

Physical exam once a year

Question 25

Maximum plasma loss w/in 12 months | 110-175 lb

Answer 25

12 L

Question 26

Max plasma loss w/in 12 months | >175 lb

Answer 26

14.4 L

Question 27

Therapeutic phlebotomy indications (9)

Answer 27

``` Polycythemia Vera Erythropoietin receptor mutations High oxygen affinity Hb mutations Polycythemia due to high altitude residency Cyanotic congenital heart disease Respiratory disease Erythropoietin producing neoplasms Porphyria cutanea tarda (most common) Hereditary hemochromotosis ```

Question 28

Vasovagal risk factors (5)

Answer 28

``` Young age Low weight First time donation Inattentive phlebotomist Epidemic fainting ```

Question 29

Nerve injury risk factors (3)

Answer 29

Hematoma formation Female Younger than average age Usually presents on day of donation Time is major treatment option

Question 30

Arterial puncture characteristics (4)

Answer 30

Severe or unusual pain Rapid filling of bag Bright red blood Movement of needle with heartbeat

Question 31

Low volume unit collection amount

Answer 31

300-404 ml in a 450ml bag 333-449 ml in a 500ml bag

Question 32

Autologous donation: acute normovolemic hemodilution Replacement fluids and ratio

Answer 32

Crystalloid 3:1 Colloid 1:1

Question 33

Autologous donation: acute normovolemic hemodilution Blood storage

Answer 33

Room temp 8 hrs from start of collection

Question 34

Autologous donation: acute normovolemic hemodilution Infusion order

Answer 34

Infused in reverse order of collection | Lower concentration of RBCs infused first

Question 35

Autologous donation: acute normovolemic hemodilution Collection/labeling

Answer 35

Collected into standard blood bags containing anticoagulant Labeled with patient name, MR #, date and time of collection and ‘for autologous use only’

Question 36

Autologous donation: acute normovolemic hemodilution Patient selection criteria

Answer 36

``` Likelihood of transfusion >10% Preop Hgb >12 g/dL No significant coronary artery, pulmonary, renal, or liver disease No severe hypertension Absence of infection/risk of bacteremia ```

Question 37

Time frame of donor eligibility determination

Answer 37

Must be established on the day before collection 24 hrs to clarify any information in the screening

Question 38

Facilities have how long to notify donors of test results that would defer them from further donation

Answer 38

8 weeks