DRILLS

Question 1

Which of the following compounds is
considered as a Grignard’s Reagent?

A. CH₃CH₂OH
B. CH₃Li
C. CH₃MgCl
D. NaHSO₃

Answer 1

CH₃MgCl

Question 2

Which of the following substrates can be
used to synthesize tertiary alcohol?

A. Formaldehyde
B. Ethanol
C. Propanone
D. Ethane

Answer 2

Propanone

Question 3

What type of mixture is produced when
equimolar concentrations of d-epinephrine
and l-epinephrine are present in solution?

A. Racemic
B. Saturated
C. Unsaturated
D. Optically active

Answer 3

Racemic

Question 4

What is the most stable conformation of
cyclohexane?

A. Staggered
B. Chair
C. Boat
D. Eclipsed

Answer 4

Chair

Question 5

Calcium Disodium Versenate may be used
in the treatment for heavy metal poisoning,
primarily that caused by

A. Mercury
B. Arsenic
C. Gold
D. Lead

Answer 5

Lead

Question 6

The only alkali metal that melts above the
boiling point of water is

A. Lithium
B. Sodium
C. Potassium
D. Rubidium

Answer 6

Lithium

Question 7

Which alkali metal hydroxide has the
highest alkalinity?

A. Lithium hydroxide
B. Sodium hydroxide
C. Potassium hydroxide
D. Cesium hydroxide

Answer 7

Cesium hydroxide

Question 8

All oxides and hydroxides of the coinage
metals are freely basic except for

A. Cu₂O
B. Ag₂O
C. Au₂O
D. NOTA

Answer 8

Au₂O

Question 9

Which of the following functional moieties is considered as a prerequisite for the diuretic activity of Thiazide and Hydrothiazide?

A. Sulfamoyl group in position 3
B. Sulfamoyl group in position 7
C. Methyl group in position 4
D. Phenyl grouping in position 3

Answer 9

Sulfamoyl group in position 7

Question 10

Which of the following compounds is classified as a “thiazide-like diuretic” because its mechanism of action and other pharmacologic properties are similar to thiazides, although its chemical structure does not have the benzothiadiazine-1,1-dioxide nucleus?

A. Chlorthalidone
B. Furosemide
C. Dichlorphenamide
D. Hydrochlorothiazide

Answer 10

Chlorthalidone

Question 11

Which of the following compounds is a
5-sulfamoylanthranilic acid derivative?

A. Furosemide
B. Cocaine
C. Triamterene
D. Sulfadiazine

Answer 11

Furosemide

Question 12

What is the cellular mechanism involved in
the ability of NO to cause vascular smooth
muscle relaxation?

A. Inhibition of adenylyl cyclase
B. Stimulation of PDE-III
C. Stimulation of Guanylyl Cyclase
D. Stimulation of PDE-V

Answer 12

Stimulation of Guanylyl Cyclase

Question 13

What secondary messenger is responsible for the vasodilatory action of drugs like Sildenafil and Nitroglycerin?

A. cAMP
B. cGMP
C. DAG
D. IP₃

Answer 13

cGMP

Question 14

Calcium Disodium Versenate may be used
in the treatment for heavy metal poisoning,
primarily that caused by?

A. Mercury
B. Lead
C. Arsenic
D. Bismuth

Answer 14

Lead

Question 15

The only alkali metal that melts above the
boiling point of water is?

A. Lithium
B. Sodium
C. Potassium
D. Rubidium

Answer 15

Lithium

Question 16

Which alkali metal hydroxide has the
highest alkalinity?

A. Sodium hydroxide
B. Potassium hydroxide
C. Cesium hydroxide
D. Lithium hydroxide

Answer 16

Cesium hydroxide

Question 17

All oxides and hydroxides of the coinage
metals are freely basic except for?

A. Cu₂O
B. Au₂O
C. Ag₂O
D. None of the above

Answer 17

Au₂O

Question 18

Which of the following is known as White
Lotion?

A. Zinc sulfide topical suspension
B. Zinc oxide
C. Zinc sulfate
D. Zinc chloride

Answer 18

A. Zinc sulfide topical suspension

Question 19

Which of the following is a gaseous
element?

A. Xenon
B. Radon
C. Krypton
D. Neon

Answer 19

Krypton

Question 20

What is the main toxic effect of beryllium?

A. Neurotoxicity
B. Hepatotoxicity
C. Pulmonary fibrosis
D. Nephrotoxicity

Answer 20

Pulmonary fibrosis

Question 21

The most toxic metal and has no therapeutic use?

A. Lead
B. Mercury
C. Thallium
D. Arsenic

Answer 21

Thallium

Question 22

What is the main application of calcium
hydroxide?

A. Laxative
B. Antacid
C. Astringent
D. Antiseptic

Answer 22

Antacid

Question 23

Which of the following is an example of an alkaline earth metal?

A. Sodium
B. Magnesium
C. Potassium
D. Lithium

Answer 23

Magnesium

Question 24

Which gas is also known as “laughing gas”?

A. Carbon dioxide
B. Oxygen
C. Nitrous oxide
D. Helium

Answer 24

Nitrous oxide

Question 25

A metal that forms amphoteric hydroxides? A. Sodium B. Aluminum C. Calcium D. Copper

Answer 25

Aluminum

Question 26

The most electronegative element? A. Oxygen B. Fluorine C. Nitrogen D. Chlorine

Answer 26

Fluorine

Question 27

Element that predominates in the plasma and interstitial fluids? A. Potassium B. Magnesium C. Calcium D. Sodium

Answer 27

Sodium

Question 28

The black precipitate produced in Marsh's test is? A. Arsenic B. Lead C. Mercury D. Silver

Answer 28

Arsenic

Question 29

The xanthoproteic test makes use of this acid? A. Sulfuric acid B. Hydrochloric acid C. Acetic acid D. Nitric acid

Answer 29

Nitric acid

Question 30

How many protons and electrons are there in P³⁻? A. 15 protons, 31 electrons B. 31 protons, 15 electrons C. 18 protons, 15 electrons D. 15 protons, 18 electrons

Answer 30

15 protons, 18 electrons

Question 31

In thermodynamics, what is everything external to the system that can exchange energy or matter with it? A. Surrounding B. Universe C. System D. Thermodynamics

Answer 31

Surrounding

Question 32

Zinc + Copper sulfate = Zinc sulfate + Copper A. Combination reaction B. Decomposition reaction C. Single displacement reaction D. Double displacement reaction

Answer 32

Single displacement reaction

Question 33

Which of the following oxides exhibits amphoteric behavior? A. SO₂ B. Al₂O₃ C. Na₂O D. P₂O₅

Answer 33

Al₂O₃

Question 34

The reaction between sodium and ammonia in liquid ammonia results in the formation of: A. Sodium hydroxide B. Sodium amide C. Sodium amide and solvated electrons D. Sodium hydride

Answer 34

Sodium amide and solvated electrons

Question 35

Which metal is commonly used in the Grignard reagent? A. Iron B. Copper C. Magnesium D. Zinc

Answer 35

Magnesium

Question 36

The reaction of benzene with chlorine in the presence of FeCl₃ gives: A. Chlorobenzene B. Benzyl chloride C. Benzene hexachloride D. Phenol

Answer 36

Chlorobenzene

Question 37

Which of the following reagents can selectively oxidize primary alcohols to aldehydes without further oxidation? A. Pyridinium chlorochromate (PCC) B. KMnO₄ C. H₂CrO₄ D. Jones reagen

Answer 37

Pyridinium chlorochromate (PCC)

Question 38

Which of the following compounds has the lowest pKa value? A. Phenol B. Trifluoroacetic acid C. Acetic acid D. Benzoic acid

Answer 38

Trifluoroacetic acid

Question 39

What is the expected product of the reaction between benzaldehyde and acetophenone in the presence of a strong base? A. Acetal B. α,β-Unsaturated ketone C. Aldol D. Metal

Answer 39

α,β-Unsaturated ketone

Question 40

The oxidation of a tertiary alcohol leads to the formation of: A. Aldehyde B. Ketone C. Carboxylic acid D. No reaction

Answer 40

No reaction

Question 41

Which of the following is an example of a 5-membered heterocyclic aromatic compound? A. Furan B. Pyridine C. Quinoline D. Coumarin

Answer 41

Furan

Question 42

Which of the following functional groups is least reactive in nucleophilic substitution reactions? A. Amide B. Alkyl halide C. Ester D. Acid chloride

Answer 42

Amide

Question 43

The synthesis of aspirin involves which type of chemical reaction? A. Oxidation B. Esterification C. Reduction D. Amide formation

Answer 43

Esterification

Question 44

What is the correct IUPAC name for the pain reliever ibuprofen? A. 2-Phenylpropanoic acid B. 2-(4-Isobutylphenyl)propanoic acid C. 2-(4-Methylphenyl)propanoic acid D. 2-Ethylbenzenepropanoic acid

Answer 44

2-(4-Isobutylphenyl)propanoic acid

Question 45

Which of the following metabolic pathways is responsible for the activation of codeine into morphine? A. O-demethylation B. Glucuronidation C. N-acetylation D. Hydrolysis

Answer 45

O-demethylation

Question 46

Which enzyme is responsible for the metabolism of over 50% of commonly used drugs? A. CYP₂C₉ B. CYP₂D₆ C. CYP₃A₄ D. CYP₁A₂

Answer 46

CYP₃A₄

Question 47

Which of the following drugs inhibits bacterial transpeptidase enzymes? A. Tetracycline B. Erythromycin C. Penicillin D. Ciprofloxacin

Answer 47

Penicillin

Question 48

The active metabolite of clopidogrel is generated by which enzyme? A. CYP2C19 B. CYP3A4 C. CYP2D6 D. CYP1A2

Answer 48

CYP2C19

Question 49

The rate-determining step in the Hofmann rearrangement involves: A. Formation of an isocyanate intermediate B. Amide hydrolysis C. Formation of a carbocation D. Dehydration

Answer 49

Formation of an isocyanate intermediate

Question 50

The standard electrode potential (E°) of a half-cell reaction is more positive when: A. It has a greater tendency to be reduced B. It has a greater tendency to be oxidized C. It has fewer electrons D. It reacts with a stronger acid

Answer 50

It has a greater tendency to be oxidized