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D&D Drugs > Drug by Adverse Reaction > Flashcards

Drug by Adverse Reaction Flashcards

(52 cards)

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1
Q

Penicillin G

A

rash, anaphylaxis, convulsions

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2
Q

Penicillin V

A

rash, anaphylaxis, convulsions

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3
Q

Penicillinase-resistant

A

rash, anaphylaxis, convulsions

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4
Q

Amoxicillin

A

diarrhea, CDAD possible

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5
Q

Cephalexin

A

allergy

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6
Q

Cefaclor, Cefuroxime

A

DDI: enhances Warfarin, anticoags possible

CDAD possible

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7
Q

Cefdinir, Ceftriaxone

A

CDAD possible

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8
Q

Vancomycin

A

chills/fever/rash

ototoxicity, renal toxicity (monitor Cp)

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9
Q

Carbapenems

A

nausea/vomiting, diarrhea, possible seizures

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10
Q

Azythromycin

A 
GI disturbances (n/v, diarrhea)
DDI's due to P450 metabolism
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11
Q

Doxycycline

A

abn tooth/bone development, fungal suprainfection
DDI with metal cations (antacids, dairy, iron)
Avoid in pregnancy

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12
Q

Minocycline

A

abn tooth/bone development, fungal suprainfection
DDI with metal cations (antacids, dairy, iron)
Avoid in pregnancy

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13
Q

Clindamycin

A

severe diarrhea

pseudomembranous colitis

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14
Q

Aminoglycoside

A

vestibular/auditory toxicity

nephrotoxicity (monitor Cp)

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15
Q

Chloramphenicol

A

bone marrow toxicity

gray baby syndrome, GI upset

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16
Q

Oxazolidinones

A

well tolerated

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17
Q

Streptogamins

A 
infusion-related pain, phlebitis
inhibits CYP3A4 (DDI's)
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18
Q

Ciprofloxacin

A

well-tolerated, CDAD possible
DDI with theophylline/antacids
Do not give to children

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19
Q

Levofloxacin

A

well-tolerated, CDAD possible
DDI with theophylline/antacids
Do not give to children

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20
Q

Nitrofurantoin

A

GI

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21
Q

Metronidazole

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A

nausea, headache, GI

Antabuse-like rxn

22
Q

Sulfamethoxazole/Trimethoprim

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A

hypersensitivity skin rxns

decreased H2O solubility of metabolites

23
Q

Isoniazid

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A

hepatotoxicity, neuritis, allergic rxns

24
Q

Rifampin

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A

liver function impairment
colors excretions orange-red
induces CYP1A2, 2C9-19, 3A4

25
Ethambutol
optic neuritis, rash | avoid in children
26
Pyrazinamide
hepatotoxicity, hyperuricemia
27
Streptomycin
8th nerve toxicity
28
Amphotericin
fever/chills with infusion | nephrotoxicity
29
Nystatin
well tolerated
30
Caspfungin
rash, pruritus, n/v with infusion
31
Fluconazole
well tolerated
32
Terbinafine
headache, diarrhea, rash | inhibits CYP450
33
Flucytosine
n/v, rashes, bone marrow depletion
34
Griseofulvin
hypersensitivity rxns, GI distress, confusion
35
Acyclovir
minor toxicities (headache, n/v)
36
Valacyclovir
minor toxicities (headache, n/v)
37
Entacavir
well tolerated
38
Tenofovir
well tolerated usually | lactic acidosis, HSM in HIV pt's
39
Interferon-α
flu-like symptoms, bone marrow depression, neurobehavioral changes
40
Ribavirin
low aerosol toxicity | systemic toxicity: anemia, bone marrow depression
41
Telaprevir, Boceprevir
rash common (possibly severe)
42
Sufosbuvir
well tolerated overall | fatigue, nausea, insomnia
43
Emtricitabine
best tolerated HIV, hypersensitivity
44
Tenofovir
well tolerated HIV, hypersensitivity
45
Efavirenz
CNS effects
46
Atazanavir
rash, bilirubinemia/jaundice
47
Darunavir
severe rash/ DJ syndrome
48
Ritonavir
Gi, hepatotoxicity
49
Raltegravir
relatively well tolerated GI upset, sweating DDI increase with glucuronidation inducer
50
Enfuvirtide
injection site inflammation
51
Maraviroc
mild GI, HA, URI, insomnia, rash | DDI with ART that inhib/induce CYP3A4
52
Antipseudomonal
diarrhea, CDAD possible

D&D Drugs (7 decks)

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