Drug by Type Unit 2 Flashcards

1
Q

Penicillins

A

Cell Wall Synthesis Inhibitors

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2
Q

Cephalosporins

A

Cell Wall Synthesis Inhibitors

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3
Q

Carbapenems

A

Cell Wall Synthesis Inhibitors

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4
Q

Monobactams

A

Cell Wall Synthesis Inhibitors

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5
Q

Vancomycin

A

Cell Wall Synthesis Inhibitor

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6
Q

Penicillin G

A

Prototypical Penicillin

Cell Wall Synthesis Inhibitor

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7
Q

Penicillin V

A

Prototypical Penicillin

Cell Wall Synthesis Inhibitor

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8
Q

Methicillin

A

Penicillinase-Resistant Penicillin

Cell Wall Synthesis Inhibitor

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9
Q

Nafcillin

A

Penicillinase-Resistant Penicillin

Cell Wall Synthesis Inhibitor

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10
Q

Oxacillin

A

Penicillinase-Resistant Penicillin

Cell Wall Synthesis Inhibitor

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11
Q

Dicloxacillin

A

Penicillinase-Resistant Penicillin

Cell Wall Synthesis Inhibitor

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12
Q

Amoxicillin

A

Extended-spectrum Penicillin

Cell Wall Synthesis Inhibitor

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13
Q

Ampicillin

A

Extended-spectrum Penicillin

Cell Wall Synthesis Inhibitor

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14
Q

Piperacillin

A
Antipsuedomonal Penicillin
(Cell Wall Synthesis Inhibitor)
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15
Q

Amoxicillin-Clavulanate

A

Penicillin plus β-lactamase inhibitor

Cell Wall Synthesis Inhibitor

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16
Q

Piperacillin-Tazobactam

A

Penicillin plus β-lactamase inhibitor

Cell Wall Synthesis Inhibitor

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17
Q

Cephalexin

A

1st Generation Cephalosporin

Cell Wall Synthesis Inhibitor

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18
Q

Cefazolin

A

1st Generation Cephalosporin

Cell Wall Synthesis Inhibitor

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19
Q

Cefuroxime

A

2nd Generation Cephalosporin

Cell Wall Synthesis Inhibitor

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20
Q

Ceftriaxone

A

3rd Generation Cephalosporin

Cell Wall Synthesis Inhibitor

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21
Q

Aminoglycosides

A

Protein-Synthesis Inhibitors

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22
Q

Tetracyclines

A

Protein-Synthesis Inhibitors

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23
Q

Macrolides

A

Protein-Synthesis Inhibitors

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24
Q

Lincomycins

A

Protein-Synthesis Inhibitors

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25
Q

Synthetic Agents

A

Protein-Synthesis Inhibitors

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26
Q

Doxycycline

A

Tetracycline

Protein-Synthesis Inhibitor

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27
Q

Erythromycin

A

Macrolide
(Protein-Synthesis Inhibitor)
Don’t give to pregnant women

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28
Q

Azithromycin

A

Macrolide

Protein-Synthesis Inhibitor

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29
Q

Clarithromycin

A

Macrolide

Protein-Synthesis Inhibitor

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30
Q

Clindamycin

A

Lincomycin

Protein-Synthesis Inhibitor

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31
Q

Chloramphenicol

A

Synthetic Agent

Protein-Synthesis Inhibitor

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32
Q

Quinolones & Fluoroquinolones

A

Inhibitors of DNA Function

33
Q

Metronidazole

A

Inhibitor of DNA Function

34
Q

Ciprofloxacin

A

Quinolone/Fluoroquinolone

Inhibitor of DNA Function

35
Q

Levofloxacin

A

Quinolone/Fluoroquinolone

Inhibitor of DNA Function

36
Q

Moxifloxacin

A

Quinolone/Fluoroquinolone

Inhibitor of DNA Function

37
Q

Fun Fact

A

Cell Membrane Disruptors exist too. That is all :)

38
Q

Zanamivir

A

Neuraminidase Inhibitor for Influenza

39
Q

Oseltamivir

A

Neuraminidase Inhibitor for Influenza

40
Q

Rimantadine

A

Block of M2 Proton Channel for Influenza [Note: No longer recommended due to high resistance rates]

41
Q

Acyclovir

A

Inhibitor of Viral DNA Polymerase for Herpes simplex/varicella/zoster

42
Q

Valacyclovir

A

Inhibitor of Viral DNA Polymerase for Herpes simplex/varicella/zoster

43
Q

How to treat CMV (Cytomegalovirus)?

A

Inhibit the viral DNA Polymerase (ex. Ganciclovir, Foscarnet)

44
Q

How to treat Hepatitis B/C?

A

HCV Protease Inhibitors (ex. Ribavirin, Interferon-α, or Bocepravir)

45
Q

Amphotericin B

A

Anti-Fungal Agent

Cell Membrane Disruption

46
Q

Fluconazole

A

Ergosterol synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

47
Q

Itraconazole

A

Ergosterol synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

48
Q

Ketoconazole

A

Ergosterol synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

49
Q

Clotrimazole

A

Ergosterol synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

50
Q

Terbinafine

A

Squalene synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

51
Q

Ergosterol synthesis inhibitors

A

Inhibitors of Anti-Fungal Cell Wall/Membrane Synthesis

52
Q

Squalene synthesis inhibitors

A

Inhibitors of Anti-Fungal Cell Wall/Membrane Synthesis

53
Q

β (1,3)-D-glucan synthesis inhibitors

A

Inhibitors of Anti-Fungal Cell Wall/Membrane Synthesis

54
Q

Nitrofurantoin

A

Quinolone/Fluoroquinolone

Inhibitor of DNA Function

55
Q

Metronidazole

A

Quinolone/Fluoroquinolone

Inhibitor of DNA Function

56
Q

Sulfamethoxazole/Trimethoprim

A

Sulfonamide

Inhibit folate metabolism

57
Q

Isoniazid

A

Anti-TB Agent

58
Q

Rifampin

A

Anti-TB Agent

59
Q

Ethambutol

A

Anti-TB Agent

60
Q

Pyrazinamide

A

Anti-TB Agent

61
Q

Streptomycin

A

Anti-TB Agent (aminoglycosides)

62
Q

Nystatin

A

Cell Membrane Disruption

63
Q

Flucytosine

A

Thymidylate synthesis inhibitor

Inhibitor of Anti-Fungal Cell Wall Synthesis

64
Q

Griseofulvin

A

Inhibitor of Fungal Microtubules

65
Q

Entacavir

A

For Hepatitis

66
Q

Tenofovir

A

For Hepatitis, HIV

67
Q

Interferon-α

A

For Hepatitis

68
Q

Ribavirin

A

For Hepatitis

69
Q

Telaprevir

A

For Hepatitis

70
Q

Boceprevir

A

For Hepatitis

71
Q

Sufosbuvir

A

For Hepatitis

72
Q

Emtricitabine

A

for HIV (Reverse Transcriptase Inhibitor)

73
Q

Efavirenz

A

for HIV (Nonnucleoside RTI)

74
Q

Atazanavir

A

for HIV (Protease Inhibitor)

75
Q

Darunavir

A

for HIV (Protease Inhibitor)

76
Q

Ritonavir

A

for HIV (Protease Inhibitor)

77
Q

Enfuviritide

A

for HIV (Fusion Inhibitor)

78
Q

Raltegravir

A

for HIV (Integrase Inhibitor)

79
Q

Maraviroc

A

for HIV (Fusion Inhibitor)