Drug Discovery Flashcards

1
Q

Resposta de coagulação

A

Clotting response

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2
Q

Retângulo, oval

A

Rectangles, ovals

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3
Q

Necessidades medicas não atendidas

A

Unmet medical needs

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4
Q

Partes interessadas, setores, acionistas

A

Stakeholders

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5
Q

Testes de potencia e eficacia (trial)

A

Assays

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6
Q

Vai passar por testes toxicológicos, ser submetido a

A

Will undergo toxicology testing

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7
Q

Aprimore seu conhecimento

A

Brush up on your knowledge

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8
Q

Programa de estudos

A

Syllabus

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9
Q

Se uma molécula baixa o colesterol

A

If a molecule lowers cholesterol

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10
Q

Entidades

A

Entiti

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11
Q

Aprovação

A

Approval

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12
Q

Grande risco, terrível

A

Dire risk

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13
Q

Bastante/razoavelmente comum

A

Fairly commom

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14
Q

2/3

A

Two thirds

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15
Q

ANDA

A

Abbreviated New drug apllication

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16
Q

Teste de bioquevalencia

A

Bioequivalence testing

17
Q

A forma genérica se comporta igual a versão original

A

Generic form behaves the same as the original version

18
Q

INN

A

International non-proprietary name (propraietéri)

19
Q

API

A

Active pharmaceutical ingredient

20
Q

Ligação de hidrogênio

A

Hydrogen bond

21
Q

Animais e aves de uma fazenda

A

Livestock (laivstock)

22
Q

Indústria pecuaria

A

Livestock industry

23
Q

Exercer

A

Exert

24
Q

Cadeias hidrocarbonicas

A

Hydrocarbon chains

25
Q

Render, produzir, ocasionar um benefício terapêutico

A

Yield a therapeutic benefit

26
Q

ADR

A

Adverse drug reactions

27
Q

Efetiva para tratar uma doença

A

Efective in treating a disease

28
Q

RAMs podem surgir de interações no alvo

A

ADRs can arrise from on target interactions

29
Q

Sonolencia

A

Drowsiness

30
Q

MTC and MEC

A

Maximum tolerated concentration, minimum effective concentration

31
Q

Razão, proporção

A

Ratio (reitio)

32
Q

Intervalo

A

Range

33
Q

MTC/MEC (ratio)

A

TI - therapeutic index

34
Q

Trato gastrointestinal

A

GI tract

35
Q

Corrente sanguínea

A

Bloodstream

36
Q

Sítio

A

Site

37
Q

Metabólito

A

Metabolite

38
Q

Excreção renal

A

Renal excretion (rinou)