Drug Reactions

Question 1

cocaine, sumatriptan, ergot alkaloids

Answer 1

coronary vasospasm

Question 2

VANComycin Adenosine, Niacin, Ca++ channel blockers

“VANC”

Answer 2

cutaneous flushing

Question 3

doxorubicin (adriamycin), daunorubicin

Answer 3

dilated cardiomyopathy

Question 4

class III (sotalol) & class IA (quinidine) antiarrhythmics

Answer 4

torsades de pointes

Question 5

Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone

Answer 5

agranulocytosis

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

Question 6

chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole

Answer 6

aplastic anemia

Question 7

methyldopa, penicillin

Answer 7

direct coomb’s - positive hemolytic anemia

Question 8

chloramphenicol

Answer 8

gray baby syndrome

Question 9

Isoniazid (INH), Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

Answer 9

hemolysis in G6PD deficient patients

“hemolysis IS PAIN”

Question 10

Phenytoin, Methotrexate, Sulfa drugs

Answer 10

megaloBLASTic anemia

“having a BLAST with PMS”

Question 11

OCPs (estrogens)

Answer 11

thrombotic complications

Question 12

ACE inhibitors

Answer 12

cough

remember – ARBs (losartan) = no cough

Question 13

BLeomycin, Amiodarone, Busulfan

Answer 13

pulmonary fibrosis

“its hard to BLAB when you have pulmonary fibrosis”

Question 14

erythromycin

Answer 14

acute cholestatic hepatitis, jaundice

Question 15

Halothane, Amanita phalloides, Valproic acid, Acetaminophen

“liver HAVAc”

Answer 15

focal to massive hepatic necrosis

Question 16

INH (Isonizaid)

Answer 16

hepatitis

Question 17

clindamycin, ampicillin

Answer 17

pseudomembranous colitis

Question 18

glucocorticoid withdrawal (HPA suppression)

Answer 18

adrenocortical insufficiency

Question 19

Spironolactone, Digitalis, Cimetidine, chronic Alcohol use, estrogens, Ketoconazole

Answer 19

gynecomastia

“Some Drugs Create Awkward Knockers”

Question 20

tamoxifen, clomiphene

Answer 20

hot flashes

Question 21

niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids

Answer 21

hyperglycemia

Question 22

lithium, amiodarone, sulfonamides

Answer 22

hypothyroidism

Question 23

glucocorticoids, protease inhibitors

Answer 23

fat redistribution

Question 24

phenytoin, verapamil

Answer 24

gingival hyperplasia

Question 25

furosemide, thiazides, niacin, cyclosporine

Answer 25

gout

Question 26

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Ingerferon-alpha, Penicillamine, Statins, Glucocorticoids

Answer 26

myopathies "Fish N CHIPS Give you myopathies"

Question 27

corticosteroids, heparin

Answer 27

osteoporosis

Question 28

Sulfonamides, Amiodarone, Tetracycline

Answer 28

photosensitivity "SAT for a photo"

Question 29

Penicillin, Ethosuximide, Carbamazepine, Sulfa drugs, Lamotrigine, Allopurinol, Phenytoin, Phenobarbital

Answer 29

rash (stevens-johnson sundrome) "bad rash after a PEC SLAPP"

Question 30

Hydralazine, INH, Procainamide, Phenytoin

Answer 30

SLE "its not HIPP to have lupus"

Question 31

tetracyclines

Answer 31

teeth (kids)

Question 32

fluoroquinolones

Answer 32

tendonitis, tendon rupture, cartilage damage

Question 33

lithium, demeclocycline

Answer 33

diabetes insipidus

Question 34

expired tetracycline

Answer 34

Fanconi's syndrome (remember ass. w/ amino acid Cysteine)

Question 35

cyclophosphamide, ifosfamide prevent by?

Answer 35

hemorrhagic cystitis prevent by coadministering w/ mesna

Question 36

methicillin, NSAIDs, furosemide

Answer 36

interstitial nephritis

Question 37

carbamazepine, cyclophosphamide

Answer 37

SIADH

Question 38

quinidine, quinine

Answer 38

cinchonism

Question 39

antipsychotics, reserpine, methoclopramide

Answer 39

parkinson-like syndrome

Question 40

Isoniazid, Buproprion, Imipenem/cilastatin, Tramadol, Enflurane, Methoclopramide

Answer 40

seizures "with seizures, I BITE My tongue"

Question 41

antipsychotics

Answer 41

tardive dyskinesia

Question 42

atropine, TCAs, H1-blockers, neuroleptics

Answer 42

antimuscarinic

Question 43

metronidazole, certain cephalosprins, procarbazine, 1st gen sulfonylureas

Answer 43

disulfiram-like reaction

Question 44

aminoglycosides, vancomycin, loop diuretics, cisplatin

Answer 44

nephrotoxicity/ototoxicity