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Flashcards in Drugs Deck (12)
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1

brimonidine

adrenergic agonist, catecholamine
alpha 2 selective
decrease BP and HR, causes vasoconstriction
hypertension

2

clonidine

adrenergic agonist, catecholamine
alpha 2 selective
decrease Bp and HR, doesn't cause vasoconstriciton
dry mouth, dedation, impotence, withdrawal, dramatic rebound HTN when stopped suddenly
hypertension

3

isoproterenol

beta adrenergic agonist, catecholamine
non selective
stimulation of autonomic receptors
cardiovascular, asthma

4

epinephrine/norepineprine

adrenergic agonsit, endogenous ligand, catecholamine
non selective
epi works on beta 2, NE doesn't so safe for heart contractive w/o relaxation of lungs
heart and lungs; NE: ADHD, depression

5

tetrahydrolozine

adrenergic agonist, noncatecholamine
alpha agonist
constricts BV o reduce red eye

6

phenylephrine/pseudoephedrine

adrenergice agonist, noncatecholamine
alpha 2 agonist
decongestant, stimulation of automonic receptors, alpha and beta stimulation

7

albuterol

adrenergic agonist, noncatecholamine
beta2 agonist
smooth muscle relaxation in lungs-bronchodialtion
asthma and COPD treatment

8

imipramine

-tricyclic antidepressant/adrenergic reuptake inhibitor
-block reuptake transporter (amine uptake pump) on pre synaptic cell and prevents NE from being taken from synaptic space and brought to pre-syn
-effect on neurons, not so much muscles

9

prazosin

-tamusolin in elderly men
-alpha-adrenergic antagonist
-alpha 1 selective (blocker), sympathoplegic, acts on arterioles
-adrenoreceptor blocker, prevents contraction, blockage of autonomic receptors (alpha), dilate vessels and blocs sympathetic system
-mild tachycardia (abnormal heartrate), reduced sympathetic tone
-benign prostate hyperplasia (prevent urine), mild HT as monotherapy, mod/sev HT (beta1 combo therapy)

10

propanolol

-beta-adrenergic antagonist
-non selective, beta blocker
-contracts bronchia smooth muscle, relaxes heart, decrease HR and BP, blocakde of automonic receptors
-orthostatic hypotension, tachycardia, HA
-glaucoma, silent angia, acute coronary syndrome, cardiac arrhythmia

11

labetalol

alpha 1 and beta adrenergic antagonist
-non selective, sympathaloplegic
-adrenoreceptor blocker, prevents contraction, blocks alpha1 receptor
-moderate toxicity, asthma, bradycardia, heart failure
-mild HT as monotherapy, mod/sev HT (beta 1-combo therapy)

12

atenolol (metaprolol)

beta-adrenergic antagonist
-beta 1 selective beta blocker
-reduction in BP, reduction in cardiac work
-orthostatic hypotension, tachycardia, HA,
-silent angia, acute coronary syndrome, cardiac arrhythmia