Drugs

Question 1

Intoxication of what cause vertical AND horizontal nystagmus?

Treat how?

Answer 1

PCP

Haldol to subdue
Acidify urine to inc excretion

Question 2

What are the MAO-Is?

can cause what?

Answer 2

Phenylzine
Tranylcypromine
Selegeline

HTN crisis when mixed w/red wine and cheese

Question 3

Tell-tale symptom of opiate withdrawal?

Answer 3

Yawning

Question 4

What is in a B52 shot?

Answer 4

Benadryl
Haldol
Ativan

Question 5

What are the potent typical antipsychotic?

Weaker?

Answer 5

Haloperidol > fluphenazine

Thioridazine, Chlorpromazine

Question 6

Blocking dopamine in the nigrostriatal tract causes what?

Answer 6

Parkinsonism and EPS

Question 7

What does Buproprion treat?

Answer 7

Smoking cessation
Depression
Prevents weight gain

Question 8

What are examples of acute dystonia?

Answer 8

Involuntary muscle contraction

Torticollis, oculogyric crisis, hand wringing

Question 10

Serotonin Syndrome has what key feature?

Answer 10

Hyperreflexia

Myoclonus

Question 11

+ symptoms of antipsychotics d/t what pathology’s?

Answer 11

Mesolimbic D2C receptors (dopamine)

Question 12

How to treat TCA overdose?

Answer 12

Sodium bicarbonate

Question 13

Dilated pupils, psychosis and tachycardia indicates what intoxication?

Answer 13

Cocaine

Question 14

What drug has symptoms of Flashbacks?

Answer 14

LSD

Question 15

• symptoms of anti-psychotics has what pathophys?

Answer 15

5-HT1 serotonin

Question 18

Neuroleptic malignant hyperthermia has what key feature?

Answer 18

Muscle rigidity

Question 20

Pt that has been taking benzo’s for awhile and suddenly presents w/seizures after not taking it for 3-4 days, what is going on?

Answer 20

Withdrawal

Question 21

What are the 1st symptoms of alcohol withdrawal?

When do they occur?

Answer 21

Diastolic HTN and tachycardia

48-72 hours since last drink

Question 22

SE of Trazadone?

Answer 22

Sleep aid, priapism

Question 23

What meds treat public speaking anxiety?

Answer 23

Propanolol
Nadolol
Atenolol

Question 25

What antipsychotic causes increased weight gain and diabetes?

Answer 25

Olanzapine

Question 26

Quetiapine SEs?

Answer 26

Weight gain
QTc prolongation
Somnolence

Question 27

What are the symptoms of opiate withdrawal?

Answer 27

Pain
N/V/D
Irritable, runny nose

Question 28

Valproate has what SE?

Answer 28

Spina bifida
Pancreatitis
Dec platelets
Agranulocytosis

Question 29

TCA side effects?

Answer 29

Convulsions —> seizures (antagonize GABAa)
Coma
Cardiac —> Block fast Na Channels causes QRS and QT prolongation

Question 29

What is akathisia? Treat how?

Answer 29

Subjective feeling of restless or urge to move Decrease dose, benztropine

Question 30

Atypical anti-psychotics have what major side effect?

Answer 30

QTc prolongation | EPS

Question 31

What are the SSRIs? Side effects?

Answer 31

Escitalopram Sertraline Fluoxetine Paroxetine Dec Libido Delayed Ejaculation Serotonin syndrome

Question 32

What are the TCAs? Used to treat what most often?

Answer 32

“Tryptilines” Imipramine Desipramine Doxepin Enuresis and Neuropathic pain

Question 33

What is in a coma cocktail?

Answer 33

DON’T get blackout D50 Oxygen Naloxone Thiamine

Question 35

SE of Mirtazapine?

Answer 35

Appetite —> especially geriatrics

Question 35

MOA of atypical antipsychotics?

Answer 35

Block Serotonin receptors (5HT1)