Drugs Flashcards
(60 cards)
1
Q
alkylators: general
A
- nitrogen mustards
- platinum analogs
- triazenes
2
Q
alkylators: nitrogen mustards
A
- nitrogen mustard
- cyclophosphamide
- ifosfamide
- chlorambucil
- melphalan
3
Q
alkylators: platinum analogs
A
- cisplatin
- carboplatin
- oxaliplatin
4
Q
alkylators: triazenes
A
- dacarbazine
5
Q
antrhacyclines
A
- doxorubicin
- daunotubucin
6
Q
antimetabolics
A
- methotrexate
- 5-fluorouracil
- hydroxyurea
7
Q
antimetabolic analogs
A
- pyrimidine analogs: cytarabine (ara-c), gemcitabine
- purine analogs: fludarabine
8
Q
anti-tumor antibiotics
A
- bleomycin
9
Q
plant alkaloids: general
A
- vinca alkaloids
- taxanes
- camptothecins
10
Q
plant alkaloids: vinca alkaloids
A
- vincristine
- vinblastine
- vinorelbine
11
Q
plant alkaloids: taxanes
A
- paclitaxel
- docetaxel
12
Q
plant alkaloids: camptothecins
A
- irinotecan
13
Q
hormones
A
- glucocorticoids: dexamethasone, prednisone
- androgens: danazol
14
Q
anti-horomones
A
- anti-androgens (receptor antagonists)
- anti-estrogens (receptor antagonists)
- aromatase inhibitors
- LH-RH agonists
15
Q
anti-horomones: anti-androgens
A
- flutamide
- bicalutamide
16
Q
anti-horomones: anti-estrogens
A
- tamoxifen
- raloxifene
17
Q
anti-horomones: aromatase inhibitors
A
- anastrozole
- letrozole
- exemestane
18
Q
anti-horomones: LH-RH agonists
A
- leuprolide
- goserelin
19
Q
monoclonal antibodies
A
- trastuzumab
- bevacizumab
- cetuximab
- rituximab
- eculizumab
- brentuximab vedotin
- ipilimumab
- nivolumab
20
Q
trastuzumab
A
anti-HER2
21
Q
bevacizumab
A
anti-VEGF
22
Q
cetuximab
A
anti-EGFR
23
Q
rituximab
A
anti-CD20
24
Q
eculizumab
A
anti-compliment C5
25
brentuximab vedotin
anti-CD30 conjugated to microtubule disrupting agent
26
ipilimumab
anti-CTLA4
27
nivolumab
anti-PD-1
28
small molecule inhibitors
- imatinib
- erlotinib
- ibrutinib
29
imatinib
BCR-ABL inhibitor
30
erlotinib
EGFR inhibitor
31
ibrutinib
Bruton's tyrosine kinase inhibitor
32
imids
- thalidomide
| - lenalidomide
33
demethylating agents
- azacytidine
| - decitabine
34
proteasome inhibitors
- bortezomib
35
vitamin A analog
- all trans-retinoic acid (ATRA)
36
arsenical
- arsenic trioxide (ATO)
37
anticoagulants
- heparins
- direct thrombin inhibitors
- direct factor Xa inhibitors
- thrombolytics
- vitamin K antagonists
- anti-platelet agens
- GpIIb/IIIa antagonists
38
anticoagulants: heparins
- unfractionated
- low molecular weight: enoxaparin, dalteparin
- fondaparinux
39
anticoagulants: direct thrombin inhibitors
- lepirudin
- argatroban
- dabigatran (reversal: idarucizumab)
40
anticoagulants: direct factor Xa inhibitors
- rivaroxaban (reversal: andexanet-alpha)
41
anticoagulants: thrombolytics
- recombinant tPA
42
anticoagulants: vit K antagonists
- warfarin
43
anticoagulants: anti-platelet agents
- aspirin
- clopidogrel
- prasugrel
- NSAIDs (ibuprogen)
44
anticoagulants: GpIIb/IIIa antagonists
- abiciximab
45
pro-coagulants
- vitamin K
- recombinant factor VIIa
- desmopressin acetate (DDAVP)
46
anti-fibrinolytics
- aminocaproic acid
47
thrombopoietin mimetics
- romiplostim
| - eltrombopag
48
anti-emetics
- serotonin antagonists
- NK-1 antagonists
- benzodiazepines
- glucocorticoids
- dopaminergic antagonists
49
anti-emetics: serotonin antagonists
- ondansetron
50
anti-emetics: NK-1 antagonists
- aprepitant
51
anti-emetics: benzodiazepines
- lorazepam
52
anti-emetics: glucocorticoids
- dexamethasone
53
anti-emetics: dopaminergic antagonists
- prochlorperazine
| - metoclopramide
54
growth factors
- ESAs: epoetin alfa, darbepoetin alfa
| - G-CSF: filgrastim, pegfilgrastim
55
supportive to growth factors
- leucovorin
- mesna
- dexrazoxane
- atropine
- protamine sulfate
- allopurinol
- rasburicase
- diphenhydramine
56
blood bank products
- rbcs
- fresh frozen plasma
- platelets
- granulocytes
- cryoprecipitate
- anti-D immune globulin
- prothrombin complex concentrates
- factor concentrates and recombinant coagulation factors
- albumin
- IVIg
57
anti-D immune globulin
- RhoGAM
| - WinRHo
58
prothrombin complex concentrates
- activated PCC = 3-factor
| - unactivated PCC = 4-factor
59
factor concentrates
- VIII
| - IX
60
recombinant coagulation factors
- VIII
- IX
- VIIa
