markers and chemo

Question 1

human hsc stem cell markers

Answer 1

Lin- Kit+ CD34+

Question 2

paroxysmal nocturnal hemoglobinuria

Answer 2

CD55 and CD59 NOT expressed

Question 3

myeloid markers

Answer 3

• myeloperoxidase and lysozyme

- CD13, CD 33, Cd117

Question 4

lymphoid markers

Answer 4

• Tdt

Question 5

B markers

Answer 5

• CD10, CD19, CD20

Question 6

T markers

Answer 6

• CD2, CD3, CD4, CD5, CD8

Question 7

HL Reed Sternberg Cell

Answer 7

CD30 and CD15

Question 8

non classical HL (nodular lymphocyte)

Answer 8

CD20

Question 9

CLL immunophenotype

Answer 9

CD19, CD20, CD23, CD5

Question 10

carcinoma IHC

Answer 10

CD, EMA

Question 11

breast

Answer 11

ER, PR

Question 12

prostate

Answer 12

PSA

Question 13

lymphoma

Answer 13

CD45

Question 14

melanoma

Answer 14

S-100

Question 15

germ cell

Answer 15

beta-HCG, AFP

Question 16

soft tissue, carcinoma

Answer 16

vimentin

Question 17

GPIb

Answer 17

VWF receptor

Question 18

GPIa/IIa

Answer 18

collagen receptor

Question 19

GPIIb/IIIa

Answer 19

fibrinogen

Question 20

APL translocation

Answer 20

t(15, 17) (PML-RAR)

Question 21

AML prognosis (good)

Answer 21

t(8, 21), inv(16), t(15, 17)

NPM1, CEBPA

Question 22

AML prognosis (bad)

Answer 22

11q23 trans, del 5, del 7

FLT3

Question 23

ALL prognosis (good)

Answer 23

t(12, 21), hyperploidy

Question 24

ALL prognosis (bad)

Answer 24

t(9, 22), t(4, 11), 11q23 trans, hypoploidy

Question 25

CLL prognostics (bad)

Answer 25

unmutated, CD38, ZAP20, 17p del, 11q del

Question 26

CML translocation

Answer 26

t(19, 22), BCR-ABL1

Question 27

APL treatment

Answer 27

- ATRA and ATO

Question 28

AML treatment

Answer 28

cytarabine and anthracycline

Question 29

ALL treatment

Answer 29

- vincristine, glucocorticoid, anthracycline, L-asparaginase, cytarabine, cyclophosphamide, methotrexate - TK inhibitor in Ph+

Question 30

NHL indolent treatment

Answer 30

rituximab combo

Question 31

NHL aggressive treatment

Answer 31

- R-CHOP | - rituximab, cyclophosphamide, doxirubicin, vincristin, prednisone

Question 32

HL standard treatment

Answer 32

- ABVD | - adriamycin, bleomycin, vinblastine, dacarbazine

Question 33

HL other

Answer 33

- nitrogen mustard, brentuximab, immune checkpoint inhibitor

Question 34

CLL therapy

Answer 34

- oral: fludarabine, chlorambucil - rituximab and alemtuzomab - ibrutinib

Question 35

multiple myeloma therapy

Answer 35

- melphalan and cyclophosphamide - prednisone and detramethasone - thalidomide and lenalidomide - bortezomib

Question 36

5q MDS therapy

Answer 36

lenalidomide

Question 37

CML therapy

Answer 37

TKi, IFNalpha

Question 38

PV therapy

Answer 38

aspirin, hydroxyurea, IFN alpha JAK2i

Question 39

ET therapy

Answer 39

hydroxyurea, aspirin

Question 40

PMF theraoy

Answer 40

mephalan, busulfan, hydroxyurea, JAK2i