Drugs and usual doses

Question 1

Schedule for Percocet

Answer 1

II- high potential for abuse

Question 2

Schedule for Vicodin

Answer 2

III- moderate potential for abuse

Question 3

Schedule for Tylenol #3

Answer 3

III moderate potential for abuse

Question 4

Schedule for Darvocet

Answer 4

IV low potential for abuse

Question 5

Percocet 5/325?

Answer 5

oxycodone/ acetaminopen 5mg/325mg QID

Question 6

Roxicet?

Answer 6

Oxycodone/acetaminopen

• 5mg/325mg/ 5mL
• essentially a liquid form of Percocet that is good for pediatric patients

Question 7

What is the difference between Percocet and Percodan?

Answer 7

• Percocet has 325 acetaminophen

- Percodan haas 325 mg of ASA

Question 8

Vicodin 5/500

Answer 8

hydrocodone/acetaminophen 5mg/500mg

QID

Question 9

Tylenol #3

Answer 9

codeine/acetaminophen 30mg/300mg

QID

Question 10

Darvocet N100

Answer 10

propoxyphene/acetaminophen
-100mg/650mg

q4

Question 11

Ultram

Answer 11

Tramadol 50mg

QID

Question 12

Toradol

Answer 12

Ketorolac 10mg

-an NSAID that should not be used more than 5 days due to possible significant side effects

Question 13

Darvon

Answer 13

-propoxyphene

Question 14

OxyContin

Answer 14

oxycodone extended release

Question 15

Morphine sulfate

Answer 15

2-4mg IV QID.

-usually used for very painful dressing changes or bedside debridement

Question 16

MS Contin

Answer 16

morphine sulfate extended release 15-30mg

Question 17

Dilaudid

Answer 17

hydromorphone

Very strong drug

Question 18

What are the therapeutic effects seen with acetaminophen (2)

Answer 18

analgesic and anti-pyretic

Question 19

What is the maximum daily dose of acetaminophen

Answer 19

4grams

Question 20

What therapeutic effects are seen with most NSAIDS (3)

Answer 20

analgesic, anti-pyretic, anti-inflammatory

Question 21

What pathway do NSAIDS work on

Answer 21

cyclooxygenase

NSAIDS nonselectively inhibit both COX-1 and COX-2

Question 22

What is the most common side effect of NSAIDs

Answer 22

GI disturbance ( especially if it is a strong COX-1 inhibitor)

Question 23

What is the only FDA approved COX-2 inhibitor

Answer 23

celecoxib

-others were withdrawn due to increased risk of heart attack and stroke

Question 24

Which NSAIDS only have anti-inflammatory effects

Answer 24

Indomethacin and tolmetin

Question 25

Do NSAIDs decrease joint destruction

Answer 25

no they only decrease inflammation

Question 26

Do NSAIDs affect bone healing

Answer 26

NSAIDs and COX-2 inhibitors may inhibit bone healing via their anti-inflammatory effects

Question 27

What NSAID causes irreversible inhibition of platelet aggregation

Answer 27

aspirin

Question 28

What NSAID does not inhibit platelet aggregation

Answer 28

the COX-2 inhibitor celebrex

Question 29

What is the only IV NSAID

Answer 29

ketorolac (toradol)

Question 30

What NSAID is often given during surgery or immediately post-op to decrease pain and inflammation

Answer 30

-Toradol 30mg IV

Question 31

What are the NSAIDs with the least neprotoxicity

Answer 31

- celebrex - Relafen - Lodine

Question 32

What is the effect of NSAIDs for a patient with asthma

Answer 32

- can increase the symptoms of asthma

Question 33

What are the safest NSAIDs for a patient with asthma

Answer 33

and ketoprofen

Question 34

Which NSAIDs treat collagen vascular disease

Answer 34

ibuprofen, sulindac, tolmetin

Question 35

Which NSAIDs are not renally cleared

Answer 35

indomethacin and sulindac

Question 36

What are the cardiovascular effects of NSAIDS

Answer 36

they can cause vasoconstriction and increase blood pressure

Question 37

Which NSAIDs have the least cardiovascular effects

Answer 37

diclofenac and ketoprofen

Question 38

Which NSAIDs are the most hepatotoxic

Answer 38

Ibuprofen, naproxen and diclofenac

Question 39

What should be given for an indomethacin overdose

Answer 39

benadryl -decreaes serotonin and histamine release

Question 40

What is arthrotec

Answer 40

diclofenac and misoprostol -an NSAID with protection for the stomach

Question 41

What is the anti-inflammatory dose of ibuprofen

Answer 41

1200-3200 mg/day in divided doses

Question 42

What NSAIDs work on both the lipooxygenase and cyclooxygenase pathways

Answer 42

-ketoprofen and diclofenac

Question 43

What is the difference between Cataflam and Voltaren

Answer 43

- Cataflam is diclofenac potassium and has in immediate release - Voltaren is diclofenac sodium and has a delayed release

Question 44

What are the only pro-drugs for NSAIDs

Answer 44

nabumetone and sulindac

Question 45

What is the only nonacidic NSAID

Answer 45

nabumetone

Question 46

Which NSAIDs have fewer pulmonary problems

Answer 46

ketoprofen and diclofenac

Question 47

What are the 6 classification types of NSAIDs

Answer 47

- Salicylic acid derivatives - Propionic acid - Acetic acid - Fenamates - Enolic/-oxicams - Cox2 inhibitors

Question 48

What are the salicylic acid medications (4)

Answer 48

- ASA - diflunisal - salsalate - Trilisate

Question 49

What are the propionic acid medications (5)

Answer 49

- flurbiprofen - ibuprofen - ketoprofen - naproxen - oxaprozin

Question 50

What are the acetic acid medications (7)

Answer 50

- diclofenac - etodolac - indomethacin - ketorolac - nabumetone - sulindac - tolmetin

Question 51

Enolic acid/ oxicams (2)

Answer 51

meloxicam and piroxicam

Question 52

Cox-2 inhibitors

Answer 52

celecoxib