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Drugs - FA Flashcards

(38 cards)

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1
Q

Leuprolide

A

GnRH analog

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2
Q

Anastrazole, Letrozole

A

Aromatase inhibitor

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3
Q

Exemestane

A

Aromatase inhibitor

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4
Q

Ulipristal

A

Progesterone antagonist

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5
Q

Terbutaline

A

Beta-2 agonist (relax uterus)

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6
Q

Ritodrine

A

Beta-2 agonist (relax uterus)

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7
Q

Danazol

A

Partial agonist at androgen receptors

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8
Q

Flutamide

A

Competitive inhibitor at androgen receptors

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9
Q

Ketoconazole (androgens)

A

Inhibits 17,20 desmolase (steroid synthesis)

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10
Q

Spironolactone (androgens)

A

Inhibits steroid binding, 17-alpha hydroxylase, and 17,20-desmolase

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11
Q

Minoxidil

Use?

A

Direct arteriolar vasodilator

Androgenic alopecia

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12
Q

1st generation antihistamines - inhibits what?

A

H1 (sedation), muscarinic, alpha-adrenergic

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13
Q

Guaifenesin

A

Expectorant - thins respiratory secretions

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14
Q

N-acetylcysteine (lungs)

A

Mucolytic - liquefies mucus by disrupting disulfide bonds

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15
Q

Dextromethorphan

Side effects?

A

Antitussive (antagonist at NMDA)

Serotonin syndrome, opioid effects

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16
Q

Pseudoephedrine vs. Phenylephrine - neuro

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A

Pseudoephedrine - CNS agitation

17
Q

Bosentan

SE?

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A

Antagonizes endothelin receptors

Hepatotoxic

18
Q

Epoprostenol, Iloprost - SEs (2)

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A

Flushing, jaw pain

19
Q

LABAs - SEs (2)

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A

Tremor, arrhythmia

20
Q

Fluticasone

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A

Inactivate NF-kB (inhaled corticosteroid)

21
Q

Budesonide

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A

Inhaled corticosteroid

22
Q

Ipratropium

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A

Muscarinic antagonist (competitive)

23
Q

-lukast

Best for what?

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A

CysLT1 receptor blockers

Aspirin-induced asthma

24
Q

Zileuton

SE?

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A

5-lipoxygenase inhibitor

Hepatotoxic

25
Theophylline - SEs MOA Blocks what?
Cardiotoxic (HTN, tachy), Neurotoxic (seizure) PDE inhibitor Blocks adenosine actions
26
Bulimia nervosa
SSRIs
27
GAD
SSRIs, SNRIs
28
OCD
SSRIs, Venlafaxine, Clomipramine
29
Panic disorder
SSRIs
30
PTSD
SSRIs
31
Tourette's
Fluphenazine, Pimozide | Tetrabenazine
32
Amphetamines - other uses besides ADHD (2)
Narcolepsy, Appetite control
33
Trifluoperazine
Typical antipsychotic (high potency)
34
Thioridazine
Typical antipsychotic (low potency)
35
Lithium - side effects
LMNOP - movement (tremor), NDI, hypOthyroid, Pregnancy problems (Ebstein)
36
NMS - symptoms Treatment?
FEVER - fever, encephalopathy, vitals unstable, enzymes increased, rigidity Dantrolene, D2 agonists (Bromocriptine)
37
Serotonin syndrome - symptoms Treatment?
AAA - activity (clonus, hyperreflexia), autonomic (hyperthermia, sweating, diarrhea), agitation Cyproheptadine (5-HT2 antagonist)
38
Risperidone - SE
Hyperprolactinemia (like typicals)

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