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Flashcards in Drugs for HBV and HCV Deck (8)
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1

What drugs are used in the tx of chronic HBV and which is preferred?

Lamviduine, emtricitabine (HIV/HBV), tenofovir, entecavir, adefovir
Tenofovir or entacavir preferred

2

Antiviral drug resistance tends to be ____ specific.

structure/sugar residue specific. Arise from mutations in HBV polymerase

3

What HBV agents have L-nucleosides?

Lamivudine

4

What HBV agents have acyclic phosphonates?

adefovir, tenofovir

5

What HBV agents have d-cyclopentane?

entecavir

6

If HBV becomes resistant to lamivudine, what will have some degree of reduced sensitivity?

entacavir

7

If HBV becomes resistant to adefovir, what will have some degree of reduced sensitivity?

tenofovir, lamivudine,

8

If HBV becomes resistant to entacavir, what will have some degree of reduced sensitivity?

lamivudine