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Dynamics 3 - Exam 3 > Drugs - Lurasidone > Flashcards

Drugs - Lurasidone Flashcards

1
Q

What is Lurasidone (Latuda)?

A

Second generation antipsychotic for treatment of schizophrenia and Bipolar I depression. D2 and 5HT2A receptor antagonist. Orally administered

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2
Q

Is there weight gain with Lurasidone?

A

no

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3
Q

What are the drug interactions of Lurasidone?

A

CYP3A4 (ketoconazole) inhibitors increase concentration

CYP3A4 (rifampin) inducers decrease concentration

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4
Q

What is the maximum recommended dose for Lurasidone?

A

80 mg. 40mg for hepatic impairment. Take with food

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5
Q

Where is Lurasidone an agonist and where is it an antagonist?

A 
Partial agonist at 5HT1A
Antagonist at:
- alpha-1
- alpha-2A and 2C
- D1, D2
- 5HT2A and 5HT7
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Dynamics 3 - Exam 3 (29 decks)

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